Vadim Cherezov The Bridge Institute University of Southern California Biography Publications Institution JoVE Articles Vadim Cherezov has not added a biography. If you are Vadim Cherezov and would like to personalize this page please email our Author Liaison for assistance. Publications Serial Femtosecond Crystallography of Membrane Proteins Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27553241 Serial Femtosecond Crystallography Datasets from G Protein-coupled Receptors Scientific Data. 2016 | Pubmed ID: 27479354 X-ray Laser Diffraction for Structure Determination of the Rhodopsin-arrestin Complex Scientific Data. 2016 | Pubmed ID: 27070998 The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR-Ligand Interactions Journal of Chemical Information and Modeling. Jan, 2016 | Pubmed ID: 26642258 Serial Femtosecond X-ray Diffraction of Enveloped Virus Microcrystals Structural Dynamics (Melville, N.Y.). Jul, 2015 | Pubmed ID: 26798819 Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase Nature Communications. 2015 | Pubmed ID: 26673816 The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor Structure (London, England : 1993). Dec, 2015 | Pubmed ID: 26526853 Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor The Journal of Biological Chemistry. Dec, 2015 | Pubmed ID: 26420482 Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase IUCrJ. Sep, 2015 | Pubmed ID: 26306196 Crystal Structure of Rhodopsin Bound to Arrestin by Femtosecond X-ray Laser Nature. Jul, 2015 | Pubmed ID: 26200343 A Novel Inert Crystal Delivery Medium for Serial Femtosecond Crystallography IUCrJ. Jul, 2015 | Pubmed ID: 26177184 Fluorescence Recovery After Photobleaching in Lipidic Cubic Phase (LCP-FRAP): A Precrystallization Assay for Membrane Proteins Methods in Enzymology. 2015 | Pubmed ID: 25950976 Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography Cell. May, 2015 | Pubmed ID: 25913193 Lipidic Cubic Phase Serial Millisecond Crystallography Using Synchrotron Radiation IUCrJ. Mar, 2015 | Pubmed ID: 25866654 Two Disparate Ligand-binding Sites in the Human P2Y1 Receptor Nature. Apr, 2015 | Pubmed ID: 25822790 GPCR Structure, Function, Drug Discovery and Crystallography: Report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014 Naunyn-Schmiedeberg's Archives of Pharmacology. Aug, 2015 | Pubmed ID: 25772061 Structural Basis for Bifunctional Peptide Recognition at Human δ-opioid Receptor Nature Structural & Molecular Biology. Mar, 2015 | Pubmed ID: 25686086 Structural Biology. Crystal Structure of the Chemokine Receptor CXCR4 in Complex with a Viral Chemokine Science (New York, N.Y.). Mar, 2015 | Pubmed ID: 25612609 Generic GPCR Residue Numbers - Aligning Topology Maps While Minding the Gaps Trends in Pharmacological Sciences. Jan, 2015 | Pubmed ID: 25541108 Two Classes of Cholesterol Binding Sites for the β2AR Revealed by Thermostability and NMR Biophysical Journal. Nov, 2014 | Pubmed ID: 25418299 Constitutive Phospholipid Scramblase Activity of a G Protein-coupled Receptor Nature Communications. 2014 | Pubmed ID: 25296113 Preparation of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography Nature Protocols. Sep, 2014 | Pubmed ID: 25122522 Structural Basis for Smoothened Receptor Modulation and Chemoresistance to Anticancer Drugs Nature Communications. 2014 | Pubmed ID: 25008467 Femtosecond Crystallography of Membrane Proteins in the Lipidic Cubic Phase Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jul, 2014 | Pubmed ID: 24914147 Agonist-bound Structure of the Human P2Y12 Receptor Nature. May, 2014 | Pubmed ID: 24784220 Allosteric Sodium in Class A GPCR Signaling Trends in Biochemical Sciences. May, 2014 | Pubmed ID: 24767681 Structure of the Human P2Y12 Receptor in Complex with an Antithrombotic Drug Nature. May, 2014 | Pubmed ID: 24670650 Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator Science (New York, N.Y.). Apr, 2014 | Pubmed ID: 24603153 Lipidic Cubic Phase Injector Facilitates Membrane Protein Serial Femtosecond Crystallography Nature Communications. 2014 | Pubmed ID: 24525480 Molecular Control of δ-opioid Receptor Signalling Nature. Feb, 2014 | Pubmed ID: 24413399 Functional Assay for T4 Lysozyme-engineered G Protein-coupled Receptors with an Ion Channel Reporter Structure (London, England : 1993). Jan, 2014 | Pubmed ID: 24268646 Serial Femtosecond Crystallography of G Protein-coupled Receptors Science (New York, N.Y.). Dec, 2013 | Pubmed ID: 24357322 The Role of a Sodium Ion Binding Site in the Allosteric Modulation of the A(2A) Adenosine G Protein-coupled Receptor Structure (London, England : 1993). Dec, 2013 | Pubmed ID: 24210756 Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex Science (New York, N.Y.). Sep, 2013 | Pubmed ID: 24030490 Structure-based Ligand Discovery Targeting Orthosteric and Allosteric Pockets of Dopamine Receptors Molecular Pharmacology. Dec, 2013 | Pubmed ID: 24021214 Structure of the Human Glucagon Class B G-protein-coupled Receptor Nature. Jul, 2013 | Pubmed ID: 23863937 Integrated Nonlinear Optical Imaging Microscope for On-axis Crystal Detection and Centering at a Synchrotron Beamline Journal of Synchrotron Radiation. Jul, 2013 | Pubmed ID: 23765294 Hydrogen Bonding of Cholesterol in the Lipidic Cubic Phase Langmuir : the ACS Journal of Surfaces and Colloids. Jun, 2013 | Pubmed ID: 23763339 Structure of the Human Smoothened Receptor Bound to an Antitumour Agent Nature. May, 2013 | Pubmed ID: 23636324 Towards Protein-crystal Centering Using Second-harmonic Generation (SHG) Microscopy Acta Crystallographica. Section D, Biological Crystallography. May, 2013 | Pubmed ID: 23633594 Structural Features for Functional Selectivity at Serotonin Receptors Science (New York, N.Y.). May, 2013 | Pubmed ID: 23519215 Structural Basis for Molecular Recognition at Serotonin Receptors Science (New York, N.Y.). May, 2013 | Pubmed ID: 23519210 The GPCR Network: a Large-scale Collaboration to Determine Human GPCR Structure and Function Nature Reviews. Drug Discovery. Jan, 2013 | Pubmed ID: 23237917 Structure-function of the G Protein-coupled Receptor Superfamily Annual Review of Pharmacology and Toxicology. 2013 | Pubmed ID: 23140243 电压门控 K + 通道孔隙中模块的封闭状态中的脂质膜的晶体结构。 The Journal of Biological Chemistry. Dec, 2012 | Pubmed ID: 23095758 GPCRs 钠离子的变构调节的结构基础。 Science (New York, N.Y.). Jul, 2012 | Pubmed ID: 22798613 Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-coupled Receptors Structure (London, England : 1993). Jun, 2012 | Pubmed ID: 22681902 Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. Coli and Enteropathogenic Y. Pseudotuberculosis Structure (London, England : 1993). Jul, 2012 | Pubmed ID: 22658748 Structure of the Nociceptin/orphanin FQ Receptor in Complex with a Peptide Mimetic Nature. 2012 | Pubmed ID: 22596163 Structure of the Human κ-opioid Receptor in Complex with JDTic Nature. May, 2012 | Pubmed ID: 22437504 G 蛋白偶联受体结构的模块性和多样性。 Trends in Pharmacological Sciences. Jan, 2012 | Pubmed ID: 22032986 气相化学还原使用混合甾醇洗涤剂束的类似 Bicelle 的体系结构的稳定。 Methods (San Diego, Calif.). Dec, 2011 | Pubmed ID: 22041719 脂质膜蛋白结晶过程的高吞吐量小角 X 射线散射矩阵的表征。 Methods (San Diego, Calif.). Dec, 2011 | Pubmed ID: 21903166 高分辨率结构 Ba3 细胞色素 C 氧化酶酶在油脂的环境中。 PloS One. 2011 | Pubmed ID: 21814577 膜蛋白结构研究的油脂立方相技术。 Current Opinion in Structural Biology. Aug, 2011 | Pubmed ID: 21775127 复杂多虑平人类组胺 H1 受体的结构。 Nature. Jul, 2011 | Pubmed ID: 21697825 血脂高能指南膜蛋白结晶自动化高吞吐量 LCP 收紧测定的发展。 Crystal Growth & Design. Apr, 2011 | Pubmed ID: 21660116 激动剂绑定人类 A2A 腺苷受体的结构。 Science (New York, N.Y.). Apr, 2011 | Pubmed ID: 21393508 人类多巴胺 D3 受体在 D2/D3 选择性拮抗剂具有复杂的结构。 Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 21097933 气相化学还原与小分子和循环肽拮抗剂 CXCR4 趋化因子的结构。 Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 20929726 人类 Beta2 肾上腺素能受体反受体激动剂和拮抗剂揭示的 X 射线晶体学的守恒的绑定模式。 Journal of the American Chemical Society. Aug, 2010 | Pubmed ID: 20669948 结构测定 GPCRs,与作为制药目标高潜力的膜蛋白家族的最新进展。 Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20665265 LCP-Tm: 测定,测量和了解膜蛋白膜环境中的稳定性。 Biophysical Journal. Apr, 2010 | Pubmed ID: 20409473 在油脂高能积分膜蛋白晶体的非线性光学成像。 Analytical Chemistry. Jan, 2010 | Pubmed ID: 20025250 筛选和归心微晶样品的人类膜蛋白与子 10 Microm 大小 X 射线同步辐射光束光栅型战略。 Journal of the Royal Society, Interface / the Royal Society. Oct, 2009 | Pubmed ID: 19535414 使用油脂高能的结晶膜蛋白。 Nature Protocols. 2009 | Pubmed ID: 19390528 绑定到 Beta2-肾上腺素能受体的全部和部分激动剂的分析表明跨膜螺旋 V 在特定激动剂的构象变化中的作用。 Journal of Molecular Recognition : JMR. Jul-Aug, 2009 | Pubmed ID: 19353579 LCP 收紧的预检细观结晶膜蛋白的测定。 Crystal Growth & Design. 2008 | Pubmed ID: 19234616 人类 A2A 腺苷受体的 2.6 埃晶体结构绑定到拮抗剂。 Science (New York, N.Y.). Nov, 2008 | Pubmed ID: 18832607 洞察的淀粉酶嗜热指认锌转运蛋白 CzrB 的行动模式。 Structure (London, England : 1993). Sep, 2008 | Pubmed ID: 18786400 具体胆固醇绑定站点的建立人类 Beta2-肾上腺素能受体的 2.8 A 结构。 Structure (London, England : 1993). Jun, 2008 | Pubmed ID: 18547522 细观晶体结构和对接模拟建议 OpcA 外膜黏附在替代蛋白多糖绑定网站。 Proteins. Apr, 2008 | Pubmed ID: 18076035 工程人类 Beta2-肾上腺素 G 蛋白偶联受体的高分辨率晶体结构。 Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 17962520 气相化学还原工程收益率 Beta2-肾上腺素能受体功能的高分辨率结构洞察。 Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 17962519 油脂高能膜蛋白结晶。使用 X 射线 Microdiffraction 的机理研究。 Faraday Discussions. 2007 | Pubmed ID: 17955811 结晶和可溶性域从淀粉酶嗜热的假定锌转运蛋白 CzrB 的初步的 X 射线衍射分析。 Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Aug, 2007 | Pubmed ID: 17671365 由磷脂的蚀性能研究控制光线通过金属微通道的通行。 The Journal of Physical Chemistry. B. Nov, 2006 | Pubmed ID: 17064131 胆固醇的不饱和 Phosphatidylethanolamines 分子组织: X 射线衍射和固态 2 H 核磁共振显示与磷脂酰胆碱的差异。 Journal of the American Chemical Society. Apr, 2006 | Pubmed ID: 16620109 移动的空间: 结晶肿油脂高能膜蛋白。 Journal of Molecular Biology. Apr, 2006 | Pubmed ID: 16490208 油脂高能与定制双层膜蛋白结晶。 Structure (London, England : 1993). Dec, 2004 | Pubmed ID: 15576026 从紊乱,集结与混沌血脂胆固醇订购。多不饱和脂质膜筏形成中的作用。 Chemistry and Physics of Lipids. Nov, 2004 | Pubmed ID: 15530450 脂质膜蛋白结晶过程的合理设计。 Journal of Structural Biology. Nov, 2004 | Pubmed ID: 15477097 结晶膜和可溶性蛋白含量油脂高能的机器人系统。 Acta Crystallographica. Section D, Biological Crystallography. Oct, 2004 | Pubmed ID: 15388926 二十二碳六烯酸含磷脂与胆固醇的相互作用: Microdomain/筏形成触发器吗? Biochemistry. Oct, 2003 | Pubmed ID: 14556634 细观膜蛋白结晶: 脂质类型定制的立方的阶段。 Biophysical Journal. Dec, 2002 | Pubmed ID: 12496106 太热,不能处理呢?脂质膜和高能同步辐射 X 射线损伤。 Journal of Synchrotron Radiation. Nov, 2002 | Pubmed ID: 12409619 膜胆固醇含量的控制。多价不饱和 (docosahexaenoate) 磷脂的作用。 Biochemistry. Oct, 2002 | Pubmed ID: 12369842 DiC 14-amidine/DNA 复杂的生物物理和基因转染的研究。 Biophysical Journal. Jun, 2002 | Pubmed ID: 12023234 多不饱和的细胞膜中的胆固醇的分子组织: Microdomain 形成。 Biophysical Journal. Jan, 2002 | Pubmed ID: 11751316 制备及脂质立方相反应蛋白微晶交付串行飞秒晶体 Andrii Ishchenko1,2, Vadim Cherezov1,2, Wei Liu3 1The Bridge Institute, University of Southern California, 2Department of Chemistry, University of Southern California, 3School of Molecular Sciences, Center for Applied Structural Discovery at the Biodesign Institute, Arizona State University Biochemistry 在油脂介孔膜蛋白的结晶 Wei Liu1, Vadim Cherezov1 1Molecular Biology, The Scripps Research Institute JoVE 2501 Biology
制备及脂质立方相反应蛋白微晶交付串行飞秒晶体 Andrii Ishchenko1,2, Vadim Cherezov1,2, Wei Liu3 1The Bridge Institute, University of Southern California, 2Department of Chemistry, University of Southern California, 3School of Molecular Sciences, Center for Applied Structural Discovery at the Biodesign Institute, Arizona State University Biochemistry
在油脂介孔膜蛋白的结晶 Wei Liu1, Vadim Cherezov1 1Molecular Biology, The Scripps Research Institute JoVE 2501 Biology