Wen-Tsan Chang The Institute of Basic Medical Sciences, College of Medicine National Cheng Kung University Biography Publications Institution JoVE Articles Wen-Tsan Chang has not added a biography. If you are Wen-Tsan Chang and would like to personalize this page please email our Author Liaison for assistance. Publications The Decrease of Glycolytic Enzyme Hexokinase 1 Accelerates Tumor Malignancy Via Deregulating Energy Metabolism but Sensitizes Cancer Cells to 2-deoxyglucose Inhibition Oncotarget. Apr, 2018 | Pubmed ID: 29721175 Decreased Succinate Dehydrogenase B in Human Hepatocellular Carcinoma Accelerates Tumor Malignancy by Inducing the Warburg Effect Scientific Reports. Feb, 2018 | Pubmed ID: 29449614 Apoptotic and Nonapoptotic Activities of Pterostilbene Against Cancer International Journal of Molecular Sciences. Jan, 2018 | Pubmed ID: 29346311 Increased Risk of Brain Cancer Incidence in Stroke Patients: a Clinical Case Series, Population-based and Longitudinal Follow-up Study Oncotarget. Dec, 2017 | Pubmed ID: 29312585 Pterostilbene Prevents AKT-ERK Axis-mediated Polymerization of Surface Fibronectin on Suspended Lung Cancer Cells Independently of Apoptosis and Suppresses Metastasis Journal of Hematology & Oncology. 03, 2017 | Pubmed ID: 28327179 Graphene Quantum Dots Conjugated with Polymers for Two-photon Properties Under Two-photon Excitation Nanoscale. Sep, 2016 | Pubmed ID: 27722374 Dynamic Evolution of D-dimer Level in Cerebrospinal Fluid Predicts Poor Outcome in Patients with Spontaneous Intracerebral Hemorrhage Combined with Intraventricular Hemorrhage Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Jul, 2016 | Pubmed ID: 27050917 Cyclic Stretch Facilitates Myogenesis in C2C12 Myoblasts and Rescues Thiazolidinedione-Inhibited Myotube Formation Frontiers in Bioengineering and Biotechnology. 2016 | Pubmed ID: 27047938 Effect of Size-Dependent Photodestructive Efficacy by Gold Nanomaterials with Multiphoton Laser ACS Applied Materials & Interfaces. Aug, 2015 | Pubmed ID: 26172073 Association Between Mechanical Ventilation and Neurodevelopmental Disorders in a Nationwide Cohort of Extremely Low Birth Weight Infants Research in Developmental Disabilities. Jul, 2014 | Pubmed ID: 24769371 Construction of Simple and Efficient SiRNA Validation Systems for Screening and Identification of Effective RNAi-targeted Sequences from Mammalian Genes Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24233788 Upregulation of Tissue Factor by Activated Stat3 Contributes to Malignant Pleural Effusion Generation Via Enhancing Tumor Metastasis and Vascular Permeability in Lung Adenocarcinoma PloS One. 2013 | Pubmed ID: 24086497 Propolis Inhibits TGF-β1-induced Epithelial-mesenchymal Transition in Human Alveolar Epithelial Cells Via PPARγ Activation International Immunopharmacology. Mar, 2013 | Pubmed ID: 23328619 Loss of the Respiratory Enzyme Citrate Synthase Directly Links the Warburg Effect to Tumor Malignancy Scientific Reports. 2012 | Pubmed ID: 23139858 ACSL3 and GSK-3β Are Essential for Lipid Upregulation Induced by Endoplasmic Reticulum Stress in Liver Cells Journal of Cellular Biochemistry. Mar, 2011 | Pubmed ID: 21328461 Signal Transducer and Activator of Transcription 3 Activation Up-regulates Interleukin-6 Autocrine Production: a Biochemical and Genetic Study of Established Cancer Cell Lines and Clinical Isolated Human Cancer Cells Molecular Cancer. Dec, 2010 | Pubmed ID: 21122157 Hepatitis B Virus Surface Antigen Interacts with Acid Alpha-glucosidase and Alters Glycogen Metabolism Hepatology Research : the Official Journal of the Japan Society of Hepatology. Jun, 2010 | Pubmed ID: 20618459 Identification and Characterization of the Mitochondrial Targeting Sequence and Mechanism in Human Citrate Synthase Journal of Cellular Biochemistry. Aug, 2009 | Pubmed ID: 19479947 Caspase-3 Enhances Lung Metastasis and Cell Migration in a Protease-independent Mechanism Through the ERK Pathway International Journal of Cancer. Sep, 2008 | Pubmed ID: 18623086 Ceramide Induces P38 MAPK and JNK Activation Through a Mechanism Involving a Thioredoxin-interacting Protein-mediated Pathway Blood. Apr, 2008 | Pubmed ID: 18270325 Construction of Simple and Efficient DNA Vector-based Short Hairpin RNA Expression Systems for Specific Gene Silencing in Mammalian Cells Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 18314586 A Tightly Regulated and Reversibly Inducible SiRNA Expression System for Conditional RNAi-mediated Gene Silencing in Mammalian Cells The Journal of Gene Medicine. Jul, 2007 | Pubmed ID: 17486668 Deregulation of AP-1 Proteins in Collagen Gel-induced Epithelial Cell Apoptosis Mediated by Low Substratum Rigidity The Journal of Biological Chemistry. Jan, 2007 | Pubmed ID: 17085440 Inhibition of Cell Migration by Autophosphorylated Mammalian Sterile 20-like Kinase 3 (MST3) Involves Paxillin and Protein-tyrosine Phosphatase-PEST The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17046825 A Novel SiRNA Validation System for Functional Screening and Identification of Effective RNAi Probes in Mammalian Cells Biochemical and Biophysical Research Communications. Aug, 2006 | Pubmed ID: 16793020 A Novel Bidirectional Expression System for Simultaneous Expression of Both the Protein-coding Genes and Short Hairpin RNAs in Mammalian Cells Biochemical and Biophysical Research Communications. Jan, 2006 | Pubmed ID: 16337609 Association of CD14 Promoter Polymorphisms and Soluble CD14 Levels in Mite Allergen Sensitization of Children in Taiwan Journal of Human Genetics. 2006 | Pubmed ID: 16292464 Toll-like Receptor 4 Plays an Anti-HBV Role in a Murine Model of Acute Hepatitis B Virus Expression World Journal of Gastroenterology. Nov, 2005 | Pubmed ID: 16425356 Therapeutic Inhibition of Hepatitis B Virus Surface Antigen Expression by RNA Interference Biochemical and Biophysical Research Communications. Oct, 2005 | Pubmed ID: 16153600 LrrA, a Novel Leucine-rich Repeat Protein Involved in Cytoskeleton Remodeling, is Required for Multicellular Morphogenesis in Dictyostelium Discoideum Developmental Biology. Sep, 2005 | Pubmed ID: 16051212 Bcl-2 Rescues Ceramide- and Etoposide-induced Mitochondrial Apoptosis Through Blockage of Caspase-2 Activation The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15817479 Simple and Efficient DNA Vector-based RNAi Systems in Mammalian Cells Biochemical and Biophysical Research Communications. Apr, 2005 | Pubmed ID: 15781231 Streptococcal Pyrogenic Exotoxin B-induced Apoptosis in A549 Cells is Mediated by a Receptor- and Mitochondrion-dependent Pathway Infection and Immunity. Dec, 2004 | Pubmed ID: 15557629 Endoplasmic Reticulum Stress Stimulates the Expression of Cyclooxygenase-2 Through Activation of NF-kappaB and Pp38 Mitogen-activated Protein Kinase The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15319438 Sequential Caspase-2 and Caspase-8 Activation Upstream of Mitochondria During Ceramideand Etoposide-induced Apoptosis The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15262979 Disruption of the Peroxisomal Citrate Synthase CshA Affects Cell Growth and Multicellular Development in Dictyostelium Discoideum Molecular Microbiology. Jul, 2004 | Pubmed ID: 15225305 Pre-S Mutant Surface Antigens in Chronic Hepatitis B Virus Infection Induce Oxidative Stress and DNA Damage Carcinogenesis. Oct, 2004 | Pubmed ID: 15180947 The Role of Inducible Nitric Oxide Synthase in a Murine Acute Hepatitis B Virus (HBV) Infection Model Induced by Hydrodynamics-based in Vivo Transfection of HBV-DNA Journal of Hepatology. Nov, 2003 | Pubmed ID: 14568268 De oprichting van een Long kolonisatie Assay voor het circulerende Tumor visualisatie van de cel in de weefsels van de longen Tsung-Cheng Lin1, Ying-Chih Liao2, Wen-Tsan Chang1,2, Cheng-Han Yang1, Li-Hsin Cheng1, Megan Cheng3, Hung-Chi Cheng1,2 1The Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 3Trauma Office, Children's National Health System JoVE 56761 Cancer Research
De oprichting van een Long kolonisatie Assay voor het circulerende Tumor visualisatie van de cel in de weefsels van de longen Tsung-Cheng Lin1, Ying-Chih Liao2, Wen-Tsan Chang1,2, Cheng-Han Yang1, Li-Hsin Cheng1, Megan Cheng3, Hung-Chi Cheng1,2 1The Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 3Trauma Office, Children's National Health System JoVE 56761 Cancer Research