3D Visualization of Bone Remodeling Under Tensile Load in Suture Expansion Mice

August 18, 2023

PEGASOS Tissue Clearing Technique to Visualize Bone Remodeling (Video) | JoVE

01:26 min

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Sagittal Suture Expansion Surgery to Prepare Mouse Suture Expansion Model (Video) | JoVE

02:56 min

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PEGASOS Method to Prepare Transparent Tissues and Calvarial Bones

02:35 min

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Ziduan Ding², Ruomei Li², Yufeng Duan², Zhenxia Li², Bing Fang², Dian Jing²

¹Department of Orthodontics, China Shanghai Ninth People’s Hospital, College of Stomatology,Shanghai Jiao Tong University School of Medicine, ²National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology,Shanghai Jiao Tong University

Summary

This protocol presents a standardized suture expansion mouse model and a 3-D visualization method to study the mechanobiological changes of the suture and bone remodeling under tensile force loading.

3D Visualization of Bone Remodeling Under Tensile Load in Suture Expansion Mice

PEGASOS Tissue Clearing Technique to Visualize Bone Remodeling (Video) | JoVE

Sagittal Suture Expansion Surgery to Prepare Mouse Suture Expansion Model (Video) | JoVE

PEGASOS Method to Prepare Transparent Tissues and Calvarial Bones

Summary

Article