Oliver J. Müller Department of Internal Medicine III, German Centre for Cardiovascular Research University Hospital Kiel, Partner Site Hamburg/Kiel/Lübeck Biography Publications Institution JoVE Articles Oliver J. Müller has not added a biography. If you are Oliver J. Müller and would like to personalize this page please email our Author Liaison for assistance. Publications Semirational Bioengineering of AAV Vectors with Increased Potency and Specificity for Systemic Gene Therapy of Muscle Disorders Science Advances. 09, 2022 | Pubmed ID: 36129972 Translational Medicine: Towards Gene Therapy of Marfan Syndrome Journal of Clinical Medicine. Jul, 2022 | Pubmed ID: 35887698 TAVR for All? The Surgical Perspective Journal of Cardiovascular Development and Disease. Jul, 2022 | Pubmed ID: 35877585 Adeno-Associated Virus-Mediated Gene Transfer of Inducible Nitric Oxide Synthase to an Animal Model of Pulmonary Hypertension Human Gene Therapy. Sep, 2022 | Pubmed ID: 35850528 Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary? Journal of Clinical Medicine. Jun, 2022 | Pubmed ID: 35743448 Reduction of A-to-I RNA Editing in the Failing Human Heart Regulates Formation of Circular RNAs Basic Research in Cardiology. 06, 2022 | Pubmed ID: 35737129 The Transcription Factor EB (TFEB) Sensitizes the Heart to Chronic Pressure Overload International Journal of Molecular Sciences. May, 2022 | Pubmed ID: 35682624 Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations Biomedicines. Mar, 2022 | Pubmed ID: 35453559 [64/m-Pain in the Calves After 150 m Walking Distance : Preparation for the Medical Specialist Examination: Part 142] Der Internist. 04, 2022 | Pubmed ID: 35301547 Tissue Engineered Transcatheter Pulmonary Valved Stent Implantation: Current State and Future Prospect International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35054905 Skeletal Muscle Derived Musclin Protects the Heart During Pathological Overload Nature Communications. 01, 2022 | Pubmed ID: 35013221 Biodegradable Poly-ε-Caprolactone Scaffolds with ECFCs and IMSCs for Tissue-Engineered Heart Valves International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35008953 AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR Circulation Research. 01, 2022 | Pubmed ID: 34814703 Cardiac Fibroblast Growth Factor 23 Excess Does Not Induce Left Ventricular Hypertrophy in Healthy Mice Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 34778257 Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor-Associated Myocarditis: A Narrative Review JAMA Cardiology. 11, 2021 | Pubmed ID: 34232253 AAV-mediated Expression of NFAT Decoy Oligonucleotides Protects from Cardiac Hypertrophy and Heart Failure Basic Research in Cardiology. 06, 2021 | Pubmed ID: 34089101 Alginate Hydrogel Polymers Enable Efficient Delivery of a Vascular-targeted AAV Vector into Aortic Tissue Molecular Therapy. Methods & Clinical Development. Jun, 2021 | Pubmed ID: 33768132 Development of an AAV9-RNAi-mediated Silencing Strategy to Abrogate TRPM4 Expression in the Adult Heart Pflugers Archiv : European Journal of Physiology. Mar, 2021 | Pubmed ID: 33580817 AAV-mediated AP-1 Decoy Oligonucleotide Expression Inhibits Aortic Elastolysis in a Mouse Model of Marfan Syndrome Cardiovascular Research. 11, 2021 | Pubmed ID: 33471064 Circulating Uromodulin Inhibits Vascular Calcification by Interfering with Pro-inflammatory Cytokine Signalling Cardiovascular Research. 02, 2021 | Pubmed ID: 32243494 Identification of a Myotropic AAV by Massively Parallel in Vivo Evaluation of Barcoded Capsid Variants Nature Communications. 10, 2020 | Pubmed ID: 33116134 Common Mechanistic Pathways in Cancer and Heart Failure. A Scientific Roadmap on Behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) European Journal of Heart Failure. 12, 2020 | Pubmed ID: 33094495 [Treatment Recommendations in Cardio-oncology: Where Are We?] Der Internist. Nov, 2020 | Pubmed ID: 33025122 Dual Functional States of R406W-Desmin Assembly Complexes Cause Cardiomyopathy With Severe Intercalated Disc Derangement in Humans and in Knock-In Mice Circulation. 12, 2020 | Pubmed ID: 33023321 Prevention and Treatment of Venous Thromboembolism in Cancer Patients Herz. Nov, 2020 | Pubmed ID: 32564097 Cardiac Transcriptional and Metabolic Changes Following Thoracotomy Scientific Reports. 06, 2020 | Pubmed ID: 32541655 Interference with ERK-dimerization at the Nucleocytosolic Interface Targets Pathological ERK1/2 Signaling Without Cardiotoxic Side-effects Nature Communications. 04, 2020 | Pubmed ID: 32265441 AAV-mediated Cardiac Gene Transfer of Wild-type Desmin in Mouse Models for Recessive Desminopathies Gene Therapy. 11, 2019 | Pubmed ID: 32322014 AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts Molecular Therapy. Methods & Clinical Development. Dec, 2019 | Pubmed ID: 31720303 Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K Channel-Related Acid-Sensitive K Channel-1) (K3.1) K Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling Circulation. Arrhythmia and Electrophysiology. 09, 2019 | Pubmed ID: 31514528 ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the MTORC1 Activator, Rheb Circulation Research. 01, 2019 | Pubmed ID: 30582446 Comprehensive Plasma and Tissue Profiling Reveals Systemic Metabolic Alterations in Cardiac Hypertrophy and Failure Cardiovascular Research. 07, 2019 | Pubmed ID: 30418544 Cardio-oncology: Conflicting Priorities of Anticancer Treatment and Cardiovascular Outcome Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Apr, 2018 | Pubmed ID: 29453595 Evaluation of MYBPC3 Trans-Splicing and Gene Replacement As Therapeutic Options in Human IPSC-Derived Cