Yuri Sykulev Departments of Microbiology and Immunology and Medical Oncology, Sidney Kimmel Cancer Center Thomas Jefferson University Biography Publications Institution JoVE Articles Yuri Sykulev has not added a biography. If you are Yuri Sykulev and would like to personalize this page please email our Author Liaison for assistance. Publications Limited Immune Surveillance in Lymphoid Tissue by Cytolytic CD4+ T Cells During Health and HIV Disease PLoS Pathogens. 04, 2018 | Pubmed ID: 29652923 Evaluating Frequency and Quality of Pathogen-specific T Cells Nature Communications. Oct, 2016 | Pubmed ID: 27786275 Integrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent Manner The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25778396 Herman N. Eisen: Mentor to Many Proceedings of the National Academy of Sciences of the United States of America. Feb, 2015 | Pubmed ID: 25617368 Core-based Lipid Nanoparticles As a Nanoplatform for Delivery of Near-infrared Fluorescent Imaging Agents American Journal of Nuclear Medicine and Molecular Imaging. 2014 | Pubmed ID: 25250201 Integrin Receptors on Tumor Cells Facilitate NK Cell-mediated Antibody-dependent Cytotoxicity European Journal of Immunology. Aug, 2014 | Pubmed ID: 24810893 Evidence That the Density of Self Peptide-MHC Ligands Regulates T-cell Receptor Signaling PloS One. 2012 | Pubmed ID: 22870225 Enteric Alpha Defensins in Norm and Pathology Annals of Clinical Microbiology and Antimicrobials. Jan, 2012 | Pubmed ID: 22236533 Mechanisms Controlling Granule-mediated Cytolytic Activity of Cytotoxic T Lymphocytes Immunologic Research. Dec, 2011 | Pubmed ID: 22058021 Changing Separating Distances Between Immune Receptors As a Sensitive Mechanism Regulating T-cell Activation Self/nonself. Jan, 2010 | Pubmed ID: 21318086 T Cell Receptor Signaling Kinetics Takes the Stage Science Signaling. Dec, 2010 | Pubmed ID: 21177491 A Novel Composite Immunotoxin That Suppresses Rabies Virus Production by the Infected Cells Journal of Immunological Methods. Feb, 2010 | Pubmed ID: 19932697 Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain Immunity. Oct, 2009 | Pubmed ID: 19833088 Can Oligomeric T-cell Receptor Be Used As a Tool to Detect Viral Peptide Epitopes on Infected Cells? Clinical Immunology (Orlando, Fla.). Jan, 2009 | Pubmed ID: 18845488 Protein Kinase C Theta Regulates Stability of the Peripheral Adhesion Ring Junction and Contributes to the Sensitivity of Target Cell Lysis by CTL Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18802085 How a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound Peptide The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18703505 Tpl2 and ERK Transduce Antiproliferative T Cell Receptor Signals and Inhibit Transformation of Chronically Stimulated T Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18287049 Quantum Dot/peptide-MHC Biosensors Reveal Strong CD8-dependent Cooperation Between Self and Viral Antigens That Augment the T Cell Response Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17077145 Antagonism of HIV-specific CD4+ T Cells by C-terminal Truncation of a Minimum Epitope Molecular Immunology. Mar, 2006 | Pubmed ID: 16216327 ICAM-1 Co-stimulates Target Cells to Facilitate Antigen Presentation Current Opinion in Immunology. Jun, 2005 | Pubmed ID: 15886114 Distinct Role of Lymphocyte Function-associated Antigen-1 in Mediating Effective Cytolytic Activity by Cytotoxic T Lymphocytes Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15851656 Major Histocompatibility Complex Class I-intercellular Adhesion Molecule-1 Association on the Surface of Target Cells: Implications for Antigen Presentation to Cytotoxic T Lymphocytes Immunology. Dec, 2004 | Pubmed ID: 15554924 Antibody Specific for the Peptide.major Histocompatibility Complex. Is It T Cell Receptor-like? The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15302863 Cytotoxic T Lymphocytes Form an Antigen-independent Ring Junction The Journal of Clinical Investigation. Jan, 2004 | Pubmed ID: 14702108 Soluble HIV-specific T Cell Receptor: Expression, Purification and Analysis of the Specificity Journal of Immunological Methods. Jun, 2003 | Pubmed ID: 12799041 Distinct Molecular Mechanisms Account for the Specificity of Two Different T-cell Receptors Biochemistry. Apr, 2003 | Pubmed ID: 12705834 Differential Splicing Generates Tvl-1/RFXANK Isoforms with Different Functions The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12215433 Multiple Effector Functions Mediated by Human Immunodeficiency Virus-specific CD4(+) T-cell Clones Journal of Virology. Oct, 2001 | Pubmed ID: 11559810 परिधीय रक्त और लसीकावत् ऊतक से प्राथमिक मानव टी कोशिकाओं के Synaptic इंटरफेस का आकलन Maria Steblyanko1, Nadia Anikeeva1, Marcus Buggert2,3, Michael R. Betts2, Yuri Sykulev4 1Department of Microbiology and Immunology, Thomas Jefferson University, 2Department of Microbiology and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, 3Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, 4Departments of Microbiology and Immunology and Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University JoVE 58143 Immunology and Infection
परिधीय रक्त और लसीकावत् ऊतक से प्राथमिक मानव टी कोशिकाओं के Synaptic इंटरफेस का आकलन Maria Steblyanko1, Nadia Anikeeva1, Marcus Buggert2,3, Michael R. Betts2, Yuri Sykulev4 1Department of Microbiology and Immunology, Thomas Jefferson University, 2Department of Microbiology and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, 3Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, 4Departments of Microbiology and Immunology and Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University JoVE 58143 Immunology and Infection