Stuart C. Sealfon Center for Translational Systems Biology and Department of Neurology Mount Sinai School of Medicine Biography Publications Institution JoVE Articles Stuart C. Sealfon has not added a biography. If you are Stuart C. Sealfon and would like to personalize this page please email our Author Liaison for assistance. Publications Optimized Amplification and Single-cell Analysis Identify GnRH-mediated Activation of Rap1b in Primary Rat Gonadotropes Molecular and Cellular Endocrinology. Mar, 2012 | Pubmed ID: 22127306 Multi-scale Stochastic Simulation of Diffusion-coupled Agents and Its Application to Cell Culture Simulation PloS One. 2011 | Pubmed ID: 22216238 Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs Cell. Nov, 2011 | Pubmed ID: 22118459 Authors Response to Correspondence About an Improved Compensation Method Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2011 | Pubmed ID: 22065546 Functional Crosstalk and Heteromerization of Serotonin 5-HT2A and Dopamine D2 Receptors Neuropharmacology. Sep, 2011 | Pubmed ID: 21645528 Improved Compensation in Flow Cytometry by Multivariable Optimization Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2011 | Pubmed ID: 21485003 Characterization of a MAPK Scaffolding Protein Logic Gate in Gonadotropes Molecular Endocrinology (Baltimore, Md.). Jun, 2011 | Pubmed ID: 21436256 Differential Gene Expression in Patients with Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. Jul, 2011 | Pubmed ID: 21375368 Role of Cell-to-cell Variability in Activating a Positive Feedback Antiviral Response in Human Dendritic Cells PloS One. 2011 | Pubmed ID: 21347441 Metabotropic Glutamate MGlu2 Receptor is Necessary for the Pharmacological and Behavioral Effects Induced by Hallucinogenic 5-HT2A Receptor Agonists Neuroscience Letters. Apr, 2011 | Pubmed ID: 21276828 RNA and DNA Microarrays Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 20967621 Misty Mountain Clustering: Application to Fast Unsupervised Flow Cytometry Gating BMC Bioinformatics. 2010 | Pubmed ID: 20932336 Signaling Network of Dendritic Cells in Response to Pathogens: a Community-input Supported Knowledgebase BMC Systems Biology. 2010 | Pubmed ID: 20929569 Validation of Efficient High-throughput Plasmid and SiRNA Transfection of Human Monocyte-derived Dendritic Cells Without Cell Maturation Journal of Immunological Methods. Dec, 2010 | Pubmed ID: 20875421 Novel Nipah Virus Immune-antagonism Strategy Revealed by Experimental and Computational Study Journal of Virology. Nov, 2010 | Pubmed ID: 20739535 Heteromerization of G Protein-coupled Receptors: Relevance to Neurological Disorders and Neurotherapeutics CNS & Neurological Disorders Drug Targets. Nov, 2010 | Pubmed ID: 20632964 Research Resource: Gonadotropin-releasing Hormone Receptor-mediated Signaling Network in LbetaT2 Cells: a Pathway-based Web-accessible Knowledgebase Molecular Endocrinology (Baltimore, Md.). Sep, 2010 | Pubmed ID: 20592162 Plato's Cave Algorithm: Inferring Functional Signaling Networks from Early Gene Expression Shadows PLoS Computational Biology. Jun, 2010 | Pubmed ID: 20585619 Coregulation Mapping Based on Individual Phenotypic Variation in Response to Virus Infection Immunome Research. 2010 | Pubmed ID: 20298589 Antiviral Response Dictated by Choreographed Cascade of Transcription Factors Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20164420 Immune Response Modeling of Interferon Beta-pretreated Influenza Virus-infected Human Dendritic Cells Biophysical Journal. Feb, 2010 | Pubmed ID: 20159146 Multiple Testing and Its Applications to Microarrays Statistical Methods in Medical Research. Dec, 2009 | Pubmed ID: 20048384 Group II Metabotropic Glutamate Receptors and Schizophrenia Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19707855 Model of Autocrine/paracrine Signaling in Epithelial Layer: Geometrical Regulation of Intercellular Communication The Journal of Physical Chemistry. B. Aug, 2009 | Pubmed ID: 19601596 Microtranscriptome Regulation by Gonadotropin-releasing Hormone Molecular and Cellular Endocrinology. Apr, 2009 | Pubmed ID: 19356622 Agonist-trafficking and Hallucinogens Current Medicinal Chemistry. 