Tomoki Chiba Graduate School of Life and Environmental Sciences University of Tsukuba Biography Publications Institution JoVE Articles Tomoki Chiba has not added a biography. If you are Tomoki Chiba and would like to personalize this page please email our Author Liaison for assistance. Publications Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction PLoS Genetics. Jan, 2017 | Pubmed ID: 28114340 CACUL1/CAC1 Attenuates P53 Activity Through PML Post-translational Modification Biochemical and Biophysical Research Communications. Jan, 2017 | Pubmed ID: 27889610 Structural Changes in Molluscan Community over a 15-Year Period Before and After the 2011 Great East Japan Earthquake and Subsequent Tsunami Around Matsushima Bay, Miyagi Prefecture, Northeastern Japan PloS One. 2016 | Pubmed ID: 27936182 USP15 Stabilizes the Transcription Factor Nrf1 in the Nucleus, Promoting the Proteasome Gene Expression Biochemical and Biophysical Research Communications. Sep, 2016 | Pubmed ID: 27416755 SCFFbl12 Increases P21Waf1/Cip1 Expression Level Through Atypical Ubiquitin Chain Synthesis Molecular and Cellular Biology. Aug, 2016 | Pubmed ID: 27215384 Proteasome Activators, PA28γ and PA200, Play Indispensable Roles in Male Fertility Scientific Reports. Mar, 2016 | Pubmed ID: 27003159 KIAA0368-deficiency Affects Disassembly of 26S Proteasome Under Oxidative Stress Condition Journal of Biochemistry. Jun, 2016 | Pubmed ID: 26802743 CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2 Scientific Reports. Aug, 2015 | Pubmed ID: 26238671 TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis Stem Cells and Development. May, 2015 | Pubmed ID: 25579647 Transcription Activator-like Effector Nuclease-mediated Transduction of Exogenous Gene into IL2RG Locus Scientific Reports. May, 2014 | Pubmed ID: 24853770 Role of Nuclear IκBs in Inflammation Regulation Biomolecular Concepts. Apr, 2013 | Pubmed ID: 25436575 Myeloma Overexpressed 2 (Myeov2) Regulates L11 Subnuclear Localization Through Nedd8 Modification PloS One. 2013 | Pubmed ID: 23776465 Acetylation-mediated Proteasomal Degradation of Core Histones During DNA Repair and Spermatogenesis Cell. May, 2013 | Pubmed ID: 23706739 Brap2 Regulates Temporal Control of NF-κB Localization Mediated by Inflammatory Response PloS One. 2013 | Pubmed ID: 23554956 Sepsis-induced Hypercytokinemia and Lymphocyte Apoptosis in Aging-accelerated Klotho Knockout Mice Shock (Augusta, Ga.). Mar, 2013 | Pubmed ID: 23364432 Reduction of Immunocompetent T Cells Followed by Prolonged Lymphopenia in Severe Sepsis in the Elderly Critical Care Medicine. Mar, 2013 | Pubmed ID: 23328259 Spermatogenesis Arrest Caused by Conditional Deletion of Hsp90α in Adult Mice Biology Open. Oct, 2012 | Pubmed ID: 23213375 Reciprocal Control of G1-phase Progression is Required for Th-POK/Runx3-mediated CD4/8 Thymocyte Cell Fate Decision Journal of Immunology (Baltimore, Md. : 1950). Nov, 2012 | Pubmed ID: 23018457 A Method for Inducing Antigen-specific IgG Production by in Vitro Immunization Journal of Immunological Methods. Dec, 2012 | Pubmed ID: 22974834 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 Smad7-deficient Mice Show Growth Retardation with Reduced Viability Journal of Biochemistry. Jun, 2012 | Pubmed ID: 22383537 IκBL, a Novel Member of the Nuclear IκB Family, Inhibits Inflammatory Cytokine Expression FEBS Letters. Nov, 2011 | Pubmed ID: 22024480 Cell Activation by CpG ODN Leads to Improved Electrofusion in Hybridoma Production Journal of Immunological Methods. Oct, 2011 | Pubmed ID: 21878337 Ubiquitin Ligase Activity of Cul3-KLHL7 Protein is Attenuated by Autosomal Dominant Retinitis Pigmentosa Causative Mutation The Journal of Biological Chemistry. Sep, 2011 | Pubmed ID: 21828050 PA28 and the Proteasome Immunosubunits Play a Central and Independent Role in the Production of MHC Class I-binding Peptides in Vivo European Journal of Immunology. Apr, 2011 | Pubmed ID: 21360704 Interplay of Transcription Factors in T-cell Differentiation and Function: the Role of Runx Immunology. Feb, 2011 | Pubmed ID: 21091910 Bioluminescence Assay for Detecting Cell Surface Membrane Protein Expression Assay and Drug Development Technologies. Feb, 2011 | Pubmed ID: 20836709 Induction of Th1-biased Cytokine Production by Alpha-carba-GalCer, a Neoglycolipid Ligand for NKT Cells International Immunology. Apr, 2010 | Pubmed ID: 20181652 The Mechanism of Poly-NEDD8 Chain Formation in Vitro Biochemical and Biophysical Research Communications. Apr, 2009 | Pubmed ID: 19245792 [Recognition of CD1d/glycolipid Antigen Complex by NKT Cells and Mechanisms in Immune Regulation] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Sep, 2008 | Pubmed ID: 21089371 PML Activates Transcription by Protecting HIPK2 and P300 from SCFFbx3-mediated Degradation Molecular and Cellular Biology. Dec, 2008 | Pubmed ID: 18809579 Hsp90-mediated Assembly of the 26 S Proteasome is Involved in Major Histocompatibility Complex Class I Antigen Processing The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18703510 A New Ubiquitin Ligase Involved in P57KIP2 Proteolysis Regulates Osteoblast Cell Differentiation EMBO Reports. Sep, 2008 | Pubmed ID: 18660753 Allele-selective Effect of PA28 in MHC Class I Antigen Processing Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008 | Pubmed ID: 18641301 Muscle RING-finger Protein-1 (MuRF1) As a Connector of Muscle Energy Metabolism and Protein Synthesis Journal of Molecular Biology. Mar, 2008 | Pubmed ID: 18222470 SCRAPPER-dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release Cell. Sep, 2007 | Pubmed ID: 17803915 Dioxin Receptor is a Ligand-dependent E3 Ubiquitin Ligase Nature. Mar, 2007 | Pubmed ID: 17392787 TBP-interacting Protein 120B (TIP120B)/cullin-associated and Neddylation-dissociated 2 (CAND2) Inhibits SCF-dependent Ubiquitination of Myogenin and Accelerates Myogenic Differentiation The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17242400 Direct Interactions Between NEDD8 and Ubiquitin E2 Conjugating Enzymes Upregulate Cullin-based E3 Ligase Activity Nature Structural & Molecular Biology. Feb, 2007 | Pubmed ID: 17206147 Isolation and Characterization of Phage-displayed Single Chain Antibodies Recognizing Nonreducing Terminal Mannose Residues. 1. A New Strategy for Generation of Anti-carbohydrate Antibodies Biochemistry. Jan, 2007 | Pubmed ID: 17198396 SUMO-specific Protease SUSP4 Positively Regulates P53 by Promoting Mdm2 Self-ubiquitination Nature Cell Biology. Dec, 2006 | Pubmed ID: 17086174 Decline of Striatal Dopamine Release in Parkin-deficient Mice Shown by Ex Vivo Autoradiography Journal of Neuroscience Research. Nov, 2006 | Pubmed ID: 16941649 [Physiological Role in Constitutive Autophagy] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Aug, 2006 | Pubmed ID: 16922430 [NEDD8 Conjugation System] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Aug, 2006 | Pubmed ID: 16922375 Analysis of Knock-out Mice to Determine the Role of HPC-1/syntaxin 1A in Expressing Synaptic Plasticity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006 | Pubmed ID: 16723534 Loss of Autophagy in the Central Nervous System Causes Neurodegeneration in Mice Nature. Jun, 2006 | Pubmed ID: 16625205 Depletion of Hsp90beta Induces Multiple Defects in B Cell Receptor Signaling The Journal of Biological Chemistry. Jun, 2006 | Pubmed ID: 16617057 The Ubiquitin-proteasome System Plays Essential Roles in Presenting an 8-mer CTL Epitope Expressed in APC to Corresponding CD8+ T Cells International Immunology. May, 2006 | Pubmed ID: 16569681 BTB Domain-containing Speckle-type POZ Protein (SPOP) Serves As an Adaptor of Daxx for Ubiquitination by Cul3-based Ubiquitin Ligase The Journal of Biological Chemistry. May, 2006 | Pubmed ID: 16524876 The Involvement of Immunoproteasomes in Induction of MHC Class I-restricted Immunity Targeting Toxoplasma SAG1 Microbes and Infection. Apr, 2006 | Pubmed ID: 16515877 Excess Peroxisomes Are Degraded by Autophagic Machinery in Mammals The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16332691 14-3-3eta is a Novel Regulator of Parkin Ubiquitin Ligase The EMBO Journal. Jan, 2006 | Pubmed ID: 16096643 [Regulation of the Protein Degradation Pathway by the Ubiquitin Family: Its Implication in Neurodegenerative Diseases] Rinsho Shinkeigaku = Clinical Neurology. Nov, 2005 | Pubmed ID: 16447778 In Vitro Systems for NEDD8 Conjugation by Ubc12 Methods in Enzymology. 2005 | Pubmed ID: 16275320 [Biology of the Reversible Protein Ubiquitination] Seikagaku. The Journal of Japanese Biochemical Society. Jun, 2005 | Pubmed ID: 16022430 Multiple Roles of Rbx1 in the VBC-Cul2 Ubiquitin Ligase Complex Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jul, 2005 | Pubmed ID: 15966899 Differential Expression Regulation of the Alpha and Beta Subunits of the PA28 Proteasome Activator in Mature Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2005 | Pubmed ID: 15944286 Common Anti-apoptotic Roles of Parkin and Alpha-synuclein in Human Dopaminergic Cells Biochemical and Biophysical Research Communications. Jun, 2005 | Pubmed ID: 15896322 Impairment of Starvation-induced and Constitutive Autophagy in Atg7-deficient Mice The Journal of Cell Biology. May, 2005 | Pubmed ID: 15866887 DDB2, the Xeroderma Pigmentosum Group E Gene Product, is Directly Ubiquitylated by Cullin 4A-based Ubiquitin Ligase Complex DNA Repair. May, 2005 | Pubmed ID: 15811626 Regulation of Anaphylactic Responses by Phosphatidylinositol Phosphate Kinase Type I {alpha} The Journal of Experimental Medicine. Mar, 2005 | Pubmed ID: 15767368 Ligand-dependent Switching of Ubiquitin-proteasome Pathways for Estrogen Receptor The EMBO Journal. Dec, 2004 | Pubmed ID: 15538384 Expression of HIV-1 Accessory Protein Vif is Controlled Uniquely to Be Low and Optimal by Proteasome Degradation Microbes and Infection. Jul, 2004 | Pubmed ID: 15374000 Oxidative Stress Sensor Keap1 Functions As an Adaptor for Cul3-based E3 Ligase to Regulate Proteasomal Degradation of Nrf2 Molecular and Cellular Biology. Aug, 2004 | Pubmed ID: 15282312 Ubiquitin-fusion Degradation Pathway Plays an Indispensable Role in Naked DNA Vaccination with a Chimeric Gene Encoding a Syngeneic Cytotoxic T Lymphocyte Epitope of Melanocyte and Green Fluorescent Protein Immunology. Aug, 2004 | Pubmed ID: 15270727 Cullin-based Ubiquitin Ligase and Its Control by NEDD8-conjugating System Current Protein & Peptide Science. Jun, 2004 | Pubmed ID: 15180522 A Novel Protein-conjugating System for Ufm1, a Ubiquitin-fold Modifier The EMBO Journal. May, 2004 | Pubmed ID: 15071506 Structural Basis of Sugar-recognizing Ubiquitin Ligase Nature Structural & Molecular Biology. Apr, 2004 | Pubmed ID: 14990996 The Fusion Oncoprotein PML-RARalpha Induces Endoplasmic Reticulum (ER)-associated Degradation of N-CoR and ER Stress The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14701861 Proteasome Activator PA28gamma-dependent Nuclear Retention and Degradation of Hepatitis C Virus Core Protein Journal of Virology. Oct, 2003 | Pubmed ID: 12970408 Fbs2 is a New Member of the E3 Ubiquitin Ligase Family That Recognizes Sugar Chains The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12939278 A Palmitoylated RING Finger Ubiquitin Ligase and Its Homologue in the Brain Membranes Journal of Neurochemistry. Aug, 2003 | Pubmed ID: 12859687 CHIP: a Quality-control E3 Ligase Collaborating with Molecular Chaperones The International Journal of Biochemistry & Cell Biology. May, 2003 | Pubmed ID: 12672450 Conditional Knockdown of Proteasomes Results in Cell-cycle Arrest and Enhanced Expression of Molecular Chaperones Hsp70 and Hsp40 in Chicken DT40 Cells The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12594202 E3 Ubiquitin Ligase That Recognizes Sugar Chains Nature. Jul, 2002 | Pubmed ID: 12140560 Two Distinct Pathways Mediated by PA28 and Hsp90 in Major Histocompatibility Complex Class I Antigen Processing The Journal of Experimental Medicine. Jul, 2002 | Pubmed ID: 12119343 Antagonistic Regulation of Myogenesis by Two Deubiquitinating Enzymes, UBP45 and UBP69 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2002 | Pubmed ID: 12107281 फ्लोरोसेंट जांच के उपयोग के संवर्धित न्यूरॉन्स में एंडोसोम और लियोसोम की क्षमताओं का मात्रा Fuminori Tsuruta1,2,3, Tomomi Okajima1, Sarasa Yano1, Tomoki Chiba1,2,3 1Graduate School of Life and Environmental Sciences, University of Tsukuba, 2PhD Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 3Life Science Center of Tsukuba Advanced Research Alliance (TARA), University of Tsukuba JoVE 55488 Neuroscience
फ्लोरोसेंट जांच के उपयोग के संवर्धित न्यूरॉन्स में एंडोसोम और लियोसोम की क्षमताओं का मात्रा Fuminori Tsuruta1,2,3, Tomomi Okajima1, Sarasa Yano1, Tomoki Chiba1,2,3 1Graduate School of Life and Environmental Sciences, University of Tsukuba, 2PhD Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 3Life Science Center of Tsukuba Advanced Research Alliance (TARA), University of Tsukuba JoVE 55488 Neuroscience