Stephen B. McMahon Neurorestoration, Wolfson Centre for Age-Related Diseases King's College London Biography Publications Institution JoVE Articles Stephen B. McMahon has not added a biography. If you are Stephen B. McMahon and would like to personalize this page please email our Author Liaison for assistance. Publications Defining the Nociceptor Transcriptome Frontiers in Molecular Neuroscience. 2014 | Pubmed ID: 25426020 Null Mutation in SCN9A in Which Noxious Stimuli Can Be Detected in the Absence of Pain Neurology. Oct, 2014 | Pubmed ID: 25253744 Genome-wide Transcriptional Profiling of Skin and Dorsal Root Ganglia After Ultraviolet-B-induced Inflammation PloS One. 2014 | Pubmed ID: 24732968 Molecular Mechanisms Underlying the Enhanced Analgesic Effect of Oxycodone Compared to Morphine in Chemotherapy-induced Neuropathic Pain PloS One. 2014 | Pubmed ID: 24618941 Botulinum Toxin-A Treatment Reduces Human Mechanical Pain Sensitivity and Mechanotransduction Annals of Neurology. Apr, 2014 | Pubmed ID: 24550077 Pain Vulnerability: a Neurobiological Perspective Nature Neuroscience. Feb, 2014 | Pubmed ID: 24473267 A Comparison of RNA-seq and Exon Arrays for Whole Genome Transcription Profiling of the L5 Spinal Nerve Transection Model of Neuropathic Pain in the Rat Molecular Pain. 2014 | Pubmed ID: 24472155 Opening Paths to Novel Analgesics: the Role of Potassium Channels in Chronic Pain Trends in Neurosciences. Mar, 2014 | Pubmed ID: 24461875 Kv2 Dysfunction After Peripheral Axotomy Enhances Sensory Neuron Responsiveness to Sustained Input Experimental Neurology. Jan, 2014 | Pubmed ID: 24252178 Synthesis of Lipid Mediators During UVB-induced Inflammatory Hyperalgesia in Rats and Mice PloS One. 2013 | Pubmed ID: 24349046 Probing Functional Properties of Nociceptive Axons Using a Microfluidic Culture System PloS One. 2013 | Pubmed ID: 24278311 Chemokine Expression in Peripheral Tissues from the Monosodium Iodoacetate Model of Chronic Joint Pain Molecular Pain. 2013 | Pubmed ID: 24206615 A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord Injury in Rat Science Translational Medicine. Nov, 2013 | Pubmed ID: 24197736 Chemokines As Peripheral Pain Mediators Neuroscience Letters. Dec, 2013 | Pubmed ID: 24120432 PainNetworks: a Web-based Resource for the Visualisation of Pain-related Genes in the Context of Their Network Associations Pain. Dec, 2013 | Pubmed ID: 24036287 Chronic Cough and Pain: Janus Faces in Sensory Neurobiology? Pulmonary Pharmacology & Therapeutics. Oct, 2013 | Pubmed ID: 23831712 Axonal Neuregulin 1 is a Rate Limiting but Not Essential Factor for Nerve Remyelination Brain : a Journal of Neurology. Jul, 2013 | Pubmed ID: 23801741 HDAC Inhibitors Attenuate the Development of Hypersensitivity in Models of Neuropathic Pain Pain. Sep, 2013 | Pubmed ID: 23693161 Characterisation and Mechanisms of Bradykinin-evoked Pain in Man Using Iontophoresis Pain. Jun, 2013 | Pubmed ID: 23422725 Genes and Epigenetic Processes As Prospective Pain Targets Genome Medicine. 2013 | Pubmed ID: 23409739 Genes Contributing to Pain Sensitivity in the Normal Population: an Exome Sequencing Study PLoS Genetics. 2012 | Pubmed ID: 23284290 Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain Following Nerve Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23197740 Chondroitinase ABC Promotes Plasticity of Spinal Reflexes Following Peripheral Nerve Injury Experimental Neurology. Nov, 2012 | Pubmed ID: 22917776 Understanding Chronic Inflammatory and Neuropathic Pain Annals of the New York Academy of Sciences. May, 2012 | Pubmed ID: 22564068 Chronic Pain: Emerging Evidence for the Involvement of Epigenetics Neuron. Feb, 2012 | Pubmed ID: 22325197 A Regenerative Microchannel Neural Interface for Recording from and Stimulating Peripheral Axons in Vivo Journal of Neural Engineering. Feb, 2012 | Pubmed ID: 22258138 Conduction Failure Following Spinal Cord Injury: Functional and Anatomical Changes from Acute to Chronic Stages The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2011 | Pubmed ID: 22171053 Specific Involvement of Atypical