Xiaoke Yin King's British Heart Foundation Centre King's College London Biography Publications Institution JoVE Articles Xiaoke Yin has not added a biography. If you are Xiaoke Yin and would like to personalize this page please email our Author Liaison for assistance. Publications Extracellular Matrix Proteomics Identifies Molecular Signature of Symptomatic Carotid Plaques The Journal of Clinical Investigation. Apr, 2017 | Pubmed ID: 28319050 Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III Journal of the American College of Cardiology. Feb, 2017 | Pubmed ID: 28209220 Premature Senescence of Endothelial Cells Upon Chronic Exposure to TNFα Can Be Prevented by N-acetyl Cysteine and Plumericin Scientific Reports. Jan, 2017 | Pubmed ID: 28045034 Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes Diabetes. Feb, 2017 | Pubmed ID: 27899485 Systems Biology-opportunities and Challenges: the Application of Proteomics to Study the Cardiovascular Extracellular Matrix Cardiovascular Research. Dec, 2016 | Pubmed ID: 27635058 Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation Circulation. Sep, 2016 | Pubmed ID: 27559042 Identification of Cyclins A1, E1 and Vimentin As Downstream Targets of Heme Oxygenase-1 in Vascular Endothelial Growth Factor-mediated Angiogenesis Scientific Reports. Jul, 2016 | Pubmed ID: 27388959 Proteomic and Metabolomic Changes Driven by Elevating Myocardial Creatine Suggest Novel Metabolic Feedback Mechanisms Amino Acids. Aug, 2016 | Pubmed ID: 27143170 Chronic MiR-29 Antagonism Promotes Favorable Plaque Remodeling in Atherosclerotic Mice EMBO Molecular Medicine. 06, 2016 | Pubmed ID: 27137489 Extracellular Matrix Remodelling in Response to Venous Hypertension: Proteomics of Human Varicose Veins Cardiovascular Research. 06, 2016 | Pubmed ID: 27068509 Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2016 | Pubmed ID: 27034473 "Young at Heart": Regenerative Potential Linked to Immature Cardiac Phenotypes Journal of Molecular and Cellular Cardiology. Mar, 2016 | Pubmed ID: 26827899 Association of MicroRNAs and YRNAs With Platelet Function Circulation Research. Feb, 2016 | Pubmed ID: 26646931 Angiogenic MicroRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes Diabetes. Jan, 2016 | Pubmed ID: 26395742 XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2015 | Pubmed ID: 26315405 Cardiac-targeted NADPH Oxidase 4 in the Adaptive Cardiac Remodelling of the Murine Heart Lancet (London, England). Feb, 2015 | Pubmed ID: 26312895 ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1 Circulation. Feb, 2015 | Pubmed ID: 25712208 Vascular Smooth Muscle Cell Calcification is Mediated by Regulated Exosome Secretion Circulation Research. Apr, 2015 | Pubmed ID: 25711438 Role of MiR-195 in Aortic Aneurysmal Disease Circulation Research. Oct, 2014 | Pubmed ID: 25201911 Long-term Therapeutic Silencing of MiR-33 Increases Circulating Triglyceride Levels and Hepatic Lipid Accumulation in Mice EMBO Molecular Medicine. Jul, 2014 | Pubmed ID: 25038053 Redox State of Pentraxin 3 As a Novel Biomarker for Resolution of Inflammation and Survival in Sepsis Molecular & Cellular Proteomics : MCP. Oct, 2014 | Pubmed ID: 24958171 Cardiac Fibroblast-derived MicroRNA Passenger Strand-enriched Exosomes Mediate Cardiomyocyte Hypertrophy The Journal of Clinical Investigation. May, 2014 | Pubmed ID: 24743145 Over-expression of HSP47 Augments Mouse Embryonic Stem Cell Smooth Muscle Differentiation and Chemotaxis PloS One. 2014 | Pubmed ID: 24454956 Matrix Metalloproteinase-8 Promotes Vascular Smooth Muscle Cell Proliferation and Neointima Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24158518 Gene Network and Proteomic Analyses of Cardiac Responses to Pathological and Physiological Stress Circulation. Cardiovascular Genetics. Dec, 2013 | Pubmed ID: 24214729 Histone Deacetylase 3 Unconventional Splicing Mediates Endothelial-to-mesenchymal Transition Through Transforming Growth Factor β2 The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24045946 The Hypoxia-inducible MicroRNA Cluster MiR-199a∼214 Targets Myocardial PPARδ and Impairs Mitochondrial Fatty Acid Oxidation Cell Metabolism. Sep, 2013 | Pubmed ID: 24011070 Extracellular Matrix Secretion by Cardiac Fibroblasts: Role of MicroRNA-29b and MicroRNA-30c Circulation Research. Oct, 2013 | Pubmed ID: 24006456 Gestational Diabetes Mellitus Impairs Nrf2-mediated Adaptive Antioxidant Defenses and Redox Signaling in Fetal Endothelial Cells in Utero Diabetes. Dec, 2013 | Pubmed ID: 23974919 Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure Circulation. Sep, 2013 | Pubmed ID: 23956210 Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties Molecular & Cellular Proteomics : MCP. Aug, 2013 | Pubmed ID: 23660474 A Sequential Extraction Methodology for Cardiac Extracellular Matrix Prior to Proteomics Analysis Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23606260 Glycoproteomic Analysis of the Secretome of Human Endothelial Cells Molecular & Cellular Proteomics : MCP. Apr, 2013 | Pubmed ID: 23345538 Effects of Perhexiline-induced Fuel Switch on the Cardiac Proteome and Metabolome Journal of Molecular and Cellular Cardiology. Feb, 2013 | Pubmed ID: 23277191 Cytochrome P4502S1: a Novel Monocyte/macrophage Fatty Acid Epoxygenase in Human Atherosclerotic Plaques Basic Research in Cardiology. Jan, 2013 | Pubmed ID: 23224081 Proteomics: from Single Molecules to Biological Pathways Cardiovascular Research. Mar, 2013 | Pubmed ID: 23180722 Functional Role of Matrix Metalloproteinase-8 in Stem/progenitor Cell Migration and Their Recruitment into Atherosclerotic Lesions Circulation Research. Jan, 2013 | Pubmed ID: 23071158 Calpain Inhibition Stabilizes the Platelet Proteome and Reactivity in Diabetes Blood. Jul, 2012 | Pubmed ID: 22665935 Atheroprotective Communication Between Endothelial Cells and Smooth Muscle Cells Through MiRNAs Nature Cell Biology. Feb, 2012 | Pubmed ID: 22327366 Method for Protein Subfractionation of Cardiovascular Tissues Before DIGE Analysis Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22311768 Proteomics Analysis of Cardiac Extracellular Matrix Remodeling in a Porcine Model of Ischemia/reperfusion Injury Circulation. Feb, 2012 | Pubmed ID: 22261194 Diferenciación Terminal, Avanzada Maduración Organotypic Y Modelado De Crecimiento Hipertrófico En Ingeniería Tejido Cardíaco Circulation Research. Oct, 2011 | Pubmed ID: 21921264 Substrate Modifications Precede the Development of Atrial Fibrillation After Cardiac Surgery: a Proteomic Study The Annals of Thoracic Surgery. Jul, 2011 | Pubmed ID: 21718835 Chromobox Protein Homolog 3 is Essential for Stem Cell Differentiation to Smooth Muscles in Vitro and in Embryonic Arteriogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2011 | Pubmed ID: 21659642 Adaptation to HIF-1 Deficiency by Upregulation of the AMP/ATP Ratio and Phosphofructokinase Activation in Hepatomas BMC Cancer. May, 2011 | Pubmed ID: 21612605 Extracellular Matrix Composition and Remodeling in Human Abdominal Aortic Aneurysms: a Proteomics Approach Molecular & Cellular Proteomics : MCP. Aug, 2011 | Pubmed ID: 21593211 Metabolic Homeostasis is Maintained in Myocardial Hibernation by Adaptive Changes in the Transcriptome and Proteome Journal of Molecular