Valentina Kon Division of Pediatric Nephrology Department of Pediatrics Vanderbilt University Medical Center Biography Publications Institution JoVE Articles Valentina Kon has not added a biography. If you are Valentina Kon and would like to personalize this page please email our Author Liaison for assistance. Publications Intestinal Lymphatic Dysfunction in Kidney Disease Circulation Research. Apr, 2023 | Pubmed ID: 37104557 Novel Concepts in Nephron Sodium Transport: A Physiological and Clinical Perspective Advances in Kidney Disease and Health. Mar, 2023 | Pubmed ID: 36868728 Dicarbonyl-modified Lipoproteins Contribute to Proteinuric Kidney Injury JCI Insight. Nov, 2022 | Pubmed ID: 36125905 DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension Circulation Research. Aug, 2022 | Pubmed ID: 35862128 Inflammation, Lymphatics, and Cardiovascular Disease: Amplification by Chronic Kidney Disease Current Hypertension Reports. Oct, 2022 | Pubmed ID: 35727522 Podocyte-Related Mechanisms Underlying Survival Benefit of Long-Term Angiotensin Receptor Blocker International Journal of Molecular Sciences. May, 2022 | Pubmed ID: 35682697 Kidney Injury Causes Accumulation of Renal Sodium That Modulates Renal Lymphatic Dynamics International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35163352 Biotic Supplements in Patients With Chronic Kidney Disease: Meta-Analysis of Randomized Controlled Trials Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation. Jan, 2022 | Pubmed ID: 34666930 Rice Endosperm Protein Improves the Anti-Inflammatory Effects of High-Density Lipoprotein and Produces Lower Atherosclerotic Lesion Accelerated by the Renal Mass Reduction Than Casein in a Mouse Model Journal of the American Nutrition Association. 2022 | Pubmed ID: 34424818 High-Density Lipoproteins in Kidney Disease International Journal of Molecular Sciences. Jul, 2021 | Pubmed ID: 34360965 Myeloperoxidase-induced Modification of HDL by Isolevuglandins Inhibits Paraoxonase-1 Activity The Journal of Biological Chemistry. Sep, 2021 | Pubmed ID: 34331945 Kidney Injury-mediated Disruption of Intestinal Lymphatics Involves Dicarbonyl-modified Lipoproteins Kidney International. Jun, 2021 | Pubmed ID: 34102217 Increased Dishevelled Associated Activator of Morphogenesis 2, a New Podocyte-associated Protein, in Diabetic Nephropathy Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. May, 2021 | Pubmed ID: 33544843 Perioperative High Density Lipoproteins, Oxidative Stress, and Kidney Injury After Cardiac Surgery Journal of Lipid Research. 2021 | Pubmed ID: 33453220 Renal Lymphatic Vessel Dynamics American Journal of Physiology. Renal Physiology. Dec, 2020 | Pubmed ID: 33103446 Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity Nutrients. Jun, 2020 | Pubmed ID: 32629758 Pro-inflammatory HDL in Women with Obesity and Nonalcoholic Steatohepatitis Obesity Research & Clinical Practice. Jul - Aug, 2020 | Pubmed ID: 32595023 Inactivation of in Abcg2 Lineage-derived Cells Drives the Appearance of Polycystic Lesions and Fibrosis in the Adult Kidney American Journal of Physiology. Renal Physiology. 11, 2019 | Pubmed ID: 31461347 Urinary ApoAl: Novel Marker of Renal Disease? Pediatric Nephrology (Berlin, Germany). Nov, 2019 | Pubmed ID: 31402404 Urinary Apolipoprotein AI in Children with Kidney Disease Pediatric Nephrology (Berlin, Germany). Nov, 2019 | Pubmed ID: 31230128 Lipoprotein Modulation of Proteinuric Renal Injury Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2019 | Pubmed ID: 31019291 IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD Clinical Journal of the American Society of Nephrology : CJASN. 