Xiao-Yu Tian School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences Chinese University of Hong Kong Biography Publications Institution JoVE Articles Xiao-Yu Tian has not added a biography. If you are Xiao-Yu Tian and would like to personalize this page please email our Author Liaison for assistance. Publications Uncoupling Protein 2 in Cardiovascular Health and Disease Frontiers in Physiology. 2018 | Pubmed ID: 30116205 Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes Cell Reports. Aug, 2018 | Pubmed ID: 30089270 Recent Advances in Managing Atherosclerosis Via Nanomedicine Small (Weinheim an Der Bergstrasse, Germany). Jan, 2018 | Pubmed ID: 29239134 Inhibition of MiR-92a Suppresses Oxidative Stress and Improves Endothelial Function by Upregulating Heme Oxygenase-1 in Db/db Mice Antioxidants & Redox Signaling. 02, 2018 | Pubmed ID: 28683566 Comprehensive Analysis of Acylcarnitine Species in Db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes Analytical Chemistry. Oct, 2017 | Pubmed ID: 28859482 Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells Stem Cell Reports. 03, 2017 | Pubmed ID: 28262545 Myeloid Deletion Increases Monocyte Recruitment and Worsens Atherosclerosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27927724 PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Diabetes. 02, 2017 | Pubmed ID: 27856609 Integrin-YAP/TAZ-JNK Cascade Mediates Atheroprotective Effect of Unidirectional Shear Flow Nature. Dec, 2016 | Pubmed ID: 27926730 Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis Frontiers in Physiology. 2016 | Pubmed ID: 27536244 Melamine Impairs Renal and Vascular Function in Rats Scientific Reports. 06, 2016 | Pubmed ID: 27324576 E-selectin-targeting Delivery of MicroRNAs by Microparticles Ameliorates Endothelial Inflammation and Atherosclerosis Scientific Reports. Mar, 2016 | Pubmed ID: 26956647 Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016 | Pubmed ID: 26769046 Chronic Black Tea Extract Consumption Improves Endothelial Function in Ovariectomized Rats European Journal of Nutrition. Aug, 2016 | Pubmed ID: 26276555 A Revisit on the Renin-angiotensin System in Cardiovascular Biology Trends in Cardiovascular Medicine. Apr, 2016 | Pubmed ID: 26212445 Black Tea Protects Against Hypertension-associated Endothelial Dysfunction Through Alleviation of Endoplasmic Reticulum Stress Scientific Reports. May, 2015 | Pubmed ID: 25976123 Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes Antioxidants & Redox Signaling. Oct, 2015 | Pubmed ID: 25867182 Unconjugated Bilirubin Mediates Heme Oxygenase-1-induced Vascular Benefits in Diabetic Mice Diabetes. May, 2015 | Pubmed ID: 25475440 The Peroxisome Proliferator-activated Receptors in Cardiovascular Diseases: Experimental Benefits and Clinical Challenges British Journal of Pharmacology. Dec, 2015 | Pubmed ID: 25438608 Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension Via Differential Regulation of ET-1 Receptors PPAR Research. 2014 | Pubmed ID: 24701204 Metformin Protects Endothelial Function in Diet-induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5' Adenosine Monophosphate-activated Protein Kinase-peroxisome Proliferator-activated Receptor δ Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2014 | Pubmed ID: 24482374 Uncoupling Protein-2 Mediates DPP-4 Inhibitor-induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress Antioxidants & Redox Signaling. Oct, 2014 | Pubmed ID: 24328731 Inhibition of Bone Morphogenic Protein 4 Restores Endothelial Function in Db/db Diabetic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24202302 Pleiotropic Effects of Peroxisome Proliferator-activated Receptor γ and δ in Vascular Diseases Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 24107399 Boldine Improves Endothelial Function in Diabetic Db/db Mice Through Inhibition of Angiotensin II-mediated BMP4-oxidative Stress Cascade British Journal of Pharmacology. Nov, 2013 | Pubmed ID: 23992296 Menthol Relaxes Rat Aortae, Mesenteric and Coronary Arteries by Inhibiting Calcium Influx European Journal of Pharmacology. Feb, 2013 | Pubmed ID: 23380688 Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function Through Increasing Endothelial Nitric Oxide Synthase Activity PloS One. 2012 | Pubmed ID: 23284736 Activación De PPARδ Protege La Función Endotelial En Ratones Diabéticos Diabetes. Dec, 2012 | Pubmed ID: 22933110 Sitagliptina De Inhibidor De La Dipeptidil Peptidasa 4 Protege La Función Endotelial En La Hipertensión a Través De Un Mecanismo De Péptido Similar Al Glucagón 1-dependiente Hypertension. Sep, 2012 | Pubmed ID: 22868389 Consumo De Jugo De Arándano Rojo Crónica Restaura Perfiles De Colesterol Y Mejora La Función Endotelial En Ratas Ovariectomizadas European Journal of Nutrition. Jul, 2012 | Pubmed ID: 22836513 Capsaicinoides Bajar Colesterol Del Plasma Y Mejoran La Función Endotelial En Los Hámsters European Journal of Nutrition. Mar, 2012 | Pubmed ID: 22466858 NaHS Relaja Arteria Cerebral De La Rata in Vitro Mediante La Inhibición De Los Canales De Tipo L Sensibles Al Voltaje Ca Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22133671 Proteína Morfogénica Hueso-4 Induce La Apoptosis De Las Células Endoteliales a Través De P38MAPK De Dependiente De Estrés Oxidativo Y Vía JNK Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22064324 Raloxifeno Mejora La Reactividad Vascular En Coronarias Septales Presurizados De Ovariectomizadas Hámsteres Alimentados Con Dieta De Colesterol Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22005391 Estrés Oxidativo Dependiente De La Ciclooxigenasa-2-derivado De La Prostaglandina F (2α) Altera La Función Endotelial En Ratas Hipertensas Renovasculares Antioxidants & Redox Signaling. Feb, 2012 | Pubmed ID: 21951274 Endotelial De óxido Nítrico Sintasa Enhancer Reduce El Estrés Oxidativo Y Restaura La Función Endotelial En Ratones Db/db Cardiovascular Research. Nov, 2011 | Pubmed ID: 21875904 Adiponectina Se Requiere Para PPARy Mediada Por La Mejora De La Función Endotelial En Ratones Diabéticos Cell Metabolism. Jul, 2011 | Pubmed ID: 21723508 Efecto De Fitosteroles Y Sus Productos De Oxidación En Los Perfiles De La Lipoproteína Y Función Vascular En Hámster Alimentados Con Una Dieta De Colesterol Alto Atherosclerosis. Nov, 2011 | Pubmed ID: 21719014 Inhibición Del Sistema Renina-angiotensina Revierte La Disfunción Endotelial Y El Estrés Oxidativo En Ratas Deficientes De Estrógeno PloS One. 2011 | Pubmed ID: 21479266 AVE3085, Un Potenciador De La óxido Nítrico Sintasa Endotelial, Restaura La Función Endotelial Y Reduce La Presión Arterial En Ratas De Espontáneamente Hipertensas British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21385179 Telmisartán Inhibe La Vasoconstricción Vía Expresión De PPARy-dependiente Y La Activación De La óxido Nítrico Sintasa Endotelial Cardiovascular Research. Apr, 2011 | Pubmed ID: 21156825 Prostaglandinas En Papeles Indispensable Acción De La Ciclooxigenasa-1 Y -2 En Contracciones Dependiente Del Endotelio Advances in Pharmacology (San Diego, Calif.). 2010 | Pubmed ID: 21081215 Proteína Morfogénica Hueso-4 Deteriora La Función Endotelial Mediante Upregulation De Ciclooxigenasa-2 Dependiente De Estrés Oxidativo: Implicaciones Para La Hipertensión Circulation Research. Oct, 2010 | Pubmed ID: 20724703 Canales 4-aminopiridina Sensible K + Contribuye a La Hiperpolarización De La Membrana Inducida Por NaHS Y Relajación En La Arteria Coronaria De Rata Vascular Pharmacology. Sep-Oct, 2010 | Pubmed ID: 20430111 Disfunción Endotelial: La Consecuencia Común En La Diabetes Y La Hipertensión Journal of Cardiovascular Pharmacology. Apr, 2010 | Pubmed ID: 20422734 Estrés Oxidativo De Angiotensina II Tipo 1 Del Receptor Dependiente Media Disfunción Endotelial En Ratones Diabéticos Tipo 2 Antioxidants & Redox Signaling. Sep, 2010 | Pubmed ID: 20136508 Un modelo de ratón quimérico hígado humano de hipercolesterolemia familiar con hepatocitos derivados de células madre pluripotentes inducidas Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology
Un modelo de ratón quimérico hígado humano de hipercolesterolemia familiar con hepatocitos derivados de células madre pluripotentes inducidas Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology