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JoVE Journal Cancer Research
Native chromatine Immunoprecipitation met behulp van lymfkliertest Brain Tumor Neurospheres
 
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Native chromatine Immunoprecipitation met behulp van lymfkliertest Brain Tumor Neurospheres

Article DOI: 10.3791/57016-v • 09:31 min • January 29th, 2018
January 29th, 2018 •
1, 1,2, 3,4, 1,2, 1,2
1Department of Cell and Developmental Biology, University of Michigan Medical School, 2Department of Neurosurgery, University of Michigan Medical School, 3Cancer Research Summer Internship Program (CARSIP), Cancer Biology Program, University of Michigan Medical School, 4Department of Biology, University of Puerto Rico-Río Piedras Campus

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Epigenetische mechanismen worden regelmatig gewijzigd in glioma. Chromatine immunoprecipitation kan worden gebruikt om de gevolgen van genetische wijzigingen in glioma die voortvloeien uit wijzigingen in histone modificaties tot regeling van de chromatine structuur en gene transcriptie. Dit protocol beschrijft een native chromatine immunoprecipitation op lymfkliertest hersenen tumor neurospheres.

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Kankeronderzoek kwestie 131 chromatine immunoprecipitation epigenetica glioma neurosphere generatie histone modificaties
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