Wolfgang E. Thasler Department of Surgery Grosshadern Hospital, Munich Biography Publications Institution JoVE Articles Wolfgang E. Thasler has not added a biography. If you are Wolfgang E. Thasler and would like to personalize this page please email our Author Liaison for assistance. Publications Recent Advances in 2D and 3D in Vitro Systems Using Primary Hepatocytes, Alternative Hepatocyte Sources and Non-parenchymal Liver Cells and Their Use in Investigating Mechanisms of Hepatotoxicity, Cell Signaling and ADME Archives of Toxicology. Aug, 2013 | Pubmed ID: 23974980 High Throughput Transcriptome Analysis of Lipid Metabolism in Syrian Hamster Liver in Absence of an Annotated Genome BMC Genomics. 2013 | Pubmed ID: 23575280 Clinical Outcome of IBD-associated Versus Sporadic Colorectal Cancer: a Matched-pair Analysis Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. May, 2013 | Pubmed ID: 23475629 Effect of GLP1R Agonists Taspoglutide and Liraglutide on Primary Thyroid C-cells from Rodent and Man Journal of Molecular Endocrinology. Jun, 2013 | Pubmed ID: 23463748 Biobanking for Research in Surgery: Are Surgeons in Charge for Advancing Translational Research or Mere Assistants in Biomaterial and Data Preservation? Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Apr, 2013 | Pubmed ID: 23430290 RNA Stability in Human Liver: Comparison of Different Processing Times, Temperatures and Methods Molecular Biotechnology. Jan, 2013 | Pubmed ID: 22271457 Rectal Prolapse Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Dec, 2012 | Pubmed ID: 23054898 Expression and Function of the Atypical Cadherin FAT1 in Chronic Liver Disease Biochemical and Biophysical Research Communications. Sep, 2012 | Pubmed ID: 22959770 Hop Bitter Acids Exhibit Anti-fibrogenic Effects on Hepatic Stellate Cells in Vitro Experimental and Molecular Pathology. Apr, 2012 | Pubmed ID: 22146696 Human Hepatocytes: Isolation, Culture, and Quality Procedures Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22057448 [Surgical Options for Inguinal Hernia Repair] MMW Fortschritte Der Medizin. Dec, 2011 | Pubmed ID: 22308590 Novel Surgical Technique for Complete Traumatic Rupture of the Pancreas: A Case Report Journal of Medical Case Reports. 2011 | Pubmed ID: 21917159 Inferring Statin-induced Gene Regulatory Relationships in Primary Human Hepatocytes Bioinformatics (Oxford, England). Sep, 2011 | Pubmed ID: 21757465 Pulmonary Sclerosing Hemangioma in a 21-year-old Male with Metastatic Hereditary Non-polyposis Colorectal Cancer: Report of a Case World Journal of Surgical Oncology. 2011 | Pubmed ID: 21645337 A Systems Biology Approach to Dynamic Modeling and Inter-subject Variability of Statin Pharmacokinetics in Human Hepatocytes BMC Systems Biology. 2011 | Pubmed ID: 21548957 Cell Therapeutic Options in Liver Diseases: Cell Types, Medical Devices and Regulatory Issues Journal of Materials Science. Materials in Medicine. May, 2011 | Pubmed ID: 21461918 Wilhelm Tell's Failure: Surgical Management and Follow Up of a Transcranial Compound Bow Injury in a Two Year Old Child Clinical Neurology and Neurosurgery. Jul, 2011 | Pubmed ID: 21376457 Augmenter of Liver Regeneration (ALR) Protects Human Hepatocytes Against Apoptosis Biochemical and Biophysical Research Communications. Jan, 2011 | Pubmed ID: 21108930 The Formal Requirements of Algorithms and Their Implications in Clinical Medicine and Quality Management Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Jan, 2011 | Pubmed ID: 21042918 Description and Evaluation of a Bench Porcine Model for Teaching Surgical Residents Vascular Anastomosis Skills BMC Research Notes. 2010 | Pubmed ID: 20626856 Profiling Induction of Cytochrome P450 Enzyme Activity by Statins Using a New Liquid Chromatography-tandem Mass Spectrometry Cocktail Assay in Human Hepatocytes Drug Metabolism and Disposition: the Biological Fate of Chemicals. Sep, 2010 | Pubmed ID: 20551241 Cell Cycle Progression or Translation Control is Not Essential for Vesicular Stomatitis Virus Oncolysis of Hepatocellular Carcinoma PloS One. 2010 | Pubmed ID: 20539760 Genetic Inactivation of the Fanconi Anemia Gene FANCC Identified in the Hepatocellular Carcinoma Cell Line HuH-7 Confers Sensitivity Towards DNA-interstrand Crosslinking Agents Molecular Cancer. 