Wolfram-Hubertus Zimmermann Institute of Pharmacology and Toxicology University Medical Center Goettingen Biography Publications Institution JoVE Articles Wolfram-Hubertus Zimmermann has not added a biography. If you are Wolfram-Hubertus Zimmermann and would like to personalize this page please email our Author Liaison for assistance. Publications Establishment of Two Homozygous CRISPR Interference (CRISPRi) Knock-in Human Induced Pluripotent Stem Cell (hiPSC) Lines for Titratable Endogenous Gene Repression Stem Cell Research. Jul, 2021 | Pubmed ID: 34343828 Engineered Heart Muscle Models in Phenotypic Drug Screens Handbook of Experimental Pharmacology. 2021 | Pubmed ID: 33136187 Editorial Commentary: Challenges to Heart Repair with Pluripotent Stem Cell-derived Cardiomyocytes Trends in Cardiovascular Medicine. 02, 2021 | Pubmed ID: 32276084 Generation of Homozygous CRISPRa Human Induced Pluripotent Stem Cell (hiPSC) Lines for Sustained Endogenous Gene Activation Stem Cell Research. 10, 2020 | Pubmed ID: 33038615 Developmental GABA Polarity Switch and Neuronal Plasticity in Bioengineered Neuronal Organoids Nature Communications. 07, 2020 | Pubmed ID: 32728089 KLF15-Wnt-Dependent Cardiac Reprogramming Up-Regulates SHISA3 in the Mammalian Heart Journal of the American College of Cardiology. 10, 2019 | Pubmed ID: 31582141 Physics Meets Medicine - At the Heart of Active Matter Progress in Biophysics and Molecular Biology. 07, 2019 | Pubmed ID: 30980833 Cardiac Macrotissues-on-a-plate Models for Phenotypic Drug Screens Advanced Drug Delivery Reviews. 02, 2019 | Pubmed ID: 30902615 Agonistic and Antagonistic Roles of Fibroblasts and Cardiomyocytes on Viscoelastic Stiffening of Engineered Human Myocardium Progress in Biophysics and Molecular Biology. 07, 2019 | Pubmed ID: 30553553 A Scale Model of the Human Ventricle Nature Biomedical Engineering. 12, 2018 | Pubmed ID: 31015732 Engineered Nanoparticles Prevent Dilation of Abdominal Aortic Aneurysms Journal of the American College of Cardiology. 11, 2018 | Pubmed ID: 30466518 Highlighting the Field of Cardiovascular Regenerative Medicine Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2018 | Pubmed ID: 29934254 Comparison of Non-human Primate Versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction Stem Cell Reports. 02, 2018 | Pubmed ID: 29398480 Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery Annual Review of Pharmacology and Toxicology. 01, 2018 | Pubmed ID: 29029591 Generation of a KLF15 Homozygous Knockout Human Embryonic Stem Cell Line Using Paired CRISPR/Cas9n, and Human Cardiomyocytes Derivation Stem Cell Research. 08, 2017 | Pubmed ID: 28925362 Myocardial Tissue Engineering for Regenerative Applications Current Cardiology Reports. 09, 2017 | Pubmed ID: 28752277 Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair Circulation. May, 2017 | Pubmed ID: 28167635 Translating Myocardial Remuscularization Circulation Research. 01, 2017 | Pubmed ID: 28104769 Strip and Dress the Human Heart Circulation Research. Jan, 2016 | Pubmed ID: 26837739 Mechanical Stimulation in the Engineering of Heart Muscle Advanced Drug Delivery Reviews. Jan, 2016 | Pubmed ID: 26362920 New Biologics for the Modulation of Post-Infarct Remodeling: Matricryptins Journal of the American College of Cardiology. Sep, 2015 | Pubmed ID: 26383725 Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model Circulation Research. Sep, 2015 | Pubmed ID: 26291556 Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator Circulation Research. Aug, 2015 | Pubmed ID: 26078285 Physiologic Force-frequency Response in Engineered Heart Muscle by Electromechanical Stimulation Biomaterials. Aug, 2015 | Pubmed ID: 25985155 [Individualized Stem Cell Therapy] Herz. Mar, 2014 | Pubmed ID: 24589843 Modeling Myocardial Growth and Hypertrophy in Engineered Heart Muscle Trends in Cardiovascular Medicine. Jan, 2014 | Pubmed ID: 23953977 Signatures Communes De Micro-ARN Dans Le Remodelage Cardiaque Hypertrophique Et Atrophique Induite Par Des Changements De Charge Hémodynamique PloS One. 2010 | Pubmed ID: 21151612 Cardiac Tissue Engineering: Implications for Pediatric Heart Surgery Pediatric Cardiology. Jul, 2009 | Pubmed ID: 19319461 Tissu conjonctif humain dérivé de fibroblastes pour les applications de dépistage Gabriela L. Santos1,2, Tim Meyer1,2, Malte Tiburcy1,2, Alisa DeGrave1,2, Wolfram-Hubertus Zimmermann1,2,3,4,5, Susanne Lutz1,2 1Institute of Pharmacology and Toxicology, University Medical Center Goettingen, 2DZHK (German Center for Cardiovascular Research) partner site, Goettingen, 3Cluster of Excellence “Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells” (MBExC), University of Goettingen, 4Center for Neurodegenerative Diseases (DZNE), 5Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) JoVE 62700 Bioengineering
Tissu conjonctif humain dérivé de fibroblastes pour les applications de dépistage Gabriela L. Santos1,2, Tim Meyer1,2, Malte Tiburcy1,2, Alisa DeGrave1,2, Wolfram-Hubertus Zimmermann1,2,3,4,5, Susanne Lutz1,2 1Institute of Pharmacology and Toxicology, University Medical Center Goettingen, 2DZHK (German Center for Cardiovascular Research) partner site, Goettingen, 3Cluster of Excellence “Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells” (MBExC), University of Goettingen, 4Center for Neurodegenerative Diseases (DZNE), 5Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) JoVE 62700 Bioengineering