PKCζ/PKMζ in Spinal Persistent Nociceptive Processing Following Peripheral Inflammation in Rat Molecular Pain. 2011 | Pubmed ID: 22054645 CXCL5 Mediates UVB Irradiation-induced Pain Science Translational Medicine. Jul, 2011 | Pubmed ID: 21734176 New Molecules for the Treatment of Pain Current Opinion in Supportive and Palliative Care. Jun, 2011 | Pubmed ID: 21455071 Perturbing PSD-95 Interactions with NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic Pain Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2011 | Pubmed ID: 21427709 Delayed Treatment with Chondroitinase ABC Reverses Chronic Atrophy of Rubrospinal Neurons Following Spinal Cord Injury Experimental Neurology. Mar, 2011 | Pubmed ID: 21215745 Systemic Blockade of P2X3 and P2X2/3 Receptors Attenuates Bone Cancer Pain Behaviour in Rats Brain : a Journal of Neurology. Sep, 2010 | Pubmed ID: 20802203 Cortical Overexpression of Neuronal Calcium Sensor-1 Induces Functional Plasticity in Spinal Cord Following Unilateral Pyramidal Tract Injury in Rat PLoS Biology. 2010 | Pubmed ID: 20585375 Ultraviolet-B-induced Mechanical Hyperalgesia: A Role for Peripheral Sensitisation Pain. Jul, 2010 | Pubmed ID: 20478657 Endogenous Purinergic Control of Bladder Activity Via Presynaptic P2X3 and P2X2/3 Receptors in the Spinal Cord The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010 | Pubmed ID: 20335487 P2X7-dependent Release of Interleukin-1beta and Nociception in the Spinal Cord Following Lipopolysaccharide The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20071520 Identification of Perineal Sensory Neurons Activated by Innocuous Heat The Journal of Comparative Neurology. Jan, 2010 | Pubmed ID: 19937707 Neural Progenitors Promote Axon Growth in Vitro and Ex Vivo but Not Following Injury Journal of Stem Cells. 2009 | Pubmed ID: 20498687 Current Challenges in Glia-pain Biology Neuron. Oct, 2009 | Pubmed ID: 19840548 Future Treatment Strategies for Neuropathic Pain Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19655119 Sensory Axon-derived Neuregulin-1 is Required for Axoglial Signaling and Normal Sensory Function but Not for Long-term Axon Maintenance The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2009 | Pubmed ID: 19535578 Microchannel Electrodes for Recording and Stimulation: in Vitro Evaluation IEEE Transactions on Bio-medical Engineering. May, 2009 | Pubmed ID: 19203882 Expression of the Regeneration-associated Protein SPRR1A in Primary Sensory Neurons and Spinal Cord of the Adult Mouse Following Peripheral and Central Injury The Journal of Comparative Neurology. Mar, 2009 | Pubmed ID: 19107756 Effects of Etanercept and Minocycline in a Rat Model of Spinal Cord Injury European Journal of Pain (London, England). Aug, 2009 | Pubmed ID: 18849175 Mice Lacking Acid-sensing Ion Channels (ASIC) 1 or 2, but Not ASIC3, Show Increased Pain Behaviour in the Formalin Test European Journal of Pain (London, England). Jul, 2009 | Pubmed ID: 18801682 Ultraviolet-B Induced Inflammation of Human Skin: Characterisation and Comparison with Traditional Models of Hyperalgesia European Journal of Pain (London, England). May, 2009 | Pubmed ID: 18691920 Comparison of Dorsal Root Ganglion Gene Expression in Rat Models of Traumatic and HIV-associated Neuropathic Pain European Journal of Pain (London, England). Apr, 2009 | Pubmed ID: 18606552 CCL2 is a Key Mediator of Microglia Activation in Neuropathic Pain States European Journal of Pain (London, England). Mar, 2009 | Pubmed ID: 18554968 The Yellow Fluorescent Protein (YFP-H) Mouse Reveals Neuroprotection As a Novel Mechanism Underlying Chondroitinase ABC-mediated Repair After Spinal Cord Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19109493 Chondroitinase ABC-mediated Plasticity of Spinal Sensory Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008 | Pubmed ID: 19005065 Phosphatidylinositol 3-kinase is a Key Mediator of Central Sensitization in Painful Inflammatory Conditions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18417706 Microchannels As Axonal Amplifiers IEEE Transactions on Bio-medical Engineering. Mar, 2008 | Pubmed ID: 18334406 Modulation of Acid-sensing Ion Channel Activity by Nitric Oxide The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2007 | Pubmed ID: 18045919 Transplanted Neural Progenitor Cells Survive and Differentiate but Achieve Limited Functional Recovery in the Lesioned Adult Rat Spinal Cord Regenerative Medicine. Nov, 2007 | Pubmed ID: 18034631 Heritability of Responses to Painful Stimuli in Women: a Classical Twin Study Brain : a Journal of Neurology. Nov, 2007 | Pubmed ID: 17932101 Characterization of Rodent Models of HIV-gp120 and Anti-retroviral-associated Neuropathic Pain Brain : a Journal of Neurology. Oct, 2007 | Pubmed ID: 17761732 Pathophysiology of Peripheral Neuropathic Pain: Immune Cells and Molecules Anesthesia and Analgesia. Sep, 2007 | Pubmed ID: 17717248 The Activation of the ERK Pathway Contributes to the Spinal C-fos Expression Observed After Noxious Bladder Stimulation Somatosensory & Motor Research. Mar-Jun, 2007 | Pubmed ID: 17558919 Pharmacological, Behavioural and Mechanistic Analysis of HIV-1 Gp120 Induced Painful Neuropathy Pain. Dec, 2007 | Pubmed ID: 17433546 Role of Spinal Microglia in Rat Models of Peripheral Nerve Injury and Inflammation European Journal of Pain (London, England). Feb, 2007 | Pubmed ID: 16545974 Artemin Has Potent Neurotrophic Actions on Injured C-fibres Journal of the Peripheral Nervous System : JPNS. Dec, 2006 | Pubmed ID: 17117942 Nerve Injury Induces Robust Allodynia and Ectopic Discharges in Nav1.3 Null Mutant Mice Molecular Pain. 2006 | Pubmed ID: 17052333 Lentiviral Vector Expressing Retinoic Acid Receptor Beta2 Promotes Recovery of Function After Corticospinal Tract Injury in the Adult Rat Spinal Cord Human Molecular Genetics. Nov, 2006 | Pubmed ID: 16984961 Rapid Co-release of Interleukin 1beta and Caspase 1 in Spinal Cord Inflammation Journal of Neurochemistry. Nov, 2006 | Pubmed ID: 16942597 Spinal Cord Repair Strategies: Why Do They Work? Nature Reviews. Neuroscience. Aug, 2006 | Pubmed ID: 16858392 Neurotrophins: Mediators and Modulators of Pain Annual Review of Neuroscience. 2006 | Pubmed ID: 16776595 Increasingly Irritable and Close to Tears: TRPA1 in Inflammatory Pain Cell. Mar, 2006 | Pubmed ID: 16564004 Spinal ERK Activation Contributes to the Regulation of Bladder Function in Spinal Cord Injured Rats Experimental Neurology. Jul, 2006 | Pubmed ID: 16513110 Reversal of Neurochemical Changes and Pain-related Behavior in a Model of Neuropathic Pain Using Modified Lentiviral Vectors Expressing GDNF Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2006 | Pubmed ID: 16504588 A Clonal Cell Line from Immortalized Olfactory Ensheathing Glia Promotes Functional Recovery in the Injured Spinal Cord Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2006 | Pubmed ID: 16427362 ATF3 Expression in L4 Dorsal Root Ganglion Neurons After L5 Spinal Nerve Transection The European Journal of Neuroscience. Jan, 2006 | Pubmed ID: 16420444 Nociceptor-derived Brain-derived Neurotrophic Factor Regulates Acute and Inflammatory but Not Neuropathic Pain Molecular and Cellular Neurosciences. Mar, 2006 | Pubmed ID: 16413788 Retinoic Acid Receptor Beta2 Promotes Functional Regeneration of Sensory Axons in the Spinal Cord Nature Neuroscience. Feb, 2006 | Pubmed ID: 16388307 Assessing Behavioural Function Following a Pyramidotomy Lesion of the Corticospinal Tract in Adult Mice Experimental Neurology. Oct, 2005 | Pubmed ID: 16051217 Role of the Immune System in Chronic Pain Nature Reviews. Neuroscience. Jul, 2005 | Pubmed ID: 15995723 Inhibition of ERK Phosphorylation Decreases Nociceptive Behaviour in Monoarthritic Rats Pain. Aug, 2005 | Pubmed ID: 15979799 TrkB Expression and Phospho-ERK Activation by Brain-derived Neurotrophic Factor in Rat Spinothalamic Tract Neurons The Journal of Comparative Neurology. Aug, 2005 | Pubmed ID: 15977164 P2X2 Knockout Mice and P2X2/P2X3 Double Knockout Mice Reveal a Role for the P2X2 Receptor Subunit in Mediating Multiple Sensory Effects of ATP The Journal of Physiology. Sep, 2005 | Pubmed ID: 15961431 Activity-dependent Phosphorylation of Akt/PKB in Adult DRG Neurons The European Journal of Neuroscience. Apr, 2005 | Pubmed ID: 15869474 Immune and Glial Cell Factors As Pain Mediators and Modulators Experimental Neurology. Apr, 2005 | Pubmed ID: 15755561 Regulation of Neuropilin 1 by Spinal Cord Injury in Adult Rats Molecular and Cellular Neurosciences. Mar, 2005 | Pubmed ID: 15737738 Increased Spinal Cord Phosphorylation of Extracellular Signal-regulated Kinases Mediates Micturition Overactivity in Rats with Chronic Bladder Inflammation The European Journal of Neuroscience. Feb, 2005 | Pubmed ID: 15733095 Conditioning Injury-induced Spinal Axon Regeneration Requires Signal Transducer and Activator of Transcription 3 Activation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2005 | Pubmed ID: 15716400 Acid-induced Pain and Its Modulation in Humans The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2004 | Pubmed ID: 15574747 Neurotrophic Influences on Neuropathic Pain Novartis Foundation Symposium. 2004 | Pubmed ID: 15469045 Brain-derived Neurotrophic Factor Induces NMDA Receptor Subunit One Phosphorylation Via ERK and PKC in the Rat Spinal Cord The European Journal of Neuroscience. Oct, 2004 | Pubmed ID: 15379998 Plasticity of Pain Signaling: Role of Neurotrophic Factors Exemplified by Acid-induced Pain Journal of Neurobiology. Oct, 2004 | Pubmed ID: 15362154 Conditioning Injury-induced Spinal Axon Regeneration Fails in Interleukin-6 Knock-out Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2004 | Pubmed ID: 15128857 NGF and GDNF Ameliorate the Increase in ATF3 Expression Which Occurs in Dorsal Root Ganglion Cells in Response to Peripheral Nerve Injury The European Journal of Neuroscience. Mar, 2004 | Pubmed ID: 15066140 Ultraviolet Radiation-induced Inflammation As a Model for Cutaneous Hyperalgesia The Journal of Investigative Dermatology. Jan, 2004 | Pubmed ID: 14962107 Glial Cell Line-derived Neurotrophic Factor Increases Calcitonin Gene-related Peptide Immunoreactivity in Sensory and Motoneurons in Vivo The European Journal of Neuroscience. Nov, 2003 | Pubmed ID: 14656320 The Signaling Components of Sensory Fiber Transmission Involved in the Activation of ERK MAP Kinase in the Mouse Dorsal Horn Molecular and Cellular Neurosciences. Oct, 2003 | Pubmed ID: 14572451 EphB Receptors and Ephrin-B Ligands Regulate Spinal Sensory Connectivity and Modulate Pain Processing Nature Neuroscience. Apr, 2003 | Pubmed ID: 12640461 BDNF: a Neuromodulator in Nociceptive Pathways? Brain Research. Brain Research Reviews. Oct, 2002 | Pubmed ID: 12589922 Noxious Stimulation Induces Trk Receptor and Downstream ERK Phosphorylation in Spinal Dorsal Horn Molecular and Cellular Neurosciences. Dec, 2002 | Pubmed ID: 12504600 Molecular Forms of NGF in Human and Rat Neuropathic Tissues: Decreased NGF Precursor-like Immunoreactivity in Human Diabetic Skin Journal of the Peripheral Nervous System : JPNS. Sep, 2002 | Pubmed ID: 12365567 Chondroitinase ABC Promotes Functional Recovery After Spinal Cord Injury Nature. Apr, 2002 | Pubmed ID: 11948352 Neurotrophin-3-mediated Regeneration and Recovery of Proprioception Following Dorsal Rhizotomy Molecular and Cellular Neurosciences. Feb, 2002 | Pubmed ID: 11860276 P2X Receptors and Their Role in Female Idiopathic Detrusor Instability The Journal of Urology. Jan, 2002 | Pubmed ID: 11743296 Ensidig Pyramidotomy af corticospinal Tract i rotter for Vurdering af neuroplasticitet-fremkaldende Terapier Claudia Kathe1, Thomas H. Hutson1, Qin Chen2, Harold D. Shine2, Stephen B. McMahon1, Lawrence D. F. Moon1 1Neurorestoration, Wolfson Centre for Age-Related Diseases, King's College London, 2Department of Neuroscience, Baylor College of Medicine JoVE 51843 Neuroscience
Ensidig Pyramidotomy af corticospinal Tract i rotter for Vurdering af neuroplasticitet-fremkaldende Terapier Claudia Kathe1, Thomas H. Hutson1, Qin Chen2, Harold D. Shine2, Stephen B. McMahon1, Lawrence D. F. Moon1 1Neurorestoration, Wolfson Centre for Age-Related Diseases, King's College London, 2Department of Neuroscience, Baylor College of Medicine JoVE 51843 Neuroscience