Yatrik M. Shah Department of Molecular & Integrative Physiology University of Michigan Biography Publications Institution JoVE Articles Yatrik M. Shah has not added a biography. If you are Yatrik M. Shah and would like to personalize this page please email our Author Liaison for assistance. Publications Hypoxia-inducible Factor 1α Regulates a SOCS3-STAT3-adiponectin Signal Transduction Pathway in Adipocytes The Journal of Biological Chemistry. Feb, 2013 | Pubmed ID: 23255598 Hypoxia-inducible Factor-2α is Essential in Activating the COX2/mPGES-1/PGE2 Signaling Axis in Colon Cancer Carcinogenesis. Jan, 2013 | Pubmed ID: 23042097 Analysis of the Peroxisome Proliferator-activated Receptor-β/δ (PPARβ/δ) Cistrome Reveals Novel Co-regulatory Role of ATF4 BMC Genomics. 2012 | Pubmed ID: 23176727 Metabolomics Identifies an Inflammatory Cascade Involved in Dioxin- and Diet-induced Steatohepatitis Cell Metabolism. Nov, 2012 | Pubmed ID: 23140643 The Hypoxia-inducible Factor-C/EBPα Axis Controls Ethanol-mediated Hepcidin Repression Molecular and Cellular Biology. Oct, 2012 | Pubmed ID: 22869521 Pregnane X Receptor As a Target for Treatment of Inflammatory Bowel Disorders Trends in Pharmacological Sciences. Jun, 2012 | Pubmed ID: 22609277 Decreased Hepcidin Expression in Murine β-thalassemia is Associated with Suppression of Bmp/Smad Signaling Blood. Mar, 2012 | Pubmed ID: 22461476 Hypoxia-inducible Factor-2α Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis Cancer Research. May, 2012 | Pubmed ID: 22419665 Peroxisome Proliferator-activated Receptor Alpha Induction of Uncoupling Protein 2 Protects Against Acetaminophen-induced Liver Toxicity Hepatology (Baltimore, Md.). Jul, 2012 | Pubmed ID: 22318764 The Role of Peroxisome Proliferator-activated Receptors in Carcinogenesis and Chemoprevention Nature Reviews. Cancer. Mar, 2012 | Pubmed ID: 22318237 Disruption of Endothelial Peroxisome Proliferator-activated Receptor γ Accelerates Diet-induced Atherogenesis in LDL Receptor-null Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2012 | Pubmed ID: 22015658 Disruption of Hypoxia-inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-fat Diet-fed Mice Diabetes. Oct, 2011 | Pubmed ID: 21873554 Hypoxia-inducible Transcription Factor 2α Promotes Steatohepatitis Through Augmenting Lipid Accumulation, Inflammation, and Fibrosis Hepatology (Baltimore, Md.). Aug, 2011 | Pubmed ID: 21538443 Intestinal Hypoxia-inducible Factor-2alpha (HIF-2alpha) is Critical for Efficient Erythropoiesis The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21498508 Fibrinogen-γ Proteolysis and Solubility Dynamics During Apoptotic Mouse Liver Injury: Heparin Prevents and Treats Liver Damage Hepatology (Baltimore, Md.). Apr, 2011 | Pubmed ID: 21480334 Hypoxia-inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice Gastroenterology. Jun, 2011 | Pubmed ID: 21419768 PPARalpha-dependent Activation of Cell Cycle Control and DNA Repair Genes in Hepatic Nonparenchymal Cells Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2010 | Pubmed ID: 20813756 Therapeutic Role of Rifaximin in Inflammatory Bowel Disease: Clinical Implication of Human Pregnane X Receptor Activation The Journal of Pharmacology and Experimental Therapeutics. Oct, 2010 | Pubmed ID: 20627999 Control of Steroid 21-oic Acid Synthesis by Peroxisome Proliferator-activated Receptor Alpha and Role of the Hypothalamic-pituitary-adrenal Axis The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 20032461 Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid Beta-oxidation Through the Suppression of PPARalpha Activation As a Contributing Mechanism of