Thomas Rich Center for Lung Biology, College of Medicine University of South Alabama Biography Publications Institution JoVE Articles Thomas Rich has not added a biography. If you are Thomas Rich and would like to personalize this page please email our Author Liaison for assistance. Publications Phosphodiesterase 4 Mediates Interleukin-8-induced Heterologous Desensitization of the β -adrenergic Receptor FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 10, 2021 | Pubmed ID: 34555226 Excitation-scanning Hyperspectral Video Endoscopy: Enhancing the Light at the End of the Tunnel Biomedical Optics Express. Jan, 2021 | Pubmed ID: 33520384 Excitation-scan Mirror Array System Advancements to Hyperspectral Imaging Applications Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2020 | Pubmed ID: 34121795 Spectral Illumination System Utilizing Spherical Reflection Optics Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2020 | Pubmed ID: 34045787 Comparison of Spectral FRET Microscopy Approaches for Single-cell Analysis Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2020 | Pubmed ID: 34035557 Optical Simulations for Determining Efficacy of New Light Source Designs for Excitation-scanning High-speed Hyperspectral Imaging Systems Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2020 | Pubmed ID: 34035556 Milestones in the Development and Implementation of FRET-based Sensors of Intracellular Signals: A Biological Perspective of the History of FRET Cellular Signalling. Nov, 2020 | Pubmed ID: 32898611 Development of an Endothelial Cell-restricted Transgenic Reporter Rat: a Resource for Physiological Studies of Vascular Biology American Journal of Physiology. Heart and Circulatory Physiology. 08, 2020 | Pubmed ID: 32589443 CAMP Signaling Primes Lung Endothelial Cells to Activate Caspase-1 During Infection American Journal of Physiology. Lung Cellular and Molecular Physiology. 05, 2020 | Pubmed ID: 32186399 Label-free Spectroscopic Tissue Characterization Using Fluorescence Excitation-scanning Spectral Imaging Journal of Biophotonics. 02, 2020 | Pubmed ID: 31566889 Sensitivity Analysis of a Multibranched Light Guide for Real Time Hyperspectral Imaging Systems Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34092891 Hyperspectral Imaging Fluorescence Excitation Scanning Spectral Characteristics of Remodeled Mouse Arteries Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34045786 Hyperspectral Imaging Fluorescence Excitation Scanning (HIFEX) Microscopy for Live Cell Imaging Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34045785 Optimizing Channel Selection for Excitation-scanning Hyperspectral Imaging Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34045784 Optimization of Light Transmission Through an Excitation-scan Hyperspectral Mirror Array System Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34045783 A Spherical Mirror-based Illumination System for Fluorescence Excitation-Scanning Hyperspectral Imaging Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34045782 Hyperspectral Imaging Microscopy for Measurement of Localized Second Messenger Signals in Single Cells Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2019 | Pubmed ID: 34045781 Demystifying Autofluorescence with Excitation-scanning Hyperspectral Imaging Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2018 | Pubmed ID: 34092890 Colorectal Cancer Detection by Hyperspectral Imaging Using Fluorescence Excitation Scanning Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2018 | Pubmed ID: 34092889 Endoscopic Hyperspectral Imaging: Light Guide Optimization for Spectral Light Source Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2018 | Pubmed ID: 34092888 Applications and Assessment of an Excitation-scanning Hyperspectral Imaging System Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2018 | Pubmed ID: 31762531 Identifying Molecular Contributors to Autofluorescence of Neoplastic and Normal Colon Sections Using Excitation-scanning Hyperspectral Imaging Journal of Biomedical Optics. 12, 2018 | Pubmed ID: 30592190 Spectral Imaging of FRET-based Sensors Reveals Sustained CAMP Gradients in Three Spatial Dimensions Cytometry. Part A : the Journal of the International Society for Analytical Cytology. 10, 2018 | Pubmed ID: 30176184 Human ASIC1a Mediates Stronger Acid-induced Responses As Compared with Mouse ASIC1a FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2018 | Pubmed ID: 29447005 A Theoretical-experimental Methodology for Assessing the Sensitivity of Biomedical Spectral Imaging Platforms, Assays, and Analysis Methods Journal of Biophotonics. Jan, 2018 | Pubmed ID: 28485093 Optimization and Applications of an Excitation-scanning Hyperspectral Imaging System Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2017 | Pubmed ID: 34092887 Excitation-Scanning Hyperspectral Imaging As a Means to Discriminate Various Tissues Types Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2017 | Pubmed ID: 34092886 5D Imaging Approaches Reveal the Formation of Distinct Intracellular CAMP Spatial Gradients Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2017 | Pubmed ID: 34054188 Comparing Methods for Analysis of Biomedical Hyperspectral Image Data Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2017 | Pubmed ID: 34054187 Design of a Modified Endoscope Illuminator for Spectral Imaging of Colorectal Tissues Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2017 | Pubmed ID: 34045780 Hyperspectral Imaging Fluorescence Excitation Scanning for Detecting Colorectal Cancer: Pilot Study Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2016 | Pubmed ID: 34429564 Feasibility for Detection of Autofluorescent Signatures in Rat Organs Using a Novel Excitation-scanning Hyperspectral Imaging System Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2016 | Pubmed ID: 34131358 Excitation-Scanning Hyperspectral Imaging System for Microscopic and Endoscopic Applications Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2016 | Pubmed ID: 34092892 LED-based Endoscopic Light Source for Spectral Imaging Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2016 | Pubmed ID: 34054191 Three Dimensional Measurement of CAMP Gradients Using Hyperspectral Confocal Microscopy Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2016 | Pubmed ID: 34045789 Hyperspectral Imaging Fluorescence Excitation Scanning for Colon Cancer Detection Journal of Biomedical Optics. 10, 2016 | Pubmed ID: 27792808 Overcoming Limitations of FRET Measurements Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Apr, 2016 | Pubmed ID: 27101317 Estimating the Magnitude of Near-membrane PDE4 Activity in Living Cells American Journal of Physiology. Cell Physiology. Sep, 2015 | Pubmed ID: 26201952 Channel-based Reporters for CAMP Detection Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25783878 Automated Image Analysis of FRET Signals for Subcellular CAMP Quantification Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25783877 Sodium Entry Through Endothelial Store-operated Calcium Entry Channels: Regulation by Orai1 American Journal of Physiology. Cell Physiology. Feb, 2015 | Pubmed ID: 25428882 FRET: Signals Hidden Within the Noise Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2014 | Pubmed ID: 25241962 β-Agonist-mediated Relaxation of Airway Smooth Muscle is Protein Kinase A-dependent The Journal of Biological Chemistry. Aug, 2014 | Pubmed ID: 24973219 Excitation-scanning Hyperspectral Imaging Microscope Journal of Biomedical Optics. Apr, 2014 | Pubmed ID: 24727909 Can We Decipher the Information Content Contained Within Cyclic Nucleotide Signals? The Journal of General Physiology. Jan, 2014 | Pubmed ID: 24378904 Thin-film Tunable Filters for Hyperspectral Fluorescence Microscopy Journal of Biomedical Optics. Jan, 2014 | Pubmed ID: 24077519 Tunable Thin-film Optical Filters for Hyperspectral Microscopy Proceedings of SPIE--the International Society for Optical Engineering. Feb, 2013 | Pubmed ID: 34045788 Assessing FRET Using Spectral Techniques Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Oct, 2013 | Pubmed ID: 23929684 An Approach for Characterizing and Comparing Hyperspectral Microscopy Systems Sensors (Basel, Switzerland). Jul, 2013 | Pubmed ID: 23877125 Hyperspectral Imaging of FRET-based CGMP Probes Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23709027 Feedback Regulation of Cone Cyclic Nucleotide Channels by Phosphoinositides. Focus on "CNGA3 Achromatopsia-associated Mutation Potentiates the Phosphoinositide Sensitivity of Cone Photoreceptor CNG Channels by Altering Intersubunit Interactions" American Journal of Physiology. Cell Physiology. Jul, 2013 | Pubmed ID: 23677796 Calcineurin Regulates Homologous Desensitization of Natriuretic Peptide Receptor-A and Inhibits ANP-induced Testosterone Production in MA-10 Cells