05, 2019 | Pubmed ID: 31015261 Dual Inhibition of Endothelial MiR-92a-3p and MiR-489-3p Reduces Renal Injury-associated Atherosclerosis Atherosclerosis. Mar, 2019 | Pubmed ID: 30731284 Kidney As Modulator and Target of "good/bad" HDL Pediatric Nephrology (Berlin, Germany). Oct, 2019 | Pubmed ID: 30291429 Chronic Kidney Disease Alters Lipid Trafficking and Inflammatory Responses in Macrophages: Effects of Liver X Receptor Agonism BMC Nephrology. Jan, 2018 | Pubmed ID: 29374468 Net Cholesterol Efflux Capacity of HDL Enriched Serum and Coronary Atherosclerosis in Rheumatoid Arthritis IJC Metabolic & Endocrine. Dec, 2016 | Pubmed ID: 28243578 Kidneys: Key Modulators of High-density Lipoprotein Levels and Function Current Opinion in Nephrology and Hypertension. May, 2016 | Pubmed ID: 27008596 Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis Arthritis & Rheumatology (Hoboken, N.J.). Sep, 2016 | Pubmed ID: 26991245 Atherosclerosis Following Renal Injury is Ameliorated by Pioglitazone and Losartan Via Macrophage Phenotype Atherosclerosis. Sep, 2015 | Pubmed ID: 26184694 Residual Cardiovascular Risk in Chronic Kidney Disease: Role of High-density Lipoprotein Archives of Medical Research. Jul, 2015 | Pubmed ID: 26009251 Dysfunctional High-density Lipoproteins in Children with Chronic Kidney Disease Metabolism: Clinical and Experimental. Feb, 2015 | Pubmed ID: 25467845 Vitronectin-binding PAI-1 Protects Against the Development of Cardiac Fibrosis Through Interaction with Fibroblasts Laboratory Investigation; a Journal of Technical Methods and Pathology. Jun, 2014 | Pubmed ID: 24687120 Angiotensin-induced Abdominal Aortic Aneurysms in Hypercholesterolemic Mice: Role of Serum Cholesterol and Temporal Effects of Exposure PloS One. 2014 | Pubmed ID: 24465413 Chronic Kidney Disease Induced Dysfunction of High Density Lipoprotein Clinical and Experimental Nephrology. Apr, 2014 | Pubmed ID: 24018401 Thymosin β4 and Its Degradation Product, Ac-SDKP, Are Novel Reparative Factors in Renal Fibrosis Kidney International. Dec, 2013 | Pubmed ID: 23739235 Importance of High-density Lipoprotein Quality: Evidence from Chronic Kidney Disease Current Opinion in Nephrology and Hypertension. May, 2013 | Pubmed ID: 23470818 Dysfunctional High-density Lipoprotein in Patients on Chronic Hemodialysis Journal of the American College of Cardiology. Dec, 2012 | Pubmed ID: 23141484 Maturational Regression of Glomeruli Determines the Nephron Population in Normal Mice Pediatric Research. Sep, 2012 | Pubmed ID: 22717689 Mineralocorticoid Receptor Blocker Protects Against Podocyte-Dependent Glomerulosclerosis Nephron Extra. Jan, 2012 | Pubmed ID: 22479265 Benzo[a]pyrene Potentiates the Pathogenesis of Abdominal Aortic Aneurysms in Apolipoprotein E Knockout Mice Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2012 | Pubmed ID: 22415081 Protective Effects of PPARγ Agonist in Acute Nephrotic Syndrome Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Jan, 2012 | Pubmed ID: 21565943 Macrophage Polarization by Angiotensin II-type 1 Receptor Aggravates Renal Injury-acceleration of Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2011 | Pubmed ID: 21979434 Podocyte Injury Damages Other Podocytes Journal of the American Society of Nephrology : JASN. Jul, 2011 | Pubmed ID: 21719786 Quantitative Estimates of the Variability of in Vivo Sonographic Measurements of the Mouse Aorta for Studies of Abdominal Aortic Aneurysms and Related Arterial Diseases Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Jun, 2011 | Pubmed ID: 21632991 Induction of Podocyte-derived VEGF Ameliorates Podocyte Injury and Subsequent Abnormal Glomerular Development Caused by Puromycin Aminonucleoside Pediatric Research. Jul, 2011 | Pubmed ID: 21451433 Angiotensin Type 1 Receptor Modulates Macrophage Polarization and Renal Injury in Obesity American Journal of Physiology. Renal Physiology. May, 2011 | Pubmed ID: 21367915 Oral Activated Charcoal Adsorbent (AST-120) Ameliorates Extent and Instability of Atherosclerosis Accelerated by Kidney Disease in Apolipoprotein E-deficient Mice Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Aug, 2011 | Pubmed ID: 21245127 Glomerular Sclerosis is Prevented During Urinary Tract Obstruction Due to Podocyte Protection American Journal of Physiology. Renal Physiology. Mar, 2011 | Pubmed ID: 21177778 Atherosclerosis in Chronic Kidney Disease: the Role of Macrophages Nature Reviews. Nephrology. Jan, 2011 | Pubmed ID: 21102540 Scope and Mechanisms of Obesity-related Renal Disease Current Opinion in Nephrology and Hypertension. May, 2010 | Pubmed ID: 20134323 Angiotensin Type 2 Receptor Actions Contribute to Angiotensin Type 1 Receptor Blocker Effects on Kidney Fibrosis American Journal of Physiology. Renal Physiology. Mar, 2010 | Pubmed ID: 20042458 Fibrinogen That Appears in Bowman's Space of Proteinuric Kidneys in Vivo Activates Podocyte Toll-like Receptors 2 and 4 in Vitro Nephron. Experimental Nephrology. 2010 | Pubmed ID: 19887845 Renal Dysfunction Potentiates Foam Cell Formation by Repressing ABCA1 Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2009 | Pubmed ID: 19667109 Mechanisms for Increased Cardiovascular Disease in Chronic Kidney Dysfunction Current Opinion in Nephrology and Hypertension. May, 2009 | Pubmed ID: 19374004 Inhibition of 11beta-hydroxysteroid Dehydrogenase Type II Selectively Blocks the Tumor COX-2 Pathway and Suppresses Colon Carcinogenesis in Mice and Humans The Journal of Clinical Investigation. Apr, 2009 | Pubmed ID: 19307727 Angiotensin Inhibition Decreases Progression of Advanced Atherosclerosis and Stabilizes Established Atherosclerotic Plaques Journal of the American Society of Nephrology : JASN. Aug, 2007 | Pubmed ID: 17634441 Antiatherogenic Effects of Angiotensin Receptor Antagonism in Mild Renal Dysfunction Journal of the American Society of Nephrology : JASN. Feb, 2006 | Pubmed ID: 16371432 Transiently Heightened Angiotensin II Has Distinct Effects on Atherosclerosis and Aneurysm Formation in Hyperlipidemic Mice Atherosclerosis. Feb, 2006 | Pubmed ID: 16023123 Proteomic Patterns and Prediction of Glomerulosclerosis and Its Mechanisms Journal of the American Society of Nephrology : JASN. Oct, 2005 | Pubmed ID: 16079267 Conditional Knockout of Macrophage PPARgamma Increases Atherosclerosis in C57BL/6 and Low-density Lipoprotein Receptor-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2005 | Pubmed ID: 15947238 Angiotensin in Atherosclerosis Current Opinion in Nephrology and Hypertension. May, 2004 | Pubmed ID: 15073487 Absence of Angiotensin II Type 1 Receptor in Bone Marrow-derived Cells is Detrimental in the Evolution of Renal Fibrosis The Journal of Clinical Investigation. Dec, 2002 | Pubmed ID: 12488436 בידוד צואה מורין והשתלת מיקרוביוטה Jeanne A. Ishimwe1, Jianyong Zhong2,3, Valentina Kon2, Annet Kirabo1 1Division of Clinical Pharmacology, Department of Medicine Vanderbilt University Medical Center and Department of Molecular Physiology and Biophysics, Vanderbilt University, 2Division of Pediatric Nephrology Department of Pediatrics, Vanderbilt University Medical Center, 3Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center JoVE 64310 Immunology and Infection
בידוד צואה מורין והשתלת מיקרוביוטה Jeanne A. Ishimwe1, Jianyong Zhong2,3, Valentina Kon2, Annet Kirabo1 1Division of Clinical Pharmacology, Department of Medicine Vanderbilt University Medical Center and Department of Molecular Physiology and Biophysics, Vanderbilt University, 2Division of Pediatric Nephrology Department of Pediatrics, Vanderbilt University Medical Center, 3Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center JoVE 64310 Immunology and Infection