Stabilizing a Femur Osteotomy with a Plate Fixation in <i>Ambystoma mexicanum</i>

Anastasia Polikarpova; Christian Bucher; Agnes Ellinghaus; Helena Okulski; Georg Duda; Katharina Schmidt-Bleek; Elly Margaret Tanaka

doi:10.3791/66648

Using Plate Fixation to Study Bone Healing and Limb Regeneration in Axolotls

April 12, 2024

Author Spotlight: Exploring Regeneration in Axolotls Through Insights in Cellular and Molecular Mechanisms, Bone Healing, and Implications for Human Therapies

01:57 min

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Anastasia Polikarpova, Christian Bucher, Agnes Ellinghaus³, Helena Okulski, Georg Duda, Katharina Schmidt-Bleek³, Elly Margaret Tanaka

¹Research Institute of Molecular Pathology, ²Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration,Berlin Institute of Health at Charité – Universitätsmedizin Berlin, ³Berlin Institute of Health Centre for Regenerative Therapies,Berlin Institute of Health at Charité – Universitätsmedizin Berlin

Summary

A protocol for femoral osteotomy surgery with the use of internal plate fixation in mature axolotls is presented. The procedure can be used to perform comparative studies on limb regeneration and fracture healing in aquatic amphibians.

Using Plate Fixation to Study Bone Healing and Limb Regeneration in Axolotls

Author Spotlight: Exploring Regeneration in Axolotls Through Insights in Cellular and Molecular Mechanisms, Bone Healing, and Implications for Human Therapies

Summary

Article