2010 | Pubmed ID: 20509860 Neohepatocytes from Alcoholics and Controls Express Hepatocyte Markers and Display Reduced Fibrogenic TGF-ß/Smad3 Signaling: Advantage for Cell Transplantation? Alcoholism, Clinical and Experimental Research. Apr, 2010 | Pubmed ID: 20102559 Determinants of Morbidity and Survival After Elective Non-curative Resection of Stage IV Colon and Rectal Cancer International Journal of Colorectal Disease. Sep, 2009 | Pubmed ID: 19495779 Inhibition of the IFN-beta Response in Hepatocellular Carcinoma by Alternative Spliced Isoform of IFN Regulatory Factor-3 Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2008 | Pubmed ID: 18781139 Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells After LPS Challenge Molecular Medicine (Cambridge, Mass.). Jan-Feb, 2008 | Pubmed ID: 18037968 How Safe and Effective is Hepatic Resection for Patients with Noncolorectal Nonendocrine Liver Metastasis? Nature Clinical Practice. Gastroenterology & Hepatology. Jun, 2007 | Pubmed ID: 17489087 P60-c-src Suppresses Apoptosis Through Inhibition of Caspase 8 Activation in Hepatoma Cells, but Not in Primary Hepatocytes Journal of Hepatology. Apr, 2007 | Pubmed ID: 17224200 IL-22-mediated Liver Cell Regeneration is Abrogated by SOCS-1/3 Overexpression in Vitro American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2007 | Pubmed ID: 17204547 Human Tissue for in Vitro Research As an Alternative to Animal Experiments: a Charitable "honest Broker" Model to Fulfil Ethical and Legal Regulations and to Protect Research Participants Alternatives to Laboratory Animals : ATLA. Aug, 2006 | Pubmed ID: 16945006 Regulation of Polyamine Synthesis in Human Hepatocytes by Hepatotrophic Factor Augmenter of Liver Regeneration Biochemical and Biophysical Research Communications. Jun, 2006 | Pubmed ID: 16677602 Repression of Cytochrome P450 Activity in Human Hepatocytes in Vitro by a Novel Hepatotrophic Factor, Augmenter of Liver Regeneration The Journal of Pharmacology and Experimental Therapeutics. Feb, 2006 | Pubmed ID: 16214878 Fourth Meeting of the European Network of Research Tissue Banks - Future Strategy to Increase Collaborations in the Supply of Human Tissue for Biomedical Research Cell and Tissue Banking. 2005 | Pubmed ID: 15909101 LPS-mediated NFkappaB Activation Varies Between Activated Human Hepatic Stellate Cells from Different Donors Biochemical and Biophysical Research Communications. Dec, 2004 | Pubmed ID: 15522218 Charitable State-Controlled Foundation Human Tissue and Cell Research: Ethic and Legal Aspects in the Supply of Surgically Removed Human Tissue For Research in the Academic and Commercial Sector in Germany Cell and Tissue Banking. 2003 | Pubmed ID: 15256870 A Novel MCP-1 Gene Polymorphism is Associated with Hepatic MCP-1 Expression and Severity of HCV-related Liver Disease Gastroenterology. Oct, 2003 | Pubmed ID: 14517792 Cellular Damage to Human Hepatocytes Through Repeated Application of 5-aminolevulinic Acid Journal of Hepatology. Apr, 2003 | Pubmed ID: 12663240 Polyamine Levels of Human Colorectal Adenocarcinomas Are Correlated with Tumor Stage and Grade International Journal of Colorectal Disease. Nov, 2002 | Pubmed ID: 12355213 Isolement des hépatocytes humains par un deux-étape collagénase procédure de perfusion Serene M.L. Lee1,2, Celine Schelcher1, Maresa Demmel2,3, Maria Hauner3, Wolfgang E. Thasler4 1Experimental Surgical Research, Grosshadern Hospital, Munich, 2Center for Liver Cell Research, Grosshadern Hospital, Munich, 3Hepacult LLC, Regensburg, 4Department of Surgery, Grosshadern Hospital, Munich JoVE 50615 Biology
Isolement des hépatocytes humains par un deux-étape collagénase procédure de perfusion Serene M.L. Lee1,2, Celine Schelcher1, Maresa Demmel2,3, Maria Hauner3, Wolfgang E. Thasler4 1Experimental Surgical Research, Grosshadern Hospital, Munich, 2Center for Liver Cell Research, Grosshadern Hospital, Munich, 3Hepacult LLC, Regensburg, 4Department of Surgery, Grosshadern Hospital, Munich JoVE 50615 Biology