Yaohe Wang National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre, School of Basic Medical Sciences Zhengzhou University Biography Publications Institution JoVE Articles Yaohe Wang has not added a biography. If you are Yaohe Wang and would like to personalize this page please email our Author Liaison for assistance. Publications Re-designing Interleukin-12 to Enhance Its Safety and Potential As an Anti-tumor Immunotherapeutic Agent Nature Communications. Nov, 2017 | Pubmed ID: 29123084 Correction for Spurrell Et Al., "STAT1 Interaction with E3-14.7K in Monocytes Affects the Efficacy of Oncolytic Adenovirus" Journal of Virology. Oct, 2017 | Pubmed ID: 28956778 Oncolytic Viruses-Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer Frontiers in Oncology. 2017 | Pubmed ID: 28944214 Genomic Variations in Pancreatic Cancer and Potential Opportunities for Development of New Approaches for Diagnosis and Treatment International Journal of Molecular Sciences. Jun, 2017 | Pubmed ID: 28587243 Haploinsufficiency of Hand1 Improves Mice Survival After Acute Myocardial Infarction Through Preventing Cardiac Rupture Biochemical and Biophysical Research Communications. Sep, 2016 | Pubmed ID: 27601324 The Efficacy of Oncolytic Adenovirus is Mediated by T Cell Responses Against Virus and Tumor in Syrian Hamster Model Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2016 | Pubmed ID: 27435398 CRISPR-Cas9 As a Powerful Tool for Efficient Creation of Oncolytic Viruses Viruses. Mar, 2016 | Pubmed ID: 26959050 Vaccinia Virus, a Promising New Therapeutic Agent for Pancreatic Cancer Immunotherapy. 2015 | Pubmed ID: 26595180 A Marker-free System for Highly Efficient Construction of Vaccinia Virus Vectors Using CRISPR Cas9 Molecular Therapy. Methods & Clinical Development. 2015 | Pubmed ID: 26417609 New Role of Interleukin-10 in Enhancing the Antitumor Efficacy of Oncolytic Vaccinia Virus for Treatment of Pancreatic Cancer Oncoimmunology. Sep, 2015 | Pubmed ID: 26405610 Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus Without Compromising Anticancer Activity Cancer Research. Jul, 2015 | Pubmed ID: 25977332 A Novel Compound WISP3 Mutation in a Chinese Family with Progressive Pseudorheumatoid Dysplasia Gene. Jun, 2015 | Pubmed ID: 25794430 Efficiently Editing the Vaccinia Virus Genome by Using the CRISPR-Cas9 System Journal of Virology. May, 2015 | Pubmed ID: 25741005 A Vaccinia Virus Armed with Interleukin-10 is a Promising Therapeutic Agent for Treatment of Murine Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2015 | Pubmed ID: 25416195 STAT1 Interaction with E3-14.7K in Monocytes Affects the Efficacy of Oncolytic Adenovirus Journal of Virology. Feb, 2014 | Pubmed ID: 24335311 Update on Oncolytic Viral Therapy - Targeting Angiogenesis OncoTargets and Therapy. 2013 | Pubmed ID: 23940420 Vascular Endothelial Growth Factor A Promotes Vaccinia Virus Entry into Host Cells Via Activation of the Akt Pathway Journal of Virology. Mar, 2013 | Pubmed ID: 23269798 A Novel Therapeutic Regimen to Eradicate Established Solid Tumors with an Effective Induction of Tumor-specific Immunity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2012 | Pubmed ID: 23091113 Systemic Delivery of Oncolytic Viruses: Hopes and Hurdles Advances in Virology. 2012 | Pubmed ID: 22400027 Modification of the Early Gene Enhancer-promoter Improves the Oncolytic Potency of Adenovirus 11 Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2012 | Pubmed ID: 22086234 Lister Vaccine Strain of Vaccinia Virus Armed with the Endostatin-angiostatin Fusion Gene: an Oncolytic Virus Superior to Dl1520 (ONYX-015) for Human Head and Neck Cancer Human Gene Therapy. Sep, 2011 | Pubmed ID: 21361787 PRSS3 Promotes Tumour Growth and Metastasis of Human Pancreatic Cancer Gut. Nov, 2010 | Pubmed ID: 20947888 Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles Viruses. Jan, 2010 | Pubmed ID: 20543907 Lister Strain Vaccinia Virus, a Potential Therapeutic Vector Targeting Hypoxic Tumours Gene Therapy. Feb, 2010 | Pubmed ID: 19890355 Combination of Anti-angiogenic Therapy and Virotherapy: Arming Oncolytic Viruses with Anti-angiogenic Genes Current Opinion in Molecular Therapeutics. Dec, 2009 | Pubmed ID: 20072943 Lister Strain of Vaccinia Virus Armed with Endostatin-angiostatin Fusion Gene As a Novel Therapeutic Agent for Human Pancreatic Cancer Gene Therapy. Oct, 2009 | Pubmed ID: 19587709 CEACAM6 Attenuates Adenovirus Infection by Antagonizing Viral Trafficking in