1Institute of Biological and Chemical Systems – Biological Information Processing,Karlsruhe Institute of Technology – Campus Nord, 2DITABIS AG – Digital Biomedical Imaging Systems AG, 3Centre for Organismal Studies,Heidelberg University, 4School of Biosciences,University of Birmingham, 5Institute for Automation and Applied Informatics,Karlsruhe Institute of Technology – Campus Nord, 6Department of Bioanalytical Ecotoxicology,Helmholtz-Centre for Environmental Research – UFZ
We describe a screening system’s workflow and data analysis for evaluating chemical compound toxicity based on the zebrafish embryo vibration startle response. The system records the movements of zebrafish embryos upon exposure to a vibration stimulus and allows for an integrated evaluation of general toxicity/lethality and neuromuscular toxicity.
