Zhong Huang Department of Biochemistry and Molecular Biology The University of Texas Medical School at Houston Biography Publications Institution JoVE Articles Zhong Huang has not added a biography. If you are Zhong Huang and would like to personalize this page please email our Author Liaison for assistance. Publications IL-33/ST2-mediated Inflammation in Macrophages is Directly Abrogated by IL-10 During Rheumatoid Arthritis Oncotarget. Mar, 2017 | Pubmed ID: 28415811 Interleukin-18 Protects Mice from Enterovirus 71 Infection Cytokine. Apr, 2017 | Pubmed ID: 28399485 Immunization with a Subunit Hepatitis C Virus Vaccine Elicits Pan-genotypic Neutralizing Antibodies and Intra-hepatic T-cell Responses in Non-human Primates The Journal of Infectious Diseases. Apr, 2017 | Pubmed ID: 28398489 Generation of Induced Cardiac Progenitor Cells Via Somatic Reprogramming Oncotarget. Apr, 2017 | Pubmed ID: 28199972 Beta-Propiolactone Inactivation of Coxsackievirus A16 Induces Structural Alteration and Surface Modification of Viral Capsids Journal of Virology. Apr, 2017 | Pubmed ID: 28148783 Transcutaneous Immunization Via Rapidly Dissolvable Microneedles Protects Against Hand-foot-and-mouth Disease Caused by Enterovirus 71 Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2016 | Pubmed ID: 27793685 Gate-tunable Negative Longitudinal Magnetoresistance in the Predicted Type-II Weyl Semimetal WTe2 Nature Communications. Oct, 2016 | Pubmed ID: 27725682 Molecular Epidemiology of Human Enterovirus 71 at the Origin of an Epidemic of Fatal Hand, Foot and Mouth Disease Cases in Cambodia Emerging Microbes & Infections. Sep, 2016 | Pubmed ID: 27651091 Altered Glycosylation Patterns Increase Immunogenicity of a Subunit Hepatitis C Virus Vaccine, Inducing Neutralizing Antibodies Which Confer Protection in Mice Journal of Virology. Dec, 2016 | Pubmed ID: 27630242 Inactivated Coxsackievirus A10 Experimental Vaccines Protect Mice Against Lethal Viral Challenge Vaccine. Sep, 2016 | Pubmed ID: 27562093 Highly Efficient Metallic Optical Incouplers for Quantum Well Infrared Photodetectors Scientific Reports. Jul, 2016 | Pubmed ID: 27456691 An Ebola Virus-Like Particle-Based Reporter System Enables Evaluation of Antiviral Drugs In Vivo Under Non-Biosafety Level 4 Conditions Journal of Virology. Oct, 2016 | Pubmed ID: 27440895 Virus-like Particle-based Vaccine Against Coxsackievirus A6 Protects Mice Against Lethal Infections Vaccine. Jul, 2016 | Pubmed ID: 27340093 Yeast-produced Recombinant Virus-like Particles of Coxsackievirus A6 Elicited Protective Antibodies in Mice Antiviral Research. Aug, 2016 | Pubmed ID: 27315772 A Modular Vaccine Development Platform Based on Sortase-Mediated Site-Specific Tagging of Antigens Onto Virus-Like Particles Scientific Reports. May, 2016 | Pubmed ID: 27170066 Cloning and Expression Analysis of C-type Lysozyme Gene in Golden Pompano, Trachinotus Ovatus Fish & Shellfish Immunology. Jul, 2016 | Pubmed ID: 27150051 Construction of Nontoxic Polymeric UV-Absorber with Great Resistance to UV-Photoaging Scientific Reports. May, 2016 | Pubmed ID: 27138547 Improved Plasmid-based Recovery of Coxsackievirus A16 Infectious Clone Driven by Human RNA Polymerase I Promoter Virologica Sinica. Aug, 2016 | Pubmed ID: 27113242 Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody PLoS Pathogens. Mar, 2016 | Pubmed