Zsolt Bagi Vascular Biology Center Georgia Regents University Biography Publications Institution JoVE Articles Zsolt Bagi has not added a biography. If you are Zsolt Bagi and would like to personalize this page please email our Author Liaison for assistance. Publications Impaired Coronary Collateral Growth: MiR-shaken Neutrophils Caught in the Act American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2015 | Pubmed ID: 25910807 Caveolin-1 Prevents Sustained Angiotensin II-induced Resistance Artery Constriction and Obesity-induced High Blood Pressure American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2015 | Pubmed ID: 25527780 A Novel Tumor Necrosis Factor-mediated Mechanism of Direct Epithelial Sodium Channel Activation American Journal of Respiratory and Critical Care Medicine. Sep, 2014 | Pubmed ID: 25029038 Obesity and Coronary Microvascular Disease - Implications for Adipose Tissue-mediated Remote Inflammatory Response Current Vascular Pharmacology. May, 2014 | Pubmed ID: 24846234 Caveolin-1 is a Negative Regulator of NADPH Oxidase-derived Reactive Oxygen Species Free Radical Biology & Medicine. Aug, 2014 | Pubmed ID: 24835767 Age-related Impairment of Conducted Dilation in Human Coronary Arterioles American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2014 | Pubmed ID: 24778172 Prevention and Treatment of No-reflow Phenomenon by Targeting the Coronary Microcirculation Reviews in Cardiovascular Medicine. 2014 | Pubmed ID: 24762465 Peroxynitrite Disrupts Endothelial Caveolae Leading to ENOS Uncoupling and Diminished Flow-mediated Dilation in Coronary Arterioles of Diabetic Patients Diabetes. Apr, 2014 | Pubmed ID: 24353182 L-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice Frontiers in Immunology. 2013 | Pubmed ID: 24400007 Levosimendan and Its Metabolite OR-1896 Elicit KATP Channel-dependent Dilation in Resistance Arteries in Vivo Pharmacological Reports : PR. 2013 | Pubmed ID: 24399726 Effect of a Novel Stobadine Derivative on Isolated Rat Arteries Interdisciplinary Toxicology. Jun, 2013 | Pubmed ID: 24179430 Selective Up-regulation of Arginase-1 in Coronary Arteries of Diabetic Patients Frontiers in Immunology. 2013 | Pubmed ID: 24133491 Obesity and Statins Are Both Independent Predictors of Enhanced Coronary Arteriolar Dilation in Patients Undergoing Heart Surgery Journal of Cardiothoracic Surgery. 2013 | Pubmed ID: 23631400 Increased Tissue Angiotensin-converting Enzyme Activity Impairs Bradykinin-induced Dilation of Coronary Arterioles in Obesity Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 23603844 Endothelial Regulation of Coronary Microcirculation in Health and Cardiometabolic Diseases Internal and Emergency Medicine. Apr, 2013 | Pubmed ID: 23494539 Exacerbation of Endothelial Dysfunction During the Progression of Diabetes: Role of Oxidative Stress American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2012 | Pubmed ID: 22262308 Activation of Hexosamine Pathway Impairs Nitric Oxide (NO)-dependent Arteriolar Dilations by Increased Protein O-GlcNAcylation Vascular Pharmacology. Mar-Apr, 2012 | Pubmed ID: 22155161 Microvascular Responsiveness in Obesity: Implications for Therapeutic Intervention British Journal of Pharmacology. Feb, 2012 | Pubmed ID: 21797844 Molecular Imaging with Optical Coherence Tomography Using Ligand-conjugated Microparticles That Detect Activated Endothelial Cells: Rational Design Through Target Quantification Atherosclerosis. Dec, 2011 | Pubmed ID: 21872249 Increased Availability of Angiotensin AT 1 Receptors Leads to Sustained Arterial Constriction to Angiotensin II in Diabetes - Role for Rho-kinase Activation British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21385178 Arginase 1 Contributes to Diminished Coronary Arteriolar Dilation in Patients with Diabetes American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2011 | Pubmed ID: 21217072 Hypoxic Relaxation of Penile Arteries: Involvement of Endothelial Nitric Oxide and Modulation by Reactive Oxygen Species American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2010 | Pubmed ID: 