and Cellular Cardiology. Jun, 2011 | Pubmed ID: 21354174 Proteomic Characterization of Human Early Pro-angiogenic Cells Journal of Molecular and Cellular Cardiology. Feb, 2011 | Pubmed ID: 21147123 Proteomics Characterization of Extracellular Space Components in the Human Aorta Molecular & Cellular Proteomics : MCP. Sep, 2010 | Pubmed ID: 20551380 Short Communication: Asymmetric Dimethylarginine Impairs Angiogenic Progenitor Cell Function in Patients with Coronary Artery Disease Through a MicroRNA-21-dependent Mechanism Circulation Research. Jul, 2010 | Pubmed ID: 20489163 Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of Beta-catenin Circulation Research. Apr, 2010 | Pubmed ID: 20224040 Proteomics Analysis of the Cardiac Myofilament Subproteome Reveals Dynamic Alterations in Phosphatase Subunit Distribution Molecular & Cellular Proteomics : MCP. Mar, 2010 | Pubmed ID: 20037178 Proteomics, Metabolomics, and Immunomics on Microparticles Derived from Human Atherosclerotic Plaques Circulation. Cardiovascular Genetics. Aug, 2009 | Pubmed ID: 20031610 Proteomic Analysis of the Secretome of Human Umbilical Vein Endothelial Cells Using a Combination of Free-flow Electrophoresis and Nanoflow LC-MS/MS Proteomics. Nov, 2009 | Pubmed ID: 19810032 Identification of Cardiac Myosin-binding Protein C As a Candidate Biomarker of Myocardial Infarction by Proteomics Analysis Molecular & Cellular Proteomics : MCP. Dec, 2009 | Pubmed ID: 19721077 Proteomics Identifies Thymidine Phosphorylase As a Key Regulator of the Angiogenic Potential of Colony-forming Units and Endothelial Progenitor Cell Cultures Circulation Research. Jan, 2009 | Pubmed ID: 19023133 Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived from the Arterial Media and Adventitial Progenitors of Apolipoprotein E-deficient Mice Circulation Research. May, 2008 | Pubmed ID: 18388323 Combined Metabolomic and Proteomic Analysis of Human Atrial Fibrillation Journal of the American College of Cardiology. Feb, 2008 | Pubmed ID: 18237690 Integrated Membrane Protein Analysis of Mature and Embryonic Stem Cell-derived Smooth Muscle Cells Using a Novel Combination of CyDye/biotin Labeling Molecular & Cellular Proteomics : MCP. Oct, 2007 | Pubmed ID: 17627936 Protein Kinase D Selectively Targets Cardiac Troponin I and Regulates Myofilament Ca2+ Sensitivity in Ventricular Myocytes Circulation Research. Mar, 2007 | Pubmed ID: 17322173 Proteomic Analysis Reveals Higher Demand for Antioxidant Protection in Embryonic Stem Cell-derived Smooth Muscle Cells Proteomics. Dec, 2006 | Pubmed ID: 17163435 Proteomic Dataset of Mouse Aortic Smooth Muscle Cells Proteomics. Nov, 2005 | Pubmed ID: 16240290 Proteomic Dataset of Sca-1+ Progenitor Cells Proteomics. Nov, 2005 | Pubmed ID: 16240289 Proteomic and Metabolomic Analyses of Atherosclerotic Vessels from Apolipoprotein E-deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2005 | Pubmed ID: 16123314 Vascular Proteomics: Linking Proteomic and Metabolomic Changes Proteomics. Dec, 2004 | Pubmed ID: 15540213 Glycoproteomics de la matriz extracelular: Un método para el análisis glucopéptidos Intacto El uso de la espectrometría de masas Javier Barallobre-Barreiro1, Ferheen Baig1, Marika Fava1, Xiaoke Yin1, Manuel Mayr1 1King's British Heart Foundation Centre, King's College London JoVE 55674 Biochemistry
Glycoproteomics de la matriz extracelular: Un método para el análisis glucopéptidos Intacto El uso de la espectrometría de masas Javier Barallobre-Barreiro1, Ferheen Baig1, Marika Fava1, Xiaoke Yin1, Manuel Mayr1 1King's British Heart Foundation Centre, King's College London JoVE 55674 Biochemistry