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建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试
JoVE 杂志
癌症研究
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JoVE 杂志 癌症研究
Establishment of Zebrafish Patient-Derived Xenografts from Pancreatic Cancer for Chemosensitivity Testing
DOI:

06:59 min

May 12, 2023

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Chapters

  • 00:04Introduction
  • 00:56Sample Processing
  • 03:11Establishment of Zebrafish‐Based Patient‐Derived Xenografts (zPDX)
  • 04:56Treatment and Imaging
  • 05:40Results: Establishment of Zebrafish‐Based Patient‐Derived Xenografts (zPDXs) from Primary Human Pancreatic Adenocarcinoma
  • 06:14Conclusion

Summary

自动翻译

临床前模型旨在提高癌症生物学知识并预测治疗效果。本文描述了基于斑马鱼的患者来源的带有肿瘤组织碎片的异种移植物(zPDX)的产生。zPDXs用化疗治疗,根据移植组织的细胞凋亡评估其治疗效果。

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