20581086 Resveratrol Confers Endothelial Protection Via Activation of the Antioxidant Transcription Factor Nrf2 American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2010 | Pubmed ID: 20418481 Caveolin-1 Limits the Contribution of BK(Ca) Channel to EDHF-mediated Arteriolar Dilation: Implications in Diet-induced Obesity Cardiovascular Research. Sep, 2010 | Pubmed ID: 20299334 Reactive Oxygen Species and Cyclooxygenase 2-derived Thromboxane A2 Reduce Angiotensin II Type 2 Receptor Vasorelaxation in Diabetic Rat Resistance Arteries Hypertension. Feb, 2010 | Pubmed ID: 20026767 Cyclooxygenase-2 Derived Thromboxane A(2) and Reactive Oxygen Species Mediate Flow-induced Constrictions of Venules in Hyperhomocysteinemia Atherosclerosis. Jan, 2010 | Pubmed ID: 19615686 Resveratrol Attenuates Mitochondrial Oxidative Stress in Coronary Arterial Endothelial Cells American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2009 | Pubmed ID: 19749157 Mechanisms of Coronary Microvascular Adaptation to Obesity American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2009 | Pubmed ID: 19535672 Preserved Coronary Arteriolar Dilatation in Patients with Type 2 Diabetes Mellitus: Implications for Reactive Oxygen Species Pharmacological Reports : PR. Jan-Feb, 2009 | Pubmed ID: 19307697 Activation of Prostaglandin E2 EP1 Receptor Increases Arteriolar Tone and Blood Pressure in Mice with Type 2 Diabetes Cardiovascular Research. Jul, 2009 | Pubmed ID: 19299433 Where Have All the Stem Cells Gone? Circulation Research. Feb, 2009 | Pubmed ID: 19213961 High Intraluminal Pressure Via H2O2 Upregulates Arteriolar Constrictions to Angiotensin II by Increasing the Functional Availability of AT1 Receptors American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2008 | Pubmed ID: 18567710 High-fat Diet-induced Obesity Leads to Increased NO Sensitivity of Rat Coronary Arterioles: Role of Soluble Guanylate Cyclase Activation American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2008 | Pubmed ID: 18408126 Tissue-specific Regulation of Microvascular Diameter: Opposite Functional Roles of Neuronal and Smooth Muscle Located Vanilloid Receptor-1 Molecular Pharmacology. May, 2008 | Pubmed ID: 18256211 Contribution of Polyol Pathway to Arteriolar Dysfunction in Hyperglycemia. Role of Oxidative Stress, Reduced NO, and Enhanced PGH(2)/TXA(2) Mediation American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2007 | Pubmed ID: 17873009 Adaptation of Vasomotor Function of Human Coronary Arterioles to the Simultaneous Presence of Obesity and Hypertension Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2007 | Pubmed ID: 17823369 Asymmetrical Dimethylarginine Inhibits Shear Stress-induced Nitric Oxide Release and Dilation and Elicits Superoxide-mediated Increase in Arteriolar Tone Hypertension. Mar, 2007 | Pubmed ID: 17242303 H2O2 Increases Production of Constrictor Prostaglandins in Smooth Muscle Leading to Enhanced Arteriolar Tone in Type 2 Diabetic Mice American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2007 | Pubmed ID: 16997891 Up-regulation of Vascular Cyclooxygenase-2 in Diabetes Mellitus Pharmacological Reports : PR. 2006 | Pubmed ID: 17332672 Activation of the Poly(ADP-ribose) Polymerase Pathway in Human Heart Failure Molecular Medicine (Cambridge, Mass.). Jul-Aug, 2006 | Pubmed ID: 17088946 Increased Cyclooxygenase-2 Expression and Prostaglandin-mediated Dilation in Coronary Arterioles of Patients with Diabetes Mellitus Circulation Research. Sep, 2006 | Pubmed ID: 16917094 High-fat Diet-induced Reduction in Nitric Oxide-dependent Arteriolar Dilation in Rats: Role of Xanthine Oxidase-derived Superoxide Anion American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2006 | Pubmed ID: 16798827 The Levosimendan Metabolite OR-1896 Elicits Vasodilation by Activating the K(ATP) and BK(Ca) Channels in Rat Isolated Arterioles British Journal of Pharmacology. Jul, 2006 | Pubmed ID: 16715115 Phosphorylation-dependent Desensitization by Anandamide of Vanilloid Receptor-1 (TRPV1) Function in Rat Skeletal Muscle Arterioles and in Chinese Hamster Ovary Cells Expressing TRPV1 Molecular Pharmacology. Mar, 2006 | Pubmed ID: 16338989 Type 2 Diabetic Mice Have Increased Arteriolar Tone and Blood Pressure: Enhanced Release of COX-2-derived Constrictor Prostaglandins Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2005 | Pubmed ID: 15947245 PECAM-1 Mediates NO-dependent Dilation of Arterioles to High Temporal Gradients of Shear Stress Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2005 | Pubmed ID: 15890968 Expression and Distribution of Vanilloid Receptor 1 (TRPV1) in the Adult Rat Brain Brain Research. Molecular Brain Research. Apr, 2005 | Pubmed ID: 15857679 Nitric Oxide and H2O2 Contribute to Reactive Dilation of Isolated Coronary Arterioles American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2004 | Pubmed ID: 15319207 Biphasic Effect of Hydrogen Peroxide on Skeletal Muscle Arteriolar Tone Via Activation of Endothelial and Smooth Muscle Signaling Pathways Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2004 | Pubmed ID: 15208297 Ghrelin Induces Vasoconstriction in the Rat Coronary Vasculature Without Altering Cardiac Peptide Secretion American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2004 | Pubmed ID: 15142846 Microvascular Dysfunction After Transient High Glucose is Caused by Superoxide-dependent Reduction in the Bioavailability of NO and BH(4) American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2004 | Pubmed ID: 15044190 PPARgamma Activation, by Reducing Oxidative Stress, Increases NO Bioavailability in Coronary Arterioles of Mice with Type 2 Diabetes American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2004 | Pubmed ID: 14551045 Oxidative Stress-induced Dysregulation of Arteriolar Wall Shear Stress and Blood Pressure in Hyperhomocysteinemia is Prevented by Chronic Vitamin C Treatment American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2003 | Pubmed ID: 12869370 Superoxide-NO Interaction Decreases Flow- and Agonist-induced Dilations of Coronary Arterioles in Type 2 Diabetes Mellitus American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2003 | Pubmed ID: 12805026 Chronic Renal Failure Leads to Reduced Flow-dependent Dilation in Isolated Rat Skeletal Muscle Arterioles Due to Lack of NO Mediation Kidney & Blood Pressure Research. 2003 | Pubmed ID: 12697973 Lack of Nitric Oxide Mediation of Flow-dependent Arteriolar Dilation in Type I Diabetes is Restored by Sepiapterin Journal of Vascular Research. Jan-Feb, 2003 | Pubmed ID: 12644725 On the Role of Mechanosensitive Mechanisms Eliciting Reactive Hyperemia American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2002 | Pubmed ID: 12427591 Electrophysiological Effects of Risperidone in Mammalian Cardiac Cells Naunyn-Schmiedeberg's Archives of Pharmacology. Oct, 2002 | Pubmed ID: 12237749 Impaired Nitric Oxide-mediated Flow-induced Coronary Dilation in Hyperhomocysteinemia: Morphological and Functional Evidence for Increased Peroxynitrite Formation The American Journal of Pathology. Jul, 2002 | Pubmed ID: 12107099 New Trends in the Development of Oral Antidiabetic Drugs Current Medicinal Chemistry. Jan, 2002 | Pubmed ID: 11860348 Xanthine Oxidase-derived Reactive Oxygen Species Convert Flow-induced Arteriolar Dilation to Constriction in Hyperhomocysteinemia: Possible Role of Peroxynitrite Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2002 | Pubmed ID: 11788457 Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using Pressure Myography Ravirajsinh N. Jadeja1, Vikrant Rachakonda2, Zsolt Bagi3, Sandeep Khurana1 1Section of Gastroenterology and Hepatology, Georgia Regents University, 2Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, 3Vascular Biology Center, Georgia Regents University JoVE 50997 Medicine
Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using Pressure Myography Ravirajsinh N. Jadeja1, Vikrant Rachakonda2, Zsolt Bagi3, Sandeep Khurana1 1Section of Gastroenterology and Hepatology, Georgia Regents University, 2Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, 3Vascular Biology Center, Georgia Regents University JoVE 50997 Medicine