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Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
 

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine

Article DOI: 10.3791/52600-v • 10:05 min • July 7th, 2016
July 7th, 2016 •
1, 2, 3, 2, 2, 4, 5, 1
1Surgery, University of Minnesota, 2Biomedical Engineering, University of Minnesota, 3Medtronic, Inc., 4Bioengineering, Rice University, 5Pharmacy, University of Wisconsin

章节

总结概括
Automatic Translation

We have developed a swine model for the target delivery of pharmacological agents within the pericardial space/fluid. Using this approach, the relative benefits of administered agents on induced atrial fibrillation, relative refractory periods and/or ischemic protection can be investigated.

Tags

Pharmacological Agents Pericardial Target Delivery Model Swine Experiment Surgical Procedures Transplant Outcomes Pacing Leads Refractory Period Electrical Stimulation Study Atrial Fibrillation Pericardial Space AF Burden Cardioplegia Cardiac Arrhythmias Eschemic Damage Swine Advantages Sensing Catheters Pacing Leads Pericardial Cradle Pericardial Fluid Volumes
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