Nicholas T. Ktistakis Signalling Programme The Babraham Institute Biography Publications Institution JoVE Articles Nicholas T. Ktistakis has not added a biography. If you are Nicholas T. Ktistakis and would like to personalize this page please email our Author Liaison for assistance. Publications Monitoring Selective Autophagy of Mitochondria Using Super-resolution Microscopy Methods in Cell Biology. 2021 | Pubmed ID: 34311864 TFG Binds LC3C to Regulate ULK1 Localization and Autophagosome Formation The EMBO Journal. May, 2021 | Pubmed ID: 33932238 Sorting Nexin 5 Mediates Virus-induced Autophagy and Immunity Nature. Jan, 2021 | Pubmed ID: 33328639 CDK1, the Other 'Master Regulator' of Autophagy Trends in Cell Biology. Feb, 2021 | Pubmed ID: 33272830 ATG13 Dynamics in Nonselective Autophagy and Mitophagy: Insights from Live Imaging Studies and Mathematical Modeling Autophagy. May, 2021 | Pubmed ID: 32320309 Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform Developmental Cell. Oct, 2020 | Pubmed ID: 33108756 An MTORC1-to-CDK1 Switch Maintains Autophagy Suppression During Mitosis Molecular Cell. 01, 2020 | Pubmed ID: 31733992 Autophagosome Biogenesis Machinery Journal of Molecular Biology. Apr, 2020 | Pubmed ID: 31705882 Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform Developmental Cell. Sep, 2019 | Pubmed ID: 31353311 Who Plays the Ferryman: ATG2 Channels Lipids into the Forming Autophagosome The Journal of Cell Biology. Jun, 2019 | Pubmed ID: 31076453 In Praise of M. Anselmier Who First Used the Term "autophagie" in 1859 Autophagy. 2017 | Pubmed ID: 28837378 Correlative Live Cell and Super Resolution Imaging of Autophagosome Formation Methods in Enzymology. 2017 | Pubmed ID: 28253951 Assembly of Early Machinery for Autophagy Induction: Novel Insights from High Resolution Microscopy Oncotarget. Dec, 2016 | Pubmed ID: 27829241 Characterization of Atg38 and NRBF2, a Fifth Subunit of the Autophagic Vps34/PIK3C3 Complex Autophagy. Nov, 2016 | Pubmed ID: 27630019 Autophagy Initiation by ULK Complex Assembly on ER Tubulovesicular Regions Marked by ATG9 Vesicles Nature Communications. 08, 2016 | Pubmed ID: 27510922 Digesting the Expanding Mechanisms of Autophagy Trends in Cell Biology. Aug, 2016 | Pubmed ID: 27050762 Structure and Flexibility of the Endosomal Vps34 Complex Reveals the Basis of Its Function on Membranes Science (New York, N.Y.). Oct, 2015 | Pubmed ID: 26450213 ERES: Sites for Autophagosome Biogenesis and Maturation? Journal of Cell Science. Jan, 2015 | Pubmed ID: 25568152 Live-cell Imaging for the Assessment of the Dynamics of Autophagosome Formation: Focus on Early Steps Methods (San Diego, Calif.). Mar, 2015 | Pubmed ID: 25498007 Dynamics of Autophagosome Formation: a Pulse and a Sequence of Waves Biochemical Society Transactions. Oct, 2014 | Pubmed ID: 25233420 Imaging Autophagy Current Protocols in Cytometry. Jul, 2014 | Pubmed ID: 24984962 The Immune System GTPase GIMAP6 Interacts with the Atg8 Homologue GABARAPL2 and is Recruited to Autophagosomes PloS One. 2013 | Pubmed ID: 24204963 Dynamic Association of the ULK1 Complex with Omegasomes During Autophagy Induction Journal of Cell Science. Nov, 2013 | Pubmed ID: 24013547 Characteristics and Requirements of Basal Autophagy in HEK 293 Cells Autophagy. Jun, 2013 | Pubmed ID: 23800949 PIPing on Lysosome Tubes The EMBO Journal. Feb, 2013 | Pubmed ID: 23314746 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 How Phosphoinositide 3-phosphate Controls Growth Downstream of Amino Acids and Autophagy Downstream of Amino Acid Withdrawal Biochemical Society Transactions. Feb, 2012 | Pubmed ID: 22260663 Antibacterial Autophagy Occurs at PI(3)P-enriched Domains of the Endoplasmic Reticulum and Requires Rab1 GTPase Autophagy. Jan, 2011 | Pubmed ID: 20980813 What is the Advantage of a Transient Precursor in Autophagosome Biogenesis? Autophagy. Jan, 2011 | Pubmed ID: 20935487 The Autoimmunity-related GIMAP5 GTPase is a Lysosome-associated Protein Self/nonself. 7, 2010 | Pubmed ID: 21487483 Lipid Signaling and Homeostasis: PA- is Better Than PA-H, but What About Those PIPs? Science Signaling. 2010 | Pubmed ID: 21139136 Autophagosome Formation in Mammalian Cells Seminars in Immunopathology. Dec, 2010 | Pubmed ID: 20740284 Autophagy Requires Endoplasmic Reticulum Targeting of the PI3-kinase Complex Via Atg14L The Journal of Cell Biology. Aug, 2010 | Pubmed ID: 20713597 Regulation of Autophagy by Phosphatidylinositol 3-phosphate FEBS Letters. Apr, 2010 | Pubmed ID: 20074568 Modulation of Local PtdIns3P Levels by the PI Phosphatase MTMR3 Regulates Constitutive Autophagy Traffic (Copenhagen, Denmark). Apr, 2010 | Pubmed ID: 20059746 Synthesis and Biological Evaluation of Phosphatidylinositol Phosphate Affinity Probes Organic & Biomolecular Chemistry. Jan, 2010 | Pubmed ID: 20024134 Galpha(q)-mediated Plasma Membrane Translocation of Sphingosine Kinase-1 and Cross-activation of S1P Receptors Biochimica Et Biophysica Acta. May, 2009 | Pubmed ID: 19830907 Emerging Findings from Studies of Phospholipase D in Model Organisms (and a Short Update on Phosphatidic Acid Effectors) Biochimica Et Biophysica Acta. Sep, 2009 | Pubmed ID: 19345277 Making Autophagosomes: Localized Synthesis of Phosphatidylinositol 3-phosphate Holds the Clue Autophagy. Nov, 2008 | Pubmed ID: 18927492 Autophagosome Formation from Membrane Compartments Enriched in Phosphatidylinositol 3-phosphate and Dynamically Connected to the Endoplasmic Reticulum The Journal of Cell Biology. Aug, 2008 | Pubmed ID: 18725538 PA Binding of Phosphatidylinositol 4-phosphate 5-kinase Advances in Enzyme Regulation. 2008 | Pubmed ID: 18167315 Phosphatidic Acid- and Phosphatidylserine-binding Proteins Biochimica Et Biophysica Acta. Aug, 2006 | Pubmed ID: 16624617 Dynamics and Function of Phospholipase D and Phosphatidic Acid During Phagocytosis Traffic (Copenhagen, Denmark). Mar, 2006 | Pubmed ID: 16497229 Sphingosine Kinase 1 is an Intracellular Effector of Phosphatidic Acid The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15310762 Isolation and Identification of Phosphatidic Acid Targets from Plants The Plant Journal : for Cell and Molecular Biology. Aug, 2004 | Pubmed ID: 15272872 Effect of Priming on Activation and Localization of Phospholipase D-1 in Human Neutrophils European Journal of Biochemistry / FEBS. Jul, 2004 | Pubmed ID: 15206940 Hierarchy of Membrane-targeting Signals of Phospholipase D1 Involving Lipid Modification of a Pleckstrin Homology Domain The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12021265 Evaluating Autophagy Levels in Two Different Pancreatic Cell Models Using LC3 Immunofluorescence Felipe J. Renna1, Malena Herrera Lopez1, Maria Manifava2, Nicholas T. Ktistakis2, Maria I. Vaccaro1 1Instituto de Bioquimica y Medicina Molecular Prof Alberto Boveris (IBIMOL), Universidad de Buenos Aires, CONICET, 2Signalling Programme, The Babraham Institute JoVE 65005 Biologie Live Cell Imaging of Early Autophagy Events: Omegasomes and Beyond Eleftherios Karanasios1, Eloise Stapleton2, Simon A. Walker1, Maria Manifava1, Nicholas T. Ktistakis1 1Signalling Programme, The Babraham Institute, 2MRC Group, Cardiff School of Biosciences, Cardiff University JoVE 50484 Biologie
Evaluating Autophagy Levels in Two Different Pancreatic Cell Models Using LC3 Immunofluorescence Felipe J. Renna1, Malena Herrera Lopez1, Maria Manifava2, Nicholas T. Ktistakis2, Maria I. Vaccaro1 1Instituto de Bioquimica y Medicina Molecular Prof Alberto Boveris (IBIMOL), Universidad de Buenos Aires, CONICET, 2Signalling Programme, The Babraham Institute JoVE 65005 Biologie
Live Cell Imaging of Early Autophagy Events: Omegasomes and Beyond Eleftherios Karanasios1, Eloise Stapleton2, Simon A. Walker1, Maria Manifava1, Nicholas T. Ktistakis1 1Signalling Programme, The Babraham Institute, 2MRC Group, Cardiff School of Biosciences, Cardiff University JoVE 50484 Biologie