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Chapters
- 00:05Title
- 01:13Fibrin Gel Preparation
- 02:03Mouse Surgical Preparation
- 03:25Fibrin Gel Placement
- 05:04Harvesting the Lung
- 06:12Results: Flourescence Micrographs of the Inside of Representative Lung Fibrin Gel Implants
- 07:22Conclusion
Recapitulation of the organ-specific microenvironment, which stimulates local angiogenesis, is indispensable for successful regeneration of damaged tissues. This report demonstrates a novel method to implant fibrin gels on the lung surface of living mouse in order to explore how the lung-specific microenvironment modulates angiogenesis and alveolar regeneration in adult mouse.
