Katrin Zeilinger Brandenburg Center for Regenerative Therapies Charité University Medicine Berlin Biography Publications Institution JoVE Articles Katrin Zeilinger has not added a biography. If you are Katrin Zeilinger and would like to personalize this page please email our Author Liaison for assistance. Publications Periodic Harvesting of Embryonic Stem Cells from a Hollow-fiber Membrane Based Four-compartment Bioreactor Biotechnology Progress. Jan, 2016 | Pubmed ID: 26486457 Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI Mediators of Inflammation. 2015 | Pubmed ID: 26491234 Feasibility Study of an Active Wound Dressing Based on Hollow Fiber Membranes in a Porcine Wound Model Burns : Journal of the International Society for Burn Injuries. Jun, 2015 | Pubmed ID: 25451146 Featured Article: Isolation, Characterization, and Cultivation of Human Hepatocytes and Non-parenchymal Liver Cells Experimental Biology and Medicine (Maywood, N.J.). May, 2015 | Pubmed ID: 25394621 State-of-the-art of 3D Cultures (organs-on-a-chip) in Safety Testing and Pathophysiology ALTEX. 2014 | Pubmed ID: 25027500 Phenotypical Characterization of 6-21-week Gestational Age Human Dermis and Epidermal Cell Isolation Methods for in Vitro Studies on Epidermal Progenitors Burns : Journal of the International Society for Burn Injuries. Mar, 2013 | Pubmed ID: 22749444 Serum-free Culture of Primary Human Hepatocytes in a Miniaturized Hollow-fibre Membrane Bioreactor for Pharmacological in Vitro Studies Journal of Tissue Engineering and Regenerative Medicine. Nov, 2012 | Pubmed ID: 23165723 Analysis of Drug Metabolism Activities in a Miniaturized Liver Cell Bioreactor for Use in Pharmacological Studies Biotechnology and Bioengineering. Dec, 2012 | Pubmed ID: 22688505 Active Wound Dressing with Artificial Capillaries for Temporary Wound Irrigation and Skin Cell Supply Artificial Organs. Apr, 2012 | Pubmed ID: 22074237 Compartmental Hollow Fiber Capillary Membrane-based Bioreactor Technology for in Vitro Studies on Red Blood Cell Lineage Direction of Hematopoietic Stem Cells Tissue Engineering. Part C, Methods. Feb, 2012 | Pubmed ID: 21933020 Toward Preclinical Predictive Drug Testing for Metabolism and Hepatotoxicity by Using in Vitro Models Derived from Human Embryonic Stem Cells and Human Cell Lines - a Report on the Vitrocellomics EU-project Alternatives to Laboratory Animals : ATLA. May, 2011 | Pubmed ID: 21639679 Perfusion Circuit Concepts for Hollow-fiber Bioreactors Used As in Vitro Cell Production Systems or Ex Vivo Bioartificial Organs The International Journal of Artificial Organs. May, 2011 | Pubmed ID: 21623585 Cell Therapeutic Options in Liver Diseases: Cell Types, Medical Devices and Regulatory Issues Journal of Materials Science. Materials in Medicine. May, 2011 | Pubmed ID: 21461918 In-depth Physiological Characterization of Primary Human Hepatocytes in a 3D Hollow-fiber Bioreactor Journal of Tissue Engineering and Regenerative Medicine. Aug, 2011 | Pubmed ID: 21442764 Cytochrome P450-dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-dimensional Bioreactor Drug Metabolism and Disposition: the Biological Fate of Chemicals. Jul, 2011 | Pubmed ID: 21436404 Scaling Down of a Clinical Three-dimensional Perfusion Multicompartment Hollow Fiber Liver Bioreactor Developed for Extracorporeal Liver Support to an Analytical Scale Device Useful for Hepatic Pharmacological in Vitro Studies Tissue Engineering. Part C, Methods. May, 2011 | Pubmed ID: 21210724 HepaRG Human Hepatic Cell Line Utility As a Surrogate for Primary Human Hepatocytes in Drug Metabolism Assessment in Vitro Journal of Pharmacological and Toxicological Methods. Jan-Feb, 2011 | Pubmed ID: 20460162 Optimization of a Serum-free Culture Medium for Mouse Embryonic Stem Cells Using Design of Experiments (DoE) Methodology Cytotechnology. Dec, 2010 | Pubmed ID: 20859764 Feasibility of Using Sodium Chloride As a Tracer for the Characterization of the Distribution of Matter in Complex Multi-compartment 3D Bioreactors for Stem Cell Culture The International Journal of Artificial Organs. Jun, 2010 | Pubmed ID: 20669145 Lidocaine/monoethylglycinexylidide Test, Galactose Elimination Test, and Sorbitol Elimination Test for Metabolic Assessment of Liver Cell Bioreactors Artificial Organs. Jun, 2010 | Pubmed ID: 20456323 Interwoven Four-compartment Capillary Membrane Technology for Three-dimensional Perfusion with Decentralized Mass Exchange to Scale Up Embryonic Stem Cell Culture Cells, Tissues, Organs. 