ID: 26938634 Coxsackievirus A16-like Particles Produced in Pichia Pastoris Elicit High-titer Neutralizing Antibodies and Confer Protection Against Lethal Viral Challenge in Mice Antiviral Research. May, 2016 | Pubmed ID: 26902108 Erratum To: First Molecular Detection of Porcine Circovirus Type 2 in Bovids in China Virus Genes. Feb, 2016 | Pubmed ID: 26578152 [RESEARCH PROGRESS OF AUTOLOGOUS VEIN NERVE CONDUIT FOR REPAIR OF PERIPHERAL NERVE DEFECT] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. Nov, 2015 | Pubmed ID: 26875283 Effects of Dietary Soybean Isoflavones on Non-specific Immune Responses and Hepatic Antioxidant Abilities and MRNA Expression of Two Heat Shock Proteins (HSPs) in Juvenile Golden Pompano Trachinotus Ovatus Under PH Stress Fish & Shellfish Immunology. Dec, 2015 | Pubmed ID: 26518502 A Bivalent Virus-like Particle Based Vaccine Induces a Balanced Antibody Response Against Both Enterovirus 71 and Norovirus in Mice Vaccine. Oct, 2015 | Pubmed ID: 26424606 Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit Both Virus Attachment and Internalization During Viral Entry Journal of Virology. Dec, 2015 | Pubmed ID: 26401034 Antibodies to P-selectin Glycoprotein Ligand-1 Block Dendritic Cell-mediated Enterovirus 71 Transmission and Prevent Virus-induced Cells Death Virulence. 2015 | Pubmed ID: 26399965 IL-37 Restrains Autoimmune Diseases Oncotarget. Sep, 2015 | Pubmed ID: 26296977 Hexon-modified Recombinant E1-deleted Adenoviral Vectors As Bivalent Vaccine Carriers for Coxsackievirus A16 and Enterovirus 71 Vaccine. Sep, 2015 | Pubmed ID: 26296491 MTOR Regulates TLR-induced C-fos and Th1 Responses to HBV and HCV Vaccines Virologica Sinica. Jun, 2015 | Pubmed ID: 26122641 Reciprocal Regulation Between Enterovirus 71 and the NLRP3 Inflammasome Cell Reports. Jul, 2015 | Pubmed ID: 26119741 Augmented Carbohydrate Oxidation Under Moderate Hypobaric Hypoxia Equivalent to Simulated Altitude of 2500 M The Tohoku Journal of Experimental Medicine. 2015 | Pubmed ID: 26072915 Phylogenetic Analysis of the Major Causative Agents of Hand, Foot and Mouth Disease in Suzhou City, Jiangsu Province, China, in 2012-2013 Emerging Microbes & Infections. Feb, 2015 | Pubmed ID: 26038764 IL-37 Alleviates Rheumatoid Arthritis by Suppressing IL-17 and IL-17-Triggering Cytokine Production and Limiting Th17 Cell Proliferation Journal of Immunology (Baltimore, Md. : 1950). Jun, 2015 | Pubmed ID: 25917106 High-yield Production of Recombinant Virus-like Particles of Enterovirus 71 in Pichia Pastoris and Their Protective Efficacy Against Oral Viral Challenge in Mice Vaccine. May, 2015 | Pubmed ID: 25820068 Interleukin-37 is Increased in Ankylosing Spondylitis Patients and Associated with Disease Activity Journal of Translational Medicine. Jan, 2015 | Pubmed ID: 25627863 Effects of Dietary Chlorogenic Acid on Growth Performance, Antioxidant Capacity of White Shrimp Litopenaeus Vannamei Under Normal Condition and Combined Stress of Low-salinity and Nitrite Fish & Shellfish Immunology. Apr, 2015 | Pubmed ID: 25600509 The Effects of Dietary Soybean Isoflavones on Growth, Innate Immune Responses, Hepatic Antioxidant Abilities and Disease Resistance of Juvenile Golden Pompano Trachinotus Ovatus Fish & Shellfish Immunology. Mar, 2015 | Pubmed ID: 25541076 Towards Broadly Protective Polyvalent Vaccines Against Hand, Foot and Mouth Disease Microbes and Infection. Feb, 2015 | Pubmed ID: 25449959 Effects of Resistance Training Under Hypoxic Conditions on Muscle Hypertrophy and Strength Clinical Physiology and Functional Imaging. May, 2015 | Pubmed ID: 24690432 Spatial Patterns and Associations Between Species Belonging to Four Genera of the Lauraceae Family PloS One. 2014 | Pubmed ID: 25365507 Catabolism of (2E)-4-hydroxy-2-nonenal Via ω- and ω-1-oxidation Stimulated by Ketogenic Diet The Journal of Biological Chemistry. Nov, 2014 | Pubmed ID: 25274632 First Molecular Detection of Porcine Circovirus Type 2 in Bovids in China Virus Genes. Dec, 2014 | Pubmed ID: 25248785 Increased Expression of IL-37 in Patients with Graves' Disease and Its Contribution to Suppression of Proinflammatory Cytokines Production in Peripheral Blood Mononuclear Cells PloS One. 2014 | Pubmed ID: 25226272 Fighting Ebola with ZMapp: Spotlight on Plant-made Antibody Science China. Life Sciences. Oct, 2014 | Pubmed ID: 25218825 A Virus-like Particle Based Bivalent Vaccine Confers Dual Protection Against Enterovirus 71 and Coxsackievirus A16 Infections in Mice Vaccine. Jul, 2014 | Pubmed ID: 24950363 Which Models Are Appropriate for Six Subtropical Forests: Species-area and Species-abundance Models PloS One. 2014 | Pubmed ID: 24755956 Interleukin-10 Attenuation of Collagen-induced Arthritis is Associated with Suppression of Interleukin-17 and Retinoid-related Orphan Receptor γt Production in Macrophages and Repression of Classically Activated Macrophages Arthritis Research & Therapy. Apr, 2014 | Pubmed ID: 24742125 Design and Fabrication of Carbon Quantum Dots/TiO2 Photonic Crystal Complex with Enhanced Photocatalytic Activity Journal of Nanoscience and Nanotechnology. Jun, 2014 | Pubmed ID: 24738364 A Combination Vaccine Comprising of Inactivated Enterovirus 71 and Coxsackievirus A16 Elicits Balanced Protective Immunity Against Both Viruses Vaccine. May, 2014 | Pubmed ID: 24657161 IL-37 Inhibits the Production of Inflammatory Cytokines in Peripheral Blood Mononuclear Cells of Patients with Systemic Lupus Erythematosus: Its Correlation with Disease Activity Journal of Translational Medicine. Mar, 2014 | Pubmed ID: 24629023 The Molecule of DC-SIGN Captures Enterovirus 71 and Confers Dendritic Cell-mediated Viral Trans-infection Virology Journal. Mar, 2014 | Pubmed ID: 24620896 A Murine Model of Coxsackievirus A16 Infection for Anti-viral Evaluation Antiviral Research. May, 2014 | Pubmed ID: 24583030 Chimeric Virus-like Particle Vaccines Displaying Conserved Enterovirus 71 Epitopes Elicit Protective Neutralizing Antibodies in Mice Through Divergent Mechanisms Journal of Virology. Jan, 2014 | Pubmed ID: 24131712 Sulforaphane Enhances the Ability of Human Retinal Pigment Epithelial Cell Against Oxidative Stress, and Its Effect on Gene Expression Profile Evaluated by Microarray Analysis Oxidative Medicine and Cellular Longevity. 2013 | Pubmed ID: 24187606 Bacterial Immune Interaction in Experimental Colitis Journal of Digestive Diseases. Oct, 2013 | Pubmed ID: 23734583 Active Immunization with a Coxsackievirus A16 Experimental Inactivated Vaccine Induces Neutralizing Antibodies and Protects Mice Against Lethal Infection Vaccine. Apr, 2013 | Pubmed ID: 23499596 Identification of Conserved Neutralizing Linear Epitopes Within the VP1 Protein of Coxsackievirus A16 Vaccine. Apr, 2013 | Pubmed ID: 23499595 Neutralizing Antibodies Induced by Recombinant Virus-like Particles of Enterovirus 71 Genotype C4 Inhibit Infection at Pre- and Post-attachment Steps PloS One. 2013 | Pubmed ID: 23451250 Oral Antigens Induce Rheumatoid Arthritis-like Inflammation in a Rat Model Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]. Mar, 2013 | Pubmed ID: 23229722 Characterization of Enterovirus 71 Capsids Using Subunit Protein-specific Polyclonal Antibodies Journal of Virological Methods. Jan, 2013 | Pubmed ID: 23046991 Immunomodulatory Effects of Crude Phenylethanoid Glycosides from Ligustrum Purpurascens Journal of Ethnopharmacology. Dec, 2012 | Pubmed ID: 23064286 A Virus-like Particle Vaccine for Coxsackievirus A16 Potently Elicits Neutralizing Antibodies That Protect Mice Against Lethal Challenge Vaccine. Oct, 2012 | Pubmed ID: 22959985 Development of Murine Monoclonal Antibodies with Potent Neutralization Effects on Enterovirus 71 Journal of Virological Methods. Dec, 2012 | Pubmed ID: 22771741 Dietary Values of Astaxanthin and Canthaxanthin in Penaeus Monodon in the Presence and Absence of Cholesterol Supplementation: Effect on Growth, Nutrient Digestibility and Tissue Carotenoid Composition The British Journal of Nutrition. Jul, 2012 | Pubmed ID: 22142867 Combined Blood Purification for Treating Acute Fatty Liver of Pregnancy Complicated by Acute Kidney Injury: a Case Series Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs. Jun, 2012 | Pubmed ID: 22120164 Phosphorylated Smooth Muscle Heavy Meromyosin Shows an Open Conformation Linked to Activation Journal of Molecular Biology. Jan, 2012 | Pubmed ID: 22079364 Construction and Characterization of an Infectious Clone of Coxsackievirus A16 Virology Journal. Dec, 2011 | Pubmed ID: 22165961 [Expression of VP0 Protein of Enterovirus 71 in Escherichia Coli and Generation of the Corresponding Polyclonal Antibodies in Guinea Pigs] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. May, 2011 | Pubmed ID: 21557912 Single-particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells Small (Weinheim an Der Bergstrasse, Germany). May, 2011 | Pubmed ID: 21456082 Detection, Characterization and Quantitation of Coxsackievirus A16 Using Polyclonal Antibodies Against Recombinant Capsid Subunit Proteins Journal of Virological Methods. Apr, 2011 | Pubmed ID: 21295614 [Cloning and Expression of a Fragment of Corylus Heterophylla 1 and Identifying Its Immunologic Competence] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Jan, 2011 | Pubmed ID: 21208553 [4 + 3] Cycloaddition of Aromatic α,β-unsaturated Aldehydes and Ketones with Epoxides: One-step Approach to Synthesize Seven-membered Oxacycles Catalyzed by Lewis Acid The Journal of Organic Chemistry. Jan, 2011 | Pubmed ID: 21192645 Isolation and Genetic Analysis of a Novel Triple-reassortant H1N1 Influenza Virus from a Pig in China Veterinary Microbiology. Jan, 2011 | Pubmed ID: 20708352 Light-induced Tyrosine Phosphorylation of Rod Outer Segment Membrane Proteins Regulate the Translocation, Membrane Binding and Activation of Type II α Phosphatidylinositol-5-phosphate 4-kinase Neurochemical Research. Apr, 2011 | Pubmed ID: 20204506 Immune Protection Induced on Day 10 Following Administration of the 2009 A/H1N1 Pandemic Influenza Vaccine PloS One. 12, 2010 | Pubmed ID: 21151563 High-level Rapid Production of Full-size Monoclonal Antibodies in Plants by a Single-vector DNA Replicon System Biotechnology and Bioengineering. May, 2010 | Pubmed ID: 20047189 Bis(2,2-dinitro-prop-yl)formal Acta Crystallographica. Section E, Structure Reports Online. Mar, 2009 | Pubmed ID: 21582607 A DNA Replicon System for Rapid High-level Production of Virus-like Particles in Plants Biotechnology and Bioengineering. Jul, 2009 | Pubmed ID: 19309755 Rubisco in Complex with Rubisco Large Subunit Methyltransferase Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19208805 Cytokine MRNA Expression in Painful Radiculopathy The Journal of Pain : Official Journal of the American Pain Society. Jan, 2009 | Pubmed ID: 18848809 [Study of the 482G/A Variation in PGC-1alpha Gene Domain MEF2C As Possible Mechanism of Type 2 Diabetes] Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics. Dec, 2008 | Pubmed ID: 19065516 Deletion of a Splicing Enhancer Disrupts PLP1/DM20 Ratio and Myelin Stability Experimental Neurology. Dec, 2008 | Pubmed ID: 18835559 [Effect of Sodium Ferulate on Hemodynamics in Hepatic Cirrhosis Patients with Portal Hypertension] Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine. Jul, 2008 | Pubmed ID: 18822917 An Efficient Plant Viral Expression System Generating Orally Immunogenic Norwalk Virus-like Particles Vaccine. Mar, 2008 | Pubmed ID: 18325641 Structural Organization of the Anaphase-promoting Complex Bound to the Mitotic Activator Slp1 Molecular Cell. Dec, 2007 | Pubmed ID: 18082611 [The CSNPs Analysis in Whole Extron-wide of PGC-1alpha Gene in Chinese Population and the Domain MEF2C Bioinformatics Study] Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics. Aug, 2007 | Pubmed ID: 17680531 Id1, but Not Id3, Directs Long-term Repopulating Hematopoietic Stem-cell Maintenance Blood. Oct, 2007 | Pubmed ID: 17622570 Biochemical Alterations in the Retinas of Very Low-density Lipoprotein Receptor Knockout Mice: an Animal Model of Retinal Angiomatous Proliferation Archives of Ophthalmology (Chicago, Ill. : 1960). Jun, 2007 | Pubmed ID: 17562991 Delay of Photoreceptor Degeneration in Tubby Mouse by Sulforaphane Journal of Neurochemistry. May, 2007 | Pubmed ID: 17394579 SPARX, a New Environment for Cryo-EM Image Processing Journal of Structural Biology. Jan, 2007 | Pubmed ID: 16931051 Virus-like Particles Production in Green Plants Methods (San Diego, Calif.). Sep, 2006 | Pubmed ID: 16997715 [pcDPG Parathyroid Hormone Gene Therapy of Hypoparathyroidism: an Experimental Study] Zhonghua Yi Xue Za Zhi. Jan, 2006 | Pubmed ID: 16677507 The Endosome-associated Protein Hrs is Hexameric and Controls Cargo Sorting As a "master Molecule" Structure (London, England : 1993). Apr, 2006 | Pubmed ID: 16615908 Plant-derived Vaccines: a Look Back at the Highlights and a View to the Challenges on the Road Ahead Expert Review of Vaccines. Apr, 2006 | Pubmed ID: 16608424 Rapid, High-level Production of Hepatitis B Core Antigen in Plant Leaf and Its Immunogenicity in Mice Vaccine. Mar, 2006 | Pubmed ID: 16417953 PLP1 Alternative Splicing in Differentiating Oligodendrocytes: Characterization of an Exonic Splicing Enhancer Journal of Cellular Biochemistry. Apr, 2006 | Pubmed ID: 16288477 Splice-site Contribution in Alternative Splicing of PLP1 and DM20: Molecular Studies in Oligodendrocytes Human Mutation. Jan, 2006 | Pubmed ID: 16287154 [Establishing the Norm of Cognitive Adaptive Test/clinical Linguistic and Auditory Milestone Scale in the Children from 4 to 36 Months of Age in Shanghai, China] Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics. Oct, 2005 | Pubmed ID: 16255861 Virus-like Particle Expression and Assembly in Plants: Hepatitis B and Norwalk Viruses Vaccine. Mar, 2005 | Pubmed ID: 15734055 Structure of the F58W Mutant of Cytochrome B5: the Mutation Leads to Multiple Conformations and Weakens Stacking Interactions Acta Crystallographica. Section D, Biological Crystallography. Feb, 2005 | Pubmed ID: 15681869 Conformational Analysis of Hepatitis B Surface Antigen Fusions in an Agrobacterium-mediated Transient Expression System Plant Biotechnology Journal. May, 2004 | Pubmed ID: 17147615 Notch-induced E2A Degradation Requires CHIP and Hsc70 As Novel Facilitators of Ubiquitination Molecular and Cellular Biology. Oct, 2004 | Pubmed ID: 15456869 Application of Template Matching Technique to Particle Detection in Electron Micrographs Journal of Structural Biology. Jan-Feb, 2004 | Pubmed ID: 15065671 Sequence, Distribution and Quantification of the Motilin Precursor in the Cat Peptides. Sep, 2003 | Pubmed ID: 14706554 Automated Determination of Parameters Describing Power Spectra of Micrograph Images in Electron Microscopy Journal of Structural Biology. Oct-Nov, 2003 | Pubmed ID: 14643211 Performance of a 41 X 41 Cm2 Amorphous Silicon Flat Panel X-ray Detector Designed for Angiographic and R&F Imaging Applications Medical Physics. Oct, 2003 | Pubmed ID: 14596310 Construction of Alpha-alpha Domains Structure in Recombinant Monkey Metallothionein-1 Journal of Inorganic Biochemistry. Nov, 2002 | Pubmed ID: 12433427 A PLP Splicing Abnormality is Associated with an Unusual Presentation of PMD Annals of Neurology. Oct, 2002 | Pubmed ID: 12325077 Structures of V45E and V45Y Mutants and Structure Comparison of a Variety of Cytochrome B5 Mutants Acta Crystallographica. Section D, Biological Crystallography. Aug, 2002 | Pubmed ID: 12136141 How to Describe Protein Motion Without Amino Acid Sequence and Atomic Coordinates Proceedings of the National Academy of Sciences of the United States of America. Jun, 2002 | Pubmed ID: 12084922 Down-regulation of the Retinoblastoma Protein (rb) is Associated with Rat Oligodendrocyte Differentiation Molecular and Cellular Neurosciences. Feb, 2002 | Pubmed ID: 11860277 Análise de uma única partícula de alta resolução a partir de imagens de crio-microscopia de elétrons usando SPHIRE Toshio Moriya1, Michael Saur1, Markus Stabrin1, Felipe Merino1, Horatiu Voicu2, Zhong Huang2, Pawel A. Penczek2, Stefan Raunser1, Christos Gatsogiannis1 1Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, 2Department of Biochemistry and Molecular Biology, The University of Texas Medical School at Houston JoVE 55448 Biochemistry
Análise de uma única partícula de alta resolução a partir de imagens de crio-microscopia de elétrons usando SPHIRE Toshio Moriya1, Michael Saur1, Markus Stabrin1, Felipe Merino1, Horatiu Voicu2, Zhong Huang2, Pawel A. Penczek2, Stefan Raunser1, Christos Gatsogiannis1 1Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, 2Department of Biochemistry and Molecular Biology, The University of Texas Medical School at Houston JoVE 55448 Biochemistry