PloS One. 2012 | Pubmed ID: 22876290 A-kinase Anchoring Proteins Regulate Compartmentalized CAMP Signaling in Airway Smooth Muscle FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2012 | Pubmed ID: 22649031 Assessment of Cellular Mechanisms Contributing to CAMP Compartmentalization in Pulmonary Microvascular Endothelial Cells American Journal of Physiology. Cell Physiology. Mar, 2012 | Pubmed ID: 22116306 Hyperspectral Imaging Microscopy for Identification and Quantitative Analysis of Fluorescently-labeled Cells in Highly Autofluorescent Tissue Journal of Biophotonics. Jan, 2012 | Pubmed ID: 21987373 All Preconditioning-related G Protein-coupled Receptors Can Be Demonstrated in the Rabbit Cardiomyocyte Journal of Cardiovascular Pharmacology and Therapeutics. Jun, 2012 | Pubmed ID: 21828281 Inactivation of Multidrug Resistance Proteins Disrupts Both Cellular Extrusion and Intracellular Degradation of CAMP Molecular Pharmacology. Aug, 2011 | Pubmed ID: 21551375 A2B Adenosine Receptors Inhibit Superoxide Production from Mitochondrial Complex I in Rabbit Cardiomyocytes Via a Mechanism Sensitive to Pertussis Toxin British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21366548 PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21288894 Quantitative Modeling of GRK-mediated Beta2AR Regulation PLoS Computational Biology. Jan, 2010 | Pubmed ID: 20098494 Receptor Reserve Reflects Differential Intrinsic Efficacy Associated with Opioid Diastereomers Pharmacology, Biochemistry, and Behavior. May, 2009 | Pubmed ID: 19463265 Roles of GRK and PDE4 Activities in the Regulation of Beta2 Adrenergic Signaling The Journal of General Physiology. Apr, 2008 | Pubmed ID: 18347080 Cellular Mechanisms Underlying Prostaglandin-induced Transient CAMP Signals Near the Plasma Membrane of HEK-293 Cells American Journal of Physiology. Cell Physiology. Jan, 2007 | Pubmed ID: 16899551 세포 신호를 분석하는 통합 툴킷: 힘, 동작, 형태학 및 형광 Alyson Nguyen*1, Keith Battle*2,3, Sunita S. Paudel*2,3, Ningyong Xu2, Jessica Bell3, Linn Ayers3, Cassandra Chapman4, Ajay P. Singh5, Srinivas Palanki6, Thomas Rich3,7, Diego F. Alvarez8, Troy Stevens2,3, Dhananjay T. Tambe3,4,7 1Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama, 2Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, 3Center for Lung Biology, College of Medicine, University of South Alabama, 4William B. Burnsed Jr. Mechanical, Aerospace, and Biomedical Engineering Department, College of Engineering, University of South Alabama, 5Mitchell Cancer Institute, College of Medicine, University of South Alabama, 6Department of Chemical and Biomedical Engineering, West Virginia University, 7Department of Pharmacology, College of Medicine, University of South Alabama, 8Department of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University JoVE 63095 Biology 형광 신호를 효율적으로 구별하기 위한 여기-스캐닝 하이퍼스펙트럼 이미징 현미경 검사법 Joshua Deal1,2,3, Andrea Britain2,3, Thomas Rich2,3, Silas Leavesley1,2,3 1Department of Chemical and Biomolecular Engineering, University of South Alabama, 2Center for Lung Biology, University of South Alabama, 3Department of Pharmacology, University of South Alabama JoVE 59448 Engineering
세포 신호를 분석하는 통합 툴킷: 힘, 동작, 형태학 및 형광 Alyson Nguyen*1, Keith Battle*2,3, Sunita S. Paudel*2,3, Ningyong Xu2, Jessica Bell3, Linn Ayers3, Cassandra Chapman4, Ajay P. Singh5, Srinivas Palanki6, Thomas Rich3,7, Diego F. Alvarez8, Troy Stevens2,3, Dhananjay T. Tambe3,4,7 1Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama, 2Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, 3Center for Lung Biology, College of Medicine, University of South Alabama, 4William B. Burnsed Jr. Mechanical, Aerospace, and Biomedical Engineering Department, College of Engineering, University of South Alabama, 5Mitchell Cancer Institute, College of Medicine, University of South Alabama, 6Department of Chemical and Biomedical Engineering, West Virginia University, 7Department of Pharmacology, College of Medicine, University of South Alabama, 8Department of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University JoVE 63095 Biology
형광 신호를 효율적으로 구별하기 위한 여기-스캐닝 하이퍼스펙트럼 이미징 현미경 검사법 Joshua Deal1,2,3, Andrea Britain2,3, Thomas Rich2,3, Silas Leavesley1,2,3 1Department of Chemical and Biomolecular Engineering, University of South Alabama, 2Center for Lung Biology, University of South Alabama, 3Department of Pharmacology, University of South Alabama JoVE 59448 Engineering