Xiaolu Yang Department of Cancer Biology University of Pennsylvania Perelman School of Medicine Biography Publications Institution JoVE Articles Xiaolu Yang has not added a biography. If you are Xiaolu Yang and would like to personalize this page please email our Author Liaison for assistance. Publications Two SNAP-25 Genetic Variants in the Binding Site of Multiple MicroRNAs and Susceptibility of ADHD: A Meta-analysis Journal of Psychiatric Research. Jun, 2016 | Pubmed ID: 27380186 Isolation and Evaluation of Endophytic Streptomyces Endus OsiSh-2 with Potential Application for Biocontrol of Rice Blast Disease Journal of the Science of Food and Agriculture. Jun, 2016 | Pubmed ID: 27293085 Molecular Basis and Consequences of the Cytochrome C-tRNA Interaction The Journal of Biological Chemistry. May, 2016 | Pubmed ID: 26961879 PAPep, a Small Peptide Derived from Human Pancreatitis-associated Protein, Attenuates Corneal Inflammation in Vivo and in Vitro Through the IKKα/β/IκBα/NF-κB Signaling Pathway Pharmacological Research. Dec, 2015 | Pubmed ID: 26388492 Peptidyl-prolyl Isomerization Targets Rice Aux/IAAs for Proteasomal Degradation During Auxin Signalling Nature Communications. 2015 | Pubmed ID: 26096057 A Cellular System That Degrades Misfolded Proteins and Protects Against Neurodegeneration Molecular Cell. Jul, 2014 | Pubmed ID: 24882209 Stabilized Human TRIM5α Protects Human T Cells from HIV-1 Infection Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2014 | Pubmed ID: 24662946 MicroRNA-93 Inhibits Inflammatory Cytokine Production in LPS-stimulated Murine Macrophages by Targeting IRAK4 FEBS Letters. May, 2014 | Pubmed ID: 24642374 Distinctive Effects of the Cellular Inhibitor of Apoptosis Protein C-IAP2 Through Stabilization by XIAP in Glioblastoma Multiforme Cells Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 24552816 Olive Leaf Extract Inhibits Lead Poisoning-induced Brain Injury Neural Regeneration Research. Aug, 2013 | Pubmed ID: 25206510 P53 and Regulation of Tumor Metabolism Journal of Carcinogenesis. 2013 | Pubmed ID: 24379735 A Critical Role of Glucose-6-phosphate Dehydrogenase in TAp73-mediated Cell Proliferation Cell Cycle (Georgetown, Tex.). Dec, 2013 | Pubmed ID: 24270845 TAp73 Enhances the Pentose Phosphate Pathway and Supports Cell Proliferation Nature Cell Biology. Aug, 2013 | Pubmed ID: 23811687 Auto-ubiquitination of Mdm2 Enhances Its Substrate Ubiquitin Ligase Activity The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23671280 Phosphorylation of Daxx by ATM Contributes to DNA Damage-induced P53 Activation PloS One. 2013 | Pubmed ID: 23405218 Effects of a Thrombomodulin-derived Peptide on Monocyte Adhesion and Intercellular Adhesion Molecule-1 Expression in Lipopolysaccharide-induced Endothelial Cells Molecular Vision. 2013 | Pubmed ID: 23401649 Regulation of Cell Death by Transfer RNA Antioxidants & Redox Signaling. Aug, 2013 | Pubmed ID: 23350625 Reciprocal Regulation of P53 and Malic Enzymes Modulates Metabolism and Senescence Nature. Jan, 2013 | Pubmed ID: 23334421 Gd Complexes of Diethylenetriaminepentaacetic Acid Conjugates of Low-molecular-weight Chitosan Oligosaccharide As a New Liver-specific MRI Contrast Agent Magnetic Resonance Imaging. May, 2013 | Pubmed ID: 23102519 Dissecting the Complex Regulation of Mad4 in Glioblastoma Multiforme Cells Cancer Biology & Therapy. Nov, 2012 | Pubmed ID: 22895069 A20 Ubiquitin Ligase-mediated Polyubiquitination of RIP1 Inhibits Caspase-8 Cleavage and TRAIL-induced Apoptosis in Glioblastoma Cancer Discovery. Feb, 2012 | Pubmed ID: 22585859 Chemical Composition of Volatile Oil from Artemisia Ordosica and Its Allelopathic Effects on Desert Soil Microalgae, Palmellococcus Miniatus Plant Physiology and Biochemistry : PPB / Société Française De Physiologie Végétale. Feb, 2012 | Pubmed ID: 22153252 A Novel Peptide Derived from Human Pancreatitis-associated Protein Inhibits Inflammation in Vivo and in Vitro and Blocks NF-kappa B Signaling Pathway PloS One. 2011 | Pubmed ID: 22195011 Crystal Structure of the Mucosa-associated Lymphoid Tissue Lymphoma Translocation 1 (MALT1) Paracaspase Region Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22158899 [Mitochondrial Dysfunction Induced by Excessive ROS/RNS-metabolic Cardiovascular Disease and Traditional Chinese Medicines Intervention] Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. Sep, 2011 | Pubmed ID: 22121816 Effects of a Novel Peptide Derived from Human Thrombomodulin on Endotoxin-induced Uveitis in Vitro and in Vivo FEBS Letters. Nov, 2011 | Pubmed ID: 22001200 The USP19 Deubiquitinase Regulates the Stability of C-IAP1 and C-IAP2 The Journal of Biological Chemistry. Oct, 2011 | Pubmed ID: 21849505 Siva1 Suppresses Epithelial-mesenchymal Transition and Metastasis of Tumor Cells by Inhibiting Stathmin and Stabilizing Microtubules Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21768358 P53 Regulates Biosynthesis Through Direct Inactivation of Glucose-6-phosphate Dehydrogenase Nature Cell Biology. Mar, 2011 | Pubmed ID: 21336310 [Study on Effect of Total Saponins from Semen Nigellae on Inflammatory Mediators and ERK/MAPK Pathway in Stimulated Macrophage] Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. Oct, 2010 | Pubmed ID: 21174772 Apoptotic Regulation and TRNA Protein & Cell. Sep, 2010 | Pubmed ID: 21113408 TRNA and Cytochrome C in Cell Death and Beyond Cell Cycle (Georgetown, Tex.). Aug, 2010 | Pubmed ID: 20676046 TRNA Binds to Cytochrome C and Inhibits Caspase Activation Molecular Cell. Mar, 2010 | Pubmed ID: 20227371 Daxx is Reciprocally Regulated by Mdm2 and Hausp Biochemical and Biophysical Research Communications. Mar, 2010 | Pubmed ID: 20153724 Distinct MHC Gene Expression Patterns During Progression of Melanoma Genes, Chromosomes & Cancer. Feb, 2010 | Pubmed ID: 19862823 Inhibition of JAK2/STAT3-mediated VEGF Upregulation Under High Glucose Conditions by PEDF Through a Mitochondrial ROS Pathway in Vitro Investigative Ophthalmology & Visual Science. Jan, 2010 | Pubmed ID: 19696171 Noncanonical NF-kappaB Activation Requires Coordinated Assembly of a Regulatory Complex of the Adaptors CIAP1, CIAP2, TRAF2 and TRAF3 and the Kinase NIK Nature Immunology. Dec, 2008 | Pubmed ID: 18997794 The Paracaspase MALT1 Controls Caspase-8 Activation During Lymphocyte Proliferation Molecular Cell. Aug, 2008 | Pubmed ID: 18691973 Ubiquitination Mediated by Inhibitor of Apoptosis Proteins Methods in Enzymology. 2008 | Pubmed ID: 18603125 TIPE2, a Negative Regulator of Innate and Adaptive Immunity That Maintains Immune Homeostasis Cell. May, 2008 | Pubmed ID: 18455983 Lys63-linked Polyubiquitin Chains: Linking More Than Just Ubiquitin Cancer Biology & Therapy. Oct, 2006 | Pubmed ID: 16969079 Critical Role for Daxx in Regulating Mdm2 Nature Cell Biology. Aug, 2006 | Pubmed ID: 16845383 A Novel Fusion of the MALT1 Gene and the Microtubule-associated Protein 4 (MAP4) Gene Occurs in Diffuse Large B-cell Lymphoma Genes, Chromosomes & Cancer. Sep, 2006 | Pubmed ID: 16804917 CIAP2 Inhibits Anigen Receptor Signaling by Targeting Bcl10 for Degredation Cell Cycle (Georgetown, Tex.). Jul, 2006 | Pubmed ID: 16775419 CIAP2 is a Ubiquitin Protein Ligase for BCL10 and is Dysregulated in Mucosa-associated Lymphoid Tissue Lymphomas The Journal of Clinical Investigation. Jan, 2006 | Pubmed ID: 16395405 Lymphocyte Life and Death: the Caspase-8 Connection Cancer Biology & Therapy. Jul, 2005 | Pubmed ID: 16082181 Association of Caspase-2 with the Promyelocytic Leukemia Protein Nuclear Bodies Cancer Biology & Therapy. Jun, 2005 | Pubmed ID: 15917662 The Death Domain-associated Protein Modulates Activity of the Transcription Co-factor Skip/NcoA62 FEBS Letters. May, 2005 | Pubmed ID: 15878163 Interdimer Processing and Linearity of Procaspase-3 Activation. A Unifying Mechanism for the Activation of Initiator and Effector Caspases The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15664982 A Novel Transcription Regulatory Complex Containing Death Domain-associated Protein and the ATR-X Syndrome Protein The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14990586 Interdimer Processing Mechanism of Procaspase-8 Activation The EMBO Journal. Aug, 2003 | Pubmed ID: 12912912 Oligomerization is a General Mechanism for the Activation of Apoptosis Initiator and Inflammatory Procaspases The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12637514 Activation of Procaspases by FK506 Binding Protein-mediated Oligomerization Science's STKE : Signal Transduction Knowledge Environment. Jan, 2003 | Pubmed ID: 12554853 DEDD and DEDD2 Associate with Caspase-8/10 and Signal Cell Death Oncogene. Jan, 2003 | Pubmed ID: 12527898 Cellular Inhibitor of Apoptosis 1 and 2 Are Ubiquitin Ligases for the Apoptosis Inducer Smac/DIABLO The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12525502 The FLIP Side of Cancer Cell Death Cancer Biology & Therapy. Jul-Aug, 2002 | Pubmed ID: 12432256 C-FLIP(L) is a Dual Function Regulator for Caspase-8 Activation and CD95-mediated Apoptosis The EMBO Journal. Jul, 2002 | Pubmed ID: 12110583 Assays for nedbrytning av misfoldede Proteiner i Cells Lili Guo1,2, Wil Prall1, Xiaolu Yang1 1Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, 2Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine Biology
Assays for nedbrytning av misfoldede Proteiner i Cells Lili Guo1,2, Wil Prall1, Xiaolu Yang1 1Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, 2Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine Biology