Stefano Pluchino Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair University of Cambridge, UK Biography Publications Institution JoVE Articles Stefano Pluchino has not added a biography. If you are Stefano Pluchino and would like to personalize this page please email our Author Liaison for assistance. Publications Wnt/β-catenin Signaling is Required to Rescue Midbrain Dopaminergic Progenitors and Promote Neurorepair in Ageing Mouse Model of Parkinson's Disease Stem Cells (Dayton, Ohio). Mar, 2014 | Pubmed ID: 24648001 Peripheral Nerve Morphogenesis Induced by Scaffold Micropatterning Biomaterials. Apr, 2014 | Pubmed ID: 24559639 Targeting Wnt Signaling at the Neuroimmune Interface for Dopaminergic Neuroprotection/repair in Parkinson's Disease Journal of Molecular Cell Biology. Feb, 2014 | Pubmed ID: 24431301 ISEV Position Paper: Extracellular Vesicle RNA Analysis and Bioinformatics Journal of Extracellular Vesicles. 2013 | Pubmed ID: 24376909 Rewiring the Ischaemic Brain with Human-induced Pluripotent Stem Cell-derived Cortical Neurons Brain : a Journal of Neurology. Dec, 2013 | Pubmed ID: 24335051 The Stem Cell Secretome and Its Role in Brain Repair Biochimie. Dec, 2013 | Pubmed ID: 23827856 How Stem Cells Speak with Host Immune Cells in Inflammatory Brain Diseases Glia. Sep, 2013 | Pubmed ID: 23633288 Neuro-immune Interactions of Neural Stem Cell Transplants: From Animal Disease Models to Human Trials Experimental Neurology. Mar, 2013 | Pubmed ID: 23507035 Uncovering Novel Actors in Astrocyte-neuron Crosstalk in Parkinson's Disease: the Wnt/β-catenin Signaling Cascade As the Common Final Pathway for Neuroprotection and Self-repair The European Journal of Neuroscience. May, 2013 | Pubmed ID: 23461676 Aging-induced Nrf2-ARE Pathway Disruption in the Subventricular Zone Drives Neurogenic Impairment in Parkinsonian Mice Via PI3K-Wnt/β-catenin Dysregulation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2013 | Pubmed ID: 23345222 Wnt Your Brain Be Inflamed? Yes, It Wnt! Trends in Molecular Medicine. Mar, 2013 | Pubmed ID: 23312954 Vesiclepedia: a Compendium for Extracellular Vesicles with Continuous Community Annotation PLoS Biology. 2012 | Pubmed ID: 23271954 Extracellular Membrane Vesicles and Immune Regulation in the Brain Frontiers in Physiology. 2012 | Pubmed ID: 22557978 Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk Between Inflammatory and Wnt/β-catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2012 | Pubmed ID: 22323720 New Perspectives of Tissue Remodelling with Neural Stem and Progenitor Cell-based Therapies Cell and Tissue Research. Jul, 2012 | Pubmed ID: 22322425 Transplanted Neural Stem/precursor Cells Instruct Phagocytes and Reduce Secondary Tissue Damage in the Injured Spinal Cord Brain : a Journal of Neurology. Feb, 2012 | Pubmed ID: 22271661 Intracerebroventricularly Delivered VEGF Promotes Contralesional Corticorubral Plasticity After Focal Cerebral Ischemia Via Mechanisms Involving Anti-inflammatory Actions Neurobiology of Disease. Mar, 2012 | Pubmed ID: 22198574 Brain Regeneration in Physiology and Pathology: the Immune Signature Driving Therapeutic Plasticity of Neural Stem Cells Physiological Reviews. Oct, 2011 | Pubmed ID: 22013212 Cyclooxygenase (COX)-1 Takes Control of Adult Hippocampal Neurogenesis Cell Cycle (Georgetown, Tex.). Oct, 2011 | Pubmed ID: 21957491 A Wnt1 Regulated Frizzled-1/β-Catenin Signaling Pathway As a Candidate Regulatory Circuit Controlling Mesencephalic Dopaminergic Neuron-astrocyte Crosstalk: Therapeutical Relevance for Neuron Survival and Neuroprotection Molecular Neurodegeneration. 2011 | Pubmed ID: 21752258 Human ESC-derived Neural Crest Model Reveals a Key Role for SOX2 in Sensory Neurogenesis Cell Stem Cell. May, 2011 | Pubmed ID: 21549328 Post-acute Delivery of Erythropoietin Induces Stroke Recovery by Promoting Perilesional Tissue Remodelling and Contralesional Pyramidal Tract Plasticity Brain : a Journal of Neurology. Jan, 2011 | Pubmed ID: 21186263 Co-graft of Allogeneic Immune Regulatory Neural Stem Cells (NPC) and Pancreatic Islets Mediates Tolerance, While Inducing NPC-derived Tumors in Mice PloS One. 2010 | Pubmed ID: 20436918 Glioma-astrocyte Interaction Modifies the Astrocyte Phenotype in a Co-culture Experimental Model Oncology Reports. Dec, 2009 | Pubmed ID: 19885586 Human Neural Stem Cells Ameliorate Autoimmune Encephalomyelitis in Non-human Primates Annals