2009 | Pubmed ID: 19275609 Psychedelics and Schizophrenia Trends in Neurosciences. Apr, 2009 | Pubmed ID: 19269047 SOME STEP-DOWN PROCEDURES CONTROLLING THE FALSE DISCOVERY RATE UNDER DEPENDENCE Statistica Sinica. 2008 | Pubmed ID: 19018297 Antiviral-activated Dendritic Cells: a Paracrine-induced Response State Journal of Immunology (Baltimore, Md. : 1950). Nov, 2008 | Pubmed ID: 18981106 Interferon-beta Pretreatment of Conventional and Plasmacytoid Human Dendritic Cells Enhances Their Activation by Influenza Virus PLoS Pathogens. Oct, 2008 | Pubmed ID: 18974865 A Comprehensive Evaluation of Human Plasmacytoid Dendritic Cells Using Small Volumes of Human Blood Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Aug, 2008 | Pubmed ID: 18729740 Receptor Pair for Schizophrenia Pediatric Research. Jul, 2008 | Pubmed ID: 18574404 Cell-to-cell Communication: Time and Length Scales of Ligand Internalization in Cultures of Suspended Cells The Journal of Chemical Physics. Jun, 2008 | Pubmed ID: 18554059 Getting Started in Biological Pathway Construction and Analysis PLoS Computational Biology. Feb, 2008 | Pubmed ID: 18463709 Identification of a Serotonin/glutamate Receptor Complex Implicated in Psychosis Nature. Mar, 2008 | Pubmed ID: 18297054 Time and Length Scales of Autocrine Signals in Three Dimensions Biophysical Journal. Sep, 2007 | Pubmed ID: 17720734 Noise Propagation and Scaling in Regulation of Gonadotrope Biosynthesis Biophysical Journal. Dec, 2007 | Pubmed ID: 17720728 Chromosome-specific and Noisy IFNB1 Transcription in Individual Virus-infected Human Primary Dendritic Cells Nucleic Acids Research. 2007 | Pubmed ID: 17675303 BioPP: a Tool for Web-publication of Biological Networks BMC Bioinformatics. 2007 | Pubmed ID: 17519033 Bone Morphogenetic Protein 2 and Activin A Synergistically Stimulate Follicle-stimulating Hormone Beta Subunit Transcription Journal of Molecular Endocrinology. Feb, 2007 | Pubmed ID: 17293449 Biphasic Effects of Postnatal Exposure to Diethylhexylphthalate on the Timing of Puberty in Male Rats Journal of Andrology. Jul-Aug, 2007 | Pubmed ID: 17287459 Hallucinogens Recruit Specific Cortical 5-HT(2A) Receptor-mediated Signaling Pathways to Affect Behavior Neuron. Feb, 2007 | Pubmed ID: 17270739 P53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17060322 Mixed Analog/digital Gonadotrope Biosynthetic Response to Gonadotropin-releasing Hormone The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16916798 Cortical 5-HT2A Receptor Signaling Modulates Anxiety-like Behaviors in Mice Science (New York, N.Y.). Jul, 2006 | Pubmed ID: 16873667 Influenza Virus Evades Innate and Adaptive Immunity Via the NS1 Protein Journal of Virology. Jul, 2006 | Pubmed ID: 16775317 The Human Herpesvirus 8 Chemokine Receptor VGPCR Triggers Autonomous Proliferation of Endothelial Cells The Journal of Clinical Investigation. May, 2006 | Pubmed ID: 16604194 Chronic Exposure to TNF-alpha Increases Airway Mucus Gene Expression in Vivo The Journal of Allergy and Clinical Immunology. Dec, 2005 | Pubmed ID: 16337454 Method for Multiplex Cellular Detection of MRNAs Using Quantum Dot Fluorescent in Situ Hybridization Nucleic Acids Research. 