Acetaminophen-induced Hepatotoxicity Chemical Research in Toxicology. Apr, 2009 | Pubmed ID: 19256530 Intestinal Hypoxia-inducible Transcription Factors Are Essential for Iron Absorption Following Iron Deficiency Cell Metabolism. Feb, 2009 | Pubmed ID: 19147412 A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4 Drug Metabolism and Disposition: the Biological Fate of Chemicals. Dec, 2008 | Pubmed ID: 18799805 Hypoxia-inducible Factor Augments Experimental Colitis Through an MIF-dependent Inflammatory Signaling Cascade Gastroenterology. Jun, 2008 | Pubmed ID: 18439915 Hepatocyte Nuclear Factor 4alpha in the Intestinal Epithelial Cells Protects Against Inflammatory Bowel Disease Inflammatory Bowel Diseases. Jul, 2008 | Pubmed ID: 18338782 Metabolomics Reveals That Hepatic Stearoyl-CoA Desaturase 1 Downregulation Exacerbates Inflammation and Acute Colitis Cell Metabolism. Feb, 2008 | Pubmed ID: 18249173 PPARalpha: Mechanism of Species Differences and Hepatocarcinogenesis of Peroxisome Proliferators Toxicology. Apr, 2008 | Pubmed ID: 18006136 Pioglitazone Increases Macrophage Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Nondiabetic Low-density Lipoprotein Receptor-null Mice Circulation. Nov, 2007 | Pubmed ID: 17967777 Rifaximin is a Gut-specific Human Pregnane X Receptor Activator The Journal of Pharmacology and Experimental Therapeutics. Jul, 2007 | Pubmed ID: 17442842 Peroxisome Proliferator-activated Receptor Alpha Regulates a MicroRNA-mediated Signaling Cascade Responsible for Hepatocellular Proliferation Molecular and Cellular Biology. Jun, 2007 | Pubmed ID: 17438130 Pregnane X Receptor Activation Ameliorates DSS-induced Inflammatory Bowel Disease Via Inhibition of NF-kappaB Target Gene Expression American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2007 | Pubmed ID: 17170021 Expression of Peroxisome Proliferator-activated Receptor-gamma in Macrophage Suppresses Experimentally Induced Colitis American Journal of Physiology. Gastrointestinal and Liver Physiology. Feb, 2007 | Pubmed ID: 17095756 Identification of Novel Proteins Induced by Estradiol, 4-hydroxytamoxifen and Acolbifene in T47D Breast Cancer Cells Steroids. Nov, 2006 | Pubmed ID: 16949628 Attenuation of Estrogen Receptor Alpha (ERalpha) Signaling by Selenium in Breast Cancer Cells Via Downregulation of ERalpha Gene Expression Breast Cancer Research and Treatment. Aug, 2005 | Pubmed ID: 16155795 Selenium Disrupts Estrogen Receptor (alpha) Signaling and Potentiates Tamoxifen Antagonism in Endometrial Cancer Cells and Tamoxifen-resistant Breast Cancer Cells Molecular Cancer Therapeutics. Aug, 2005 | Pubmed ID: 16093440 The Src Kinase Pathway Promotes Tamoxifen Agonist Action in Ishikawa Endometrial Cells Through Phosphorylation-dependent Stabilization of Estrogen Receptor (alpha) Promoter Interaction and Elevated Steroid Receptor Coactivator 1 Activity Molecular Endocrinology (Baltimore, Md.). Mar, 2005 | Pubmed ID: 15528270 Selective Estrogen Receptor Modulator Regulated Proteins in Endometrial Cancer Cells Molecular and Cellular Endocrinology. Apr, 2004 | Pubmed ID: 15149734 В пробирке Organoid культуры первичных опухолей толстой мыши Xiang Xue1, Yatrik M. Shah1,2 1Department of Molecular & Integrative Physiology, University of Michigan, 2Department of Internal Medicine, Division of Gastroenterology, University of Michigan JoVE 50210 Medicine
В пробирке Organoid культуры первичных опухолей толстой мыши Xiang Xue1, Yatrik M. Shah1,2 1Department of Molecular & Integrative Physiology, University of Michigan, 2Department of Internal Medicine, Division of Gastroenterology, University of Michigan JoVE 50210 Medicine