of Neurology. Sep, 2009 | Pubmed ID: 19798728 Infiltrating Blood-derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice PLoS Medicine. Jul, 2009 | Pubmed ID: 19636355 Delayed Post-ischaemic Neuroprotection Following Systemic Neural Stem Cell Transplantation Involves Multiple Mechanisms Brain : a Journal of Neurology. Aug, 2009 | Pubmed ID: 19617198 Immune Regulatory Neural Stem/precursor Cells Protect from Central Nervous System Autoimmunity by Restraining Dendritic Cell Function PloS One. 2009 | Pubmed ID: 19543526 Regeneration and Repair in Multiple Sclerosis: the Role of Cell Transplantation Neuroscience Letters. Jun, 2009 | Pubmed ID: 19429143 Persistent Inflammation Alters the Function of the Endogenous Brain Stem Cell Compartment Brain : a Journal of Neurology. Oct, 2008 | Pubmed ID: 18757884 The MPTP Mouse Model: Cues on DA Release and Neural Stem Cell Restorative Role Parkinsonism & Related Disorders. 2008 | Pubmed ID: 18579428 Neural Stem Cell-mediated Immunomodulation: Repairing the Haemorrhagic Brain Brain : a Journal of Neurology. Mar, 2008 | Pubmed ID: 18292080 The Therapeutic Plasticity of Neural Stem/precursor Cells in Multiple Sclerosis Journal of the Neurological Sciences. Feb, 2008 | Pubmed ID: 17706971 Neural Stem/precursor Cells for the Treatment of Ischemic Stroke Journal of the Neurological Sciences. Feb, 2008 | Pubmed ID: 17610905 Neural Stem Cells: Guardians of the Brain Nature Cell Biology. Sep, 2007 | Pubmed ID: 17762897 Magnetic-resonance-based Tracking and Quantification of Intravenously Injected Neural Stem Cell Accumulation in the Brains of Mice with Experimental Multiple Sclerosis Stem Cells (Dayton, Ohio). Oct, 2007 | Pubmed ID: 17600110 Synergy Between Immune Cells and Adult Neural Stem/progenitor Cells Promotes Functional Recovery from Spinal Cord Injury Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16938843 The Therapeutic Potential of Neural Stem Cells Nature Reviews. Neuroscience. May, 2006 | Pubmed ID: 16760919 Motor Evoked Potentials in a Mouse Model of Chronic Multiple Sclerosis Muscle & Nerve. Feb, 2006 | Pubmed ID: 16307439 Microglia Activated by IL-4 or IFN-gamma Differentially Induce Neurogenesis and Oligodendrogenesis from Adult Stem/progenitor Cells Molecular and Cellular Neurosciences. Jan, 2006 | Pubmed ID: 16297637 Neurosphere-derived Multipotent Precursors Promote Neuroprotection by an Immunomodulatory Mechanism Nature. Jul, 2005 | Pubmed ID: 16015332 The Therapeutic Use of Stem Cells for Myelin Repair in Autoimmune Demyelinating Disorders Journal of the Neurological Sciences. Jun, 2005 | Pubmed ID: 15896808 Neural Stem Cells and Their Use As Therapeutic Tool in Neurological Disorders Brain Research. Brain Research Reviews. Apr, 2005 | Pubmed ID: 15850660 Gene Therapy for Autoimmune Diseases Current Opinion in Molecular Therapeutics. Oct, 2004 | Pubmed ID: 15537054 Cell-based Remyelinating Therapies in Multiple Sclerosis: Evidence from Experimental Studies Current Opinion in Neurology. Jun, 2004 | Pubmed ID: 15167057 Gene Therapy-mediated Modulation of Immune Processes in the Central Nervous System Current Pharmaceutical Design. 2003 | Pubmed ID: 12871186 The Therapeutic Use of Gene Therapy in Inflammatory Demyelinating Diseases of the Central Nervous System Current Opinion in Neurology. Jun, 2003 | Pubmed ID: 12858077 Injection of Adult Neurospheres Induces Recovery in a Chronic Model of Multiple Sclerosis Nature. Apr, 2003 | Pubmed ID: 12700753 Vaccination with Amyloid-beta Peptide Induces Autoimmune Encephalomyelitis in C57/BL6 Mice Brain : a Journal of Neurology. Feb, 2003 | Pubmed ID: 12538398 Cytokine Gene Delivery into the Central Nervous System Using Intrathecally Injected Nonreplicative Viral Vectors Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12512306 Systemisk Injeksjon av Neural Stem / stamceller i Mus med kronisk EAE Matteo Donegà1, Elena Giusto1, Chiara Cossetti1, Julia Schaeffer1, Stefano Pluchino1,2 1Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, UK, 2NIHR Biomedical Research Center, University of Cambridge, UK JoVE 51154 Immunology and Infection
Systemisk Injeksjon av Neural Stem / stamceller i Mus med kronisk EAE Matteo Donegà1, Elena Giusto1, Chiara Cossetti1, Julia Schaeffer1, Stefano Pluchino1,2 1Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, UK, 2NIHR Biomedical Research Center, University of Cambridge, UK JoVE 51154 Immunology and Infection