2005 | Pubmed ID: 16224100 Transcript Profiling of Immediate Early Genes Reveals a Unique Role for Activating Transcription Factor 3 in Mediating Activation of the Glycoprotein Hormone Alpha-subunit Promoter by Gonadotropin-releasing Hormone Molecular Endocrinology (Baltimore, Md.). Oct, 2005 | Pubmed ID: 15961508 Local Protein Synthesis Mediates a Rapid Increase in Dendritic Elongation Factor 1A After Induction of Late Long-term Potentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15958750 Teaching Resources. G-protein-coupled Receptors Science's STKE : Signal Transduction Knowledge Environment. Apr, 2005 | Pubmed ID: 15827322 Acute Induction of Gene Expression in Brain and Liver by Insulin-induced Hypoglycemia Diabetes. Apr, 2005 | Pubmed ID: 15793232 CXC Chemokine Receptors on Human Oligodendrocytes: Implications for Multiple Sclerosis Brain : a Journal of Neurology. May, 2005 | Pubmed ID: 15774504 Epsilon-sarcoglycan Immunoreactivity and MRNA Expression in Mouse Brain The Journal of Comparative Neurology. Jan, 2005 | Pubmed ID: 15612018 Mutational Analysis of the Serotonin Receptor 5HT2c in Severe Early-onset Human Obesity Canadian Journal of Physiology and Pharmacology. Jun, 2004 | Pubmed ID: 15381968 Genomics View of Gonadotrope Signaling Circuits Trends in Endocrinology and Metabolism: TEM. Sep, 2004 | Pubmed ID: 15350605 Mining Microarrays for Metabolic Meaning: Nutritional Regulation of Hypothalamic Gene Expression Neurochemical Research. Jun, 2004 | Pubmed ID: 15176466 Early Single Cell Bifurcation of Pro- and Antiapoptotic States During Oxidative Stress The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15078887 Focused Microarray Analysis Methods (San Diego, Calif.). Dec, 2003 | Pubmed ID: 14597315 Structure of the GnRH Receptor-stimulated Signaling Network: Insights from Genomics Frontiers in Neuroendocrinology. Jul, 2003 | Pubmed ID: 14596811 Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14523084 Agonist-specific Transactivation of Phosphoinositide 3-kinase Signaling Pathway Mediated by the Dopamine D2 Receptor The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12970364 Activation of Phosphoinositide 3-kinase by D2 Receptor Prevents Apoptosis in Dopaminergic Cell Lines The Biochemical Journal. Jul, 2003 | Pubmed ID: 12683952 Molecular Basis of Partial Agonism: Orientation of Indoleamine Ligands in the Binding Pocket of the Human Serotonin 5-HT2A Receptor Determines Relative Efficacy Molecular Pharmacology. Jan, 2003 | Pubmed ID: 12488534 Validated Genomic Approach to Study Differentially Expressed Genes in Complex Tissues Neurochemical Research. Oct, 2002 | Pubmed ID: 12462402 Conserved Helix 7 Tyrosine Acts As a Multistate Conformational Switch in the 5HT2C Receptor. Identification of a Novel "locked-on" Phenotype and Double Revertant Mutations The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12145300 Coupling of GnRH Concentration and the GnRH Receptor-activated Gene Program Molecular Endocrinology (Baltimore, Md.). Jun, 2002 | Pubmed ID: 12040003 Accuracy and Calibration of Commercial Oligonucleotide and Custom CDNA Microarrays Nucleic Acids Research. May, 2002 | Pubmed ID: 12000853 Monitoring G-protein-coupled Receptor Signaling with DNA Microarrays and Real-time Polymerase Chain Reaction Methods in Enzymology. 2002 | Pubmed ID: 11665639 Strategies for Mapping the Binding Site of the Serotonin 5-HT2A Receptor Methods in Enzymology. 2002 | Pubmed ID: 11665561 Optimerade protokoll för effektiv Transfektion av dendritiska celler utan cellmognaden Robert Bowles*1, Sonali Patil*1, Hanna Pincas1, Stuart C. Sealfon1 1Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine JoVE 2766 Immunology and Infection
Optimerade protokoll för effektiv Transfektion av dendritiska celler utan cellmognaden Robert Bowles*1, Sonali Patil*1, Hanna Pincas1, Stuart C. Sealfon1 1Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine JoVE 2766 Immunology and Infection