Sylvie Lesage Département de Microbiologie, Infectiologie, Immunologie Centre de recherche de l'Hôpital Maisonneuve-Rosemont Biography Publications Institution JoVE Articles Sylvie Lesage has not added a biography. If you are Sylvie Lesage and would like to personalize this page please email our Author Liaison for assistance. Publications TCR Transgenic Mice Reveal the Impact of Type 1 Diabetes Loci on Early and Late Disease Checkpoints Immunology and Cell Biology. Aug, 2016 | Pubmed ID: 27046082 Genetic Predisposition for Beta Cell Fragility Underlies Type 1 and Type 2 Diabetes Nature Genetics. May, 2016 | Pubmed ID: 26998692 IL23R (Interleukin 23 Receptor) Variants Protective Against Inflammatory Bowel Diseases (IBD) Display Loss of Function Due to Impaired Protein Stability and Intracellular Trafficking The Journal of Biological Chemistry. Apr, 2016 | Pubmed ID: 26887945 NK Cell Proportion and Number Are Influenced by Genetic Loci on Chromosomes 8, 9, and 17 Journal of Immunology (Baltimore, Md. : 1950). Mar, 2016 | Pubmed ID: 26851217 Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity The Journal of Biological Chemistry. Feb, 2016 | Pubmed ID: 26742847 Autoimmunity and Antibody Affinity Maturation Are Modulated by Genetic Variants on Mouse Chromosome 12 Journal of Autoimmunity. Apr, 2015 | Pubmed ID: 25623266 Functional Characterization of CaVα2δ Mutations Associated with Sudden Cardiac Death The Journal of Biological Chemistry. Jan, 2015 | Pubmed ID: 25527503 Specific Targeting of the IL-23 Receptor, Using a Novel Small Peptide Noncompetitive Antagonist, Decreases the Inflammatory Response American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Nov, 2014 | Pubmed ID: 25354400 The Mouse Idd2 Locus is Linked to the Proportion of Immunoregulatory Double-negative T Cells, a Trait Associated with Autoimmune Diabetes Resistance Journal of Immunology (Baltimore, Md. : 1950). Oct, 2014 | Pubmed ID: 25165153 The Dichotomous Pattern of IL-12r and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation PloS One. 2014 | Pubmed ID: 24586521 A ZAP-70 Kinase Domain Variant Prevents Thymocyte-positive Selection Despite Signalling CD69 Induction Immunology. Apr, 2014 | Pubmed ID: 24266404 Revisiting the Prominent Anti-Tumoral Potential of Pre-mNK Cells Frontiers in Immunology. 2013 | Pubmed ID: 24376447 Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice Journal of Diabetes Research. 2013 | Pubmed ID: 23691516 The Idd13 Congenic Interval Defines the Number of Merocytic Dendritic Cells, A novel Trait Associated with Autoimmune Diabetes Susceptibility Journal of Autoimmunity. Jun, 2013 | Pubmed ID: 23623717 Immunoregulatory CD4(-)CD8(-) T Cells As a Potential Therapeutic Tool for Transplantation, Autoimmunity, and Cancer Frontiers in Immunology. 2013 | Pubmed ID: 23355840 Unusual Selection and Peripheral Homeostasis for Immunoregulatory CD4(-) CD8(-) T Cells Immunology. May, 2013 | Pubmed ID: 23293940 A Comprehensive Review of the Phenotype and Function of Antigen-specific Immunoregulatory Double Negative T Cells Journal of Autoimmunity. Feb, 2013 | Pubmed ID: 22910322 The Size of the Plasmacytoid Dendritic Cell Compartment is a Multigenic Trait Dominated by a Locus on Mouse Chromosome 7 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2012 | Pubmed ID: 22547694 Redefining Interferon-producing Killer Dendritic Cells As a Novel Intermediate in NK-cell Differentiation Blood. May, 2012 | Pubmed ID: 22353997 Molecular and Genetic Parameters Defining T-cell Clonal Selection Immunology and Cell Biology. Jan, 2011 | Pubmed ID: 20956988 Interleukin-10 Limits the Expansion of Immunoregulatory CD4-CD8- T Cells in Autoimmune-prone Non-obese Diabetic Mice Immunology and Cell Biology. Nov-Dec, 2010 | Pubmed ID: 20603635 Implication of the CD47 Pathway in Autoimmune Diabetes Journal of Autoimmunity. Aug, 2010 | Pubmed ID: 20138735 Cutting Edge: Genetic Characterization of IFN-producing Killer Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19380763 Absence of CD47 in Vivo Influences Thymic Dendritic Cell Subset Proportions but Not Negative Selection of Thymocytes International Immunology. Feb, 2009 | Pubmed ID: 19147837 Cutting Edge: CD47 Controls the in Vivo Proliferation and Homeostasis of Peripheral CD4+ CD25+ Foxp3+ Regulatory T Cells That Express CD103 Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18832672 Expression of the Self-marker CD47 on Dendritic Cells Governs Their Trafficking to Secondary Lymphoid Organs The EMBO Journal. Nov, 2006 | Pubmed ID: 17093498 Genetic Lesions in T-cell Tolerance and Thresholds for Autoimmunity Immunological Reviews. Apr, 2005 | Pubmed ID: 15790352 Generalized Resistance to Thymic Deletion in the NOD Mouse; a Polygenic Trait Characterized by Defective Induction of Bim Immunity. Dec, 2004 | Pubmed ID: 15589170 Gene Dosage--limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity The Journal of Experimental Medicine. Oct, 2004 | Pubmed ID: 15492124 A Cell Death Pathway Induced by Antibody-mediated Cross-linking of CD45 on Lymphocytes Critical Reviews in Immunology. 2003 | Pubmed ID: 15030310 Identifying the MAGUK Protein Carma-1 As a Central Regulator of Humoral Immune Responses and Atopy by Genome-wide Mouse Mutagenesis Immunity. Jun, 2003 | Pubmed ID: 12818157 T Cell Tolerance to a Neo-self Antigen Expressed by Thymic Epithelial Cells: the Soluble Form is More Effective Than the Membrane-bound Form Journal of Immunology (Baltimore, Md. : 1950). Apr, 2003 | Pubmed ID: 12682222 Aire Regulates Negative Selection of Organ-specific T Cells Nature Immunology. Apr, 2003 | Pubmed ID: 12612579 Failure to Censor Forbidden Clones of CD4 T Cells in Autoimmune Diabetes The Journal of Experimental Medicine. Nov, 2002 | Pubmed ID: 12417628 Spinal Cord Compression of Dual Etiology, Multiple Myeloma and Spinal Tuberculosis Leukemia & Lymphoma. Feb, 2002 | Pubmed ID: 11999581 Akım Sitometri Kullanımı rekombinant İyon Kanallarının göreli Hücre Yüzey ve toplam İfade tayini Benoîte Bourdin1, Emilie Segura1, Marie-Philippe Tétreault1, Sylvie Lesage2, Lucie Parent1 1Département de Physiologie Moléculaire et Intégrative, Montreal Heart Institute Research Centre, 2Département de Microbiologie, Infectiologie, Immunologie, Centre de recherche de l'Hôpital Maisonneuve-Rosemont JoVE 54732 Biology
Akım Sitometri Kullanımı rekombinant İyon Kanallarının göreli Hücre Yüzey ve toplam İfade tayini Benoîte Bourdin1, Emilie Segura1, Marie-Philippe Tétreault1, Sylvie Lesage2, Lucie Parent1 1Département de Physiologie Moléculaire et Intégrative, Montreal Heart Institute Research Centre, 2Département de Microbiologie, Infectiologie, Immunologie, Centre de recherche de l'Hôpital Maisonneuve-Rosemont JoVE 54732 Biology