Xiao-Yu Tian School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences Chinese University of Hong Kong Biography Publications Institution JoVE Articles Xiao-Yu Tian has not added a biography. If you are Xiao-Yu Tian and would like to personalize this page please email our Author Liaison for assistance. Publications Uncoupling Protein 2 in Cardiovascular Health and Disease Frontiers in Physiology. 2018 | Pubmed ID: 30116205 Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes Cell Reports. Aug, 2018 | Pubmed ID: 30089270 Recent Advances in Managing Atherosclerosis Via Nanomedicine Small (Weinheim an Der Bergstrasse, Germany). Jan, 2018 | Pubmed ID: 29239134 Inhibition of MiR-92a Suppresses Oxidative Stress and Improves Endothelial Function by Upregulating Heme Oxygenase-1 in Db/db Mice Antioxidants & Redox Signaling. 02, 2018 | Pubmed ID: 28683566 Comprehensive Analysis of Acylcarnitine Species in Db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes Analytical Chemistry. Oct, 2017 | Pubmed ID: 28859482 Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells Stem Cell Reports. 03, 2017 | Pubmed ID: 28262545 Myeloid Deletion Increases Monocyte Recruitment and Worsens Atherosclerosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27927724 PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Diabetes. 02, 2017 | Pubmed ID: 27856609 Integrin-YAP/TAZ-JNK Cascade Mediates Atheroprotective Effect of Unidirectional Shear Flow Nature. Dec, 2016 | Pubmed ID: 27926730 Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis Frontiers in Physiology. 2016 | Pubmed ID: 27536244 Melamine Impairs Renal and Vascular Function in Rats Scientific Reports. 06, 2016 | Pubmed ID: 27324576 E-selectin-targeting Delivery of MicroRNAs by Microparticles Ameliorates Endothelial Inflammation and Atherosclerosis Scientific Reports. Mar, 2016 | Pubmed ID: 26956647 Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016 | Pubmed ID: 26769046 Chronic Black Tea Extract Consumption Improves Endothelial Function in Ovariectomized Rats European Journal of Nutrition. Aug, 2016 | Pubmed ID: 26276555 A Revisit on the Renin-angiotensin System in Cardiovascular Biology Trends in Cardiovascular Medicine. Apr, 2016 | Pubmed ID: 26212445 Black Tea Protects Against Hypertension-associated Endothelial Dysfunction Through Alleviation of Endoplasmic Reticulum Stress Scientific Reports. May, 2015 | Pubmed ID: 25976123 Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes Antioxidants & Redox Signaling. Oct, 2015 | Pubmed ID: 25867182 Unconjugated Bilirubin Mediates Heme Oxygenase-1-induced Vascular Benefits in Diabetic Mice Diabetes. May, 2015 | Pubmed ID: 25475440 The Peroxisome Proliferator-activated Receptors in Cardiovascular Diseases: Experimental Benefits and Clinical Challenges British Journal of Pharmacology. Dec, 2015 | Pubmed ID: 25438608 Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension Via Differential Regulation of ET-1 Receptors PPAR Research. 2014 | Pubmed ID: 24701204 Metformin Protects Endothelial Function in Diet-induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5' Adenosine Monophosphate-activated Protein Kinase-peroxisome Proliferator-activated Receptor δ Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2014 | Pubmed ID: 24482374 Uncoupling Protein-2 Mediates DPP-4 Inhibitor-induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress Antioxidants & Redox Signaling. Oct, 2014 | Pubmed ID: 24328731 Inhibition of Bone Morphogenic Protein 4 Restores Endothelial Function in Db/db Diabetic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24202302 Pleiotropic Effects of Peroxisome Proliferator-activated Receptor γ and δ in Vascular Diseases Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 24107399 Boldine Improves Endothelial Function in Diabetic Db/db Mice Through Inhibition of Angiotensin II-mediated BMP4-oxidative Stress Cascade British Journal of Pharmacology. Nov, 2013 | Pubmed ID: 23992296 Menthol Relaxes Rat Aortae, Mesenteric and Coronary Arteries by Inhibiting Calcium Influx European Journal of Pharmacology. Feb, 2013 | Pubmed ID: 23380688 Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function Through Increasing Endothelial Nitric Oxide Synthase Activity PloS One. 2012 | Pubmed ID: 23284736 PPARδ 活性化糖尿病マウスにおける内皮機能を保護します。 Diabetes. Dec, 2012 | Pubmed ID: 22933110 ジペプチジルペプチダーゼ ペプチダーゼ 4 阻害剤シタグリプチン グルカゴン様ペプチド 1 依存型メカニズムを通じて高血圧症における血管内皮機能を保護します。 Hypertension. Sep, 2012 | Pubmed ID: 22868389 慢性のクランベリー ジュースの消費量はコレステロールのプロフィールを復元し、卵巣摘出ラットにおける内皮機能を改善します。 European Journal of Nutrition. Jul, 2012 | Pubmed ID: 22836513 Capsaicinoids 血漿コレステロールを下げるし、ハムスターにおける内皮機能を改善します。 European Journal of Nutrition. Mar, 2012 | Pubmed ID: 22466858 NaHS in Vitro L 型電圧感受性カルシウム チャネルの抑制を介してラット大脳動脈を弛緩させます。 Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22133671 骨形成タンパク質-4 JNK 経路と酸化ストレス依存 P38MAPK を介して血管内皮細胞のアポトーシスを誘導します。 Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22064324 ラロキシフェン コレステロール食飼育卵巣摘出ハムスターの加圧隔冠状動脈の血管の反応性が向上します。 Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22005391 酸化ストレス依存シクロオキシゲナーゼ-2由来のプロスタグランジンF(2α)は、腎血管性高血圧ラットにおける血管内皮機能を損なう Antioxidants & Redox Signaling. Feb, 2012 | Pubmed ID: 21951274 内皮型一酸化窒素合成酵素のエンハンサーは、酸化ストレスを軽減し、db/db マウスにおける内皮機能を復元します。 Cardiovascular Research. Nov, 2011 | Pubmed ID: 21875904 アディポネクチンは糖尿病マウスにおける内皮機能の改善の Ppar γ を介する必要があります。 Cell Metabolism. Jul, 2011 | Pubmed ID: 21723508 リポタンパク質プロファイルとハムスターの血管機能に及ぼす植物ステロールとその酸化物の高コレステロール食を供給しました。 Atherosclerosis. Nov, 2011 | Pubmed ID: 21719014 レニン-アンジオテンシン系阻害内皮機能不全とエストロゲン欠乏ラットにおける酸化ストレスを反転します。 PloS One. 2011 | Pubmed ID: 21479266 AVE3085、内皮一酸化窒素シンターゼのエンハンサーは、血管内皮機能を復元し、発症高血圧ラットの血圧を低減します。 British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21385179 テルミ Ppar γ 依存式と内皮一酸化窒素合成酵素の活性化を介して血管収縮を抑制します。 Cardiovascular Research. Apr, 2011 | Pubmed ID: 21156825 プロスタグランジンのシクロオキシゲナーゼ-1 と-2 内皮依存性収縮でのアクションの欠かせない役割で。 Advances in Pharmacology (San Diego, Calif.). 2010 | Pubmed ID: 21081215 骨形成タンパク質-4 損なう酸化ストレス依存シクロオキシゲナーゼ 2 のアップレギュレーションを介して血管内皮機能: 高血圧への影響。 Circulation Research. Oct, 2010 | Pubmed ID: 20724703 4 アミノピリジン感受性 K + チャネル NaHS 誘起膜過分極およびラット冠動脈における緩和に貢献しています。 Vascular Pharmacology. Sep-Oct, 2010 | Pubmed ID: 20430111 内皮機能不全: 糖尿病と高血圧の共通の帰結。 Journal of Cardiovascular Pharmacology. Apr, 2010 | Pubmed ID: 20422734 アンジオテンシン II タイプ 1 受容体に依存する酸化ストレスは 2 型糖尿病マウスにおける内皮機能不全を仲介します。 Antioxidants & Redox Signaling. Sep, 2010 | Pubmed ID: 20136508 誘導多能性幹細胞由来肝細胞を用いた家族性高コレステロール血症ひと肝臓キメラマウス モデル Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology
誘導多能性幹細胞由来肝細胞を用いた家族性高コレステロール血症ひと肝臓キメラマウス モデル Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology