1Department of Microbiology and Immunology, College of Medicine,National Cheng Kung University, 2Department of Dermatology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 3Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 4National Institute of Infectious Diseases and Vaccinology,National Health Research Institutes, 5Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 6Insititute of Basic Medical Sciences, College of Medicine,National Cheng Kung University, 7Department of Biochemistry and Molecular Biology, College of Medicine,National Cheng Kung University, 8Center of Applied Nanomedicine,National Cheng Kung University
Betydningen av små kolonier i Candida spp. stoffresistens har ikke blitt fullstendig utforsket. Antimikrobiell fotodynamisk terapi (aPDT) tilbyr en lovende strategi mot stoffresistente soppinfeksjoner. Denne studien viser at rose bengal-mediert aPDT effektivt deaktiverer Candida glabrata og induserer petite kolonier, og presenterer en unik prosedyre.
