Tracing <em>de novo</em> Lipids using Stable Isotope Labeling LC-TIMS-TOF MS/MS

Katherine D. Castro; Lilian Valadares Tose; Matthew Willetts; Melvin A. Park; Marcela Nouzova; Fernando G. Noriega; Francisco Fernandez-Lima

doi:10.3791/65590

Screening Lipid Structures Using Stable Isotope Labeling

August 23, 2024

De-novo-Verfolgung von Lipiden mittels stabiler Isotopenmarkierung LC-TIMS-TOF MS/MS

00:47 min

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Calibration of the Mass Spectrometer for Screening Lipids with Stable Isotope Labeling by LC-TIMS-TOF MS/MS

02:50 min

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LC-TIMS-TOF MS/MS Data Analysis for Screening Lipids with Stable Isotope Labeling

03:39 min

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Katherine D. Castro, Lilian Valadares Tose, Matthew Willetts, Melvin A. Park, Marcela Nouzova, Fernando G. Noriega⁵, Francisco Fernandez-Lima⁶

¹Deparment of Chemistry and Biochemistry,Florida International University, ²Bruker Daltonics Inc., ³Institute of Parasitology,Biology Centre CAS, ⁴Department of Biological Sciences,Florida International University, ⁵Department of Parasitology,University of South Bohemia, ⁶Biomolecular Sciences Institute,Florida International University

Summary

Hier wird eine Methode zum Screening von Lipidstrukturen durch Markierung stabiler Isotope unter Verwendung ihrer Retentionszeit, Mobilität und Fragmentierung vorgestellt.

Screening Lipid Structures Using Stable Isotope Labeling

De-novo-Verfolgung von Lipiden mittels stabiler Isotopenmarkierung LC-TIMS-TOF MS/MS

Calibration of the Mass Spectrometer for Screening Lipids with Stable Isotope Labeling by LC-TIMS-TOF MS/MS

LC-TIMS-TOF MS/MS Data Analysis for Screening Lipids with Stable Isotope Labeling

Summary

Article