2010 | Pubmed ID: 20197653 Three-dimensional Perfusion Bioreactor Culture Supports Differentiation of Human Fetal Liver Cells Tissue Engineering. Part A. Jun, 2010 | Pubmed ID: 20088704 Molecular Characterization of Cultured Adult Human Liver Progenitor Cells Tissue Engineering. Part C, Methods. Oct, 2010 | Pubmed ID: 19874131 Dynamic 3D Culture Promotes Spontaneous Embryonic Stem Cell Differentiation in Vitro Tissue Engineering. Part C, Methods. Feb, 2010 | Pubmed ID: 19382830 The Characterization Tool: A Knowledge-based Stem Cell, Differentiated Cell, and Tissue Database with a Web-based Analysis Front-end Stem Cell Research. Sep-Nov, 2009 | Pubmed ID: 19520631 Effect of Human Patient Plasma Ex Vivo Treatment on Gene Expression and Progenitor Cell Activation of Primary Human Liver Cells in Multi-compartment 3D Perfusion Bioreactors for Extra-corporeal Liver Support Biotechnology and Bioengineering. Jul, 2009 | Pubmed ID: 19274748 Isolation and Characterization of Adult Human Liver Progenitors from Ischemic Liver Tissue Derived from Therapeutic Hepatectomies Tissue Engineering. Part A. Jul, 2009 | Pubmed ID: 19108677 Evaluation and Optimization of Hepatocyte Culture Media Factors by Design of Experiments (DoE) Methodology Cytotechnology. Jul, 2008 | Pubmed ID: 19003182 Bioartificial Liver Systems: Why, What, Whither? Regenerative Medicine. Jul, 2008 | Pubmed ID: 18588477 Evaluation of Primary Human Liver Cells in Bioreactor Cultures for Extracorporeal Liver Support on the Basis of Urea Production Artificial Organs. Sep, 2006 | Pubmed ID: 16934097 Time Course of Primary Liver Cell Reorganization in Three-dimensional High-density Bioreactors for Extracorporeal Liver Support: an Immunohistochemical and Ultrastructural Study Tissue Engineering. Jul-Aug, 2004 | Pubmed ID: 15363168 Use of Primary Human Liver Cells Originating from Discarded Grafts in a Bioreactor for Liver Support Therapy and the Prospects of Culturing Adult Liver Stem Cells in Bioreactors: a Morphologic Study Transplantation. Sep, 2003 | Pubmed ID: 14501853 Extracorporeal Liver Support Based on Primary Human Liver Cells and Albumin Dialysis--treatment of a Patient with Primary Graft Non-function Journal of Hepatology. Oct, 2003 | Pubmed ID: 12971979 Porcine Endogenous Retroviruses: No Infection in Patients Treated with a Bioreactor Based on Porcine Liver Cells Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology. Oct, 2003 | Pubmed ID: 12957184 Recovery of Preservation-injured Primary Human Hepatocytes and Nonparenchymal Cells to Tissuelike Structures in Large-scale Bioreactors for Liver Support: an Initial Transmission Electron Microscopy Study Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. Mar-Apr, 2003 | Pubmed ID: 12746191 Three-dimensional Co-culture of Primary Human Liver Cells in Bioreactors for in Vitro Drug Studies: Effects of the Initial Cell Quality on the Long-term Maintenance of Hepatocyte-specific Functions Alternatives to Laboratory Animals : ATLA. Sep-Oct, 2002 | Pubmed ID: 12405881 Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells Victoria Kegel*1, Daniela Deharde*1, Elisa Pfeiffer1, Katrin Zeilinger2, Daniel Seehofer1, Georg Damm1 1Department of General-, Visceral- and Transplantation Surgery, Charité University Medicine Berlin, 2Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin JoVE 53069 生物学
Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells Victoria Kegel*1, Daniela Deharde*1, Elisa Pfeiffer1, Katrin Zeilinger2, Daniel Seehofer1, Georg Damm1 1Department of General-, Visceral- and Transplantation Surgery, Charité University Medicine Berlin, 2Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin JoVE 53069 生物学