Cancer Cells The Journal of Clinical Investigation. Jun, 2009 | Pubmed ID: 19411761 Enhancing Poxvirus Oncolytic Effects Through Increased Spread and Immune Evasion Cancer Research. Apr, 2008 | Pubmed ID: 18381410 Targeting of Interferon-beta to Produce a Specific, Multi-mechanistic Oncolytic Vaccinia Virus PLoS Medicine. Dec, 2007 | Pubmed ID: 18162040 Rational Strain Selection and Engineering Creates a Broad-spectrum, Systemically Effective Oncolytic Poxvirus, JX-963 The Journal of Clinical Investigation. Nov, 2007 | Pubmed ID: 17965776 Expression of the IAP Protein Family is Dysregulated in Pancreatic Cancer Cells and is Important for Resistance to Chemotherapy International Journal of Cancer. Jun, 2007 | Pubmed ID: 17311258 Activity of the Adenoviral E1A Deletion Mutant Dl922-947 in Ovarian Cancer: Comparison with E1A Wild-type Viruses, Bioluminescence Monitoring, and Intraperitoneal Delivery in Icodextrin Cancer Research. Jan, 2006 | Pubmed ID: 16424034 Virus-associated RNA I-deleted Adenovirus, a Potential Oncolytic Agent Targeting EBV-associated Tumors Cancer Research. Feb, 2005 | Pubmed ID: 15735041 A Novel Assay to Assess Primary Human Cancer Infectibility by Replication-selective Oncolytic Adenoviruses Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2005 | Pubmed ID: 15671566 Noninvasive Imaging of the Transcriptional Activities of Human Telomerase Promoter Fragments in Mice Cancer Research. Jul, 2004 | Pubmed ID: 15256462 Interleukin-1beta and Tumour Necrosis Factor-alpha Promote the Transformation of Human Immortalised Mesothelial Cells by Erionite International Journal of Oncology. Jul, 2004 | Pubmed ID: 15202003 An E1B-19 KDa Gene Deletion Mutant Adenovirus Demonstrates Tumor Necrosis Factor-enhanced Cancer Selectivity and Enhanced Oncolytic Potency Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2004 | Pubmed ID: 15194046 Quantitative Imaging of Na/I Symporter Transgene Expression Using Positron Emission Tomography in the Living Animal Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2004 | Pubmed ID: 15006611 E3 Gene Manipulations Affect Oncolytic Adenovirus Activity in Immunocompetent Tumor Models Nature Biotechnology. Nov, 2003 | Pubmed ID: 14555956 Novel Immunocompetent Murine Tumor Models for the Assessment of Replication-competent Oncolytic Adenovirus Efficacy Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2003 | Pubmed ID: 12946314 Production of Genetically Engineered Golden Syrian Hamsters by Pronuclear Injection of the CRISPR/Cas9 Complex Rong Li*1, Jinxin Miao*1,2, Zhiqiang Fan1, SeokHwan Song3, Il-keun Kong3,4, Yaohe Wang2,5, Zhongde Wang1 1Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 2National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre, School of Basic Medical Sciences, Zhengzhou University, 3Department of Animal Science Division of Applied Life Science (BK21 Plus), Gyeongsang National University, 4Institute of Agriculture and Life Science, Gyeongsang National University, 5Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London JoVE 56263 Bioengineering A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors Ming Yuan*1, Pengju Wang*2,3, Louisa S. Chard1, Nicholas R. Lemoine1,2,3, Yaohe Wang1,2,3 1Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, 2Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University, 3School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University JoVE 54171 Immunology and Infection
Production of Genetically Engineered Golden Syrian Hamsters by Pronuclear Injection of the CRISPR/Cas9 Complex Rong Li*1, Jinxin Miao*1,2, Zhiqiang Fan1, SeokHwan Song3, Il-keun Kong3,4, Yaohe Wang2,5, Zhongde Wang1 1Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 2National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre, School of Basic Medical Sciences, Zhengzhou University, 3Department of Animal Science Division of Applied Life Science (BK21 Plus), Gyeongsang National University, 4Institute of Agriculture and Life Science, Gyeongsang National University, 5Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London JoVE 56263 Bioengineering
A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors Ming Yuan*1, Pengju Wang*2,3, Louisa S. Chard1, Nicholas R. Lemoine1,2,3, Yaohe Wang1,2,3 1Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, 2Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University, 3School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University JoVE 54171 Immunology and Infection