Steven Guard Molecular Cellular and Developmental Biology University of Colorado Boulder Biography Publications Institution JoVE Articles Steven GuardGraduate Student Steven Guard is a Ph.D candidate in the Molecular, Cellular and Developmental Biology Department at the University of Colorado Boulder. He graduated from the University of Cincinnati in 2015 with a bachelor's degree in Chemical Engineering and a bachelor's degree in neurobiology.His first research experience was in Dr. Nancy Ratner’s lab at Cincinnati Children’s Hospital studying the tumor suppressor gene Merlin. Soon after, he continued his research career as an ASPET SURF fellow in Dr. Zalfa Abdel-Malek’s lab at the University of Cincinnati studying melanoma susceptibility and senescence. As a graduate student in Dr. William Old's lab, he received training in mutliple omics technologies and explored several biological contexts in which they could be applied. Steven spent the beginning of his graduate studies investigating the interaction partners of the CMGC kinase, DYRK1A, and a novel role for this kinase in the regulation of DNA double strand break repair. Recently he has expanded his studies to uncovering novel drug mechanisms by leveraging an unbiased multiomics platform of the proteome, phosphoproteome, transcriptome, metabolome, and thermal proteome profiling. Publications Immunoprecipitation ללא תווית של זרימת עבודה בהיקפים גדולים של החברה ליצירת פרופיל רב-ממדי של Interactome גרעינית Steven E. Guard1, Christopher C. Ebmeier1, William M. Old1,2 1Department of Molecular, Cellular and Developmental Biology, University of Colorado, 2Linda Crnic Institute for Down Syndrome, University of Colorado School of Medicine JoVE 60432 Biochemistry
Immunoprecipitation ללא תווית של זרימת עבודה בהיקפים גדולים של החברה ליצירת פרופיל רב-ממדי של Interactome גרעינית Steven E. Guard1, Christopher C. Ebmeier1, William M. Old1,2 1Department of Molecular, Cellular and Developmental Biology, University of Colorado, 2Linda Crnic Institute for Down Syndrome, University of Colorado School of Medicine JoVE 60432 Biochemistry