1Department of Microbiology and Immunology, College of Medicine,National Cheng Kung University, 2Department of Dermatology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 3Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 4National Institute of Infectious Diseases and Vaccinology,National Health Research Institutes, 5Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 6Insititute of Basic Medical Sciences, College of Medicine,National Cheng Kung University, 7Department of Biochemistry and Molecular Biology, College of Medicine,National Cheng Kung University, 8Center of Applied Nanomedicine,National Cheng Kung University
La importancia de las colonias pequeñas en la resistencia a los medicamentos de Candida spp. no se ha explorado completamente. La terapia fotodinámica antimicrobiana (aPDT) ofrece una estrategia prometedora contra las infecciones fúngicas resistentes a los medicamentos. Este estudio demuestra que la aPDT mediada por rosa de bengala desactiva eficazmente la Candida glabrata e induce colonias pequeñas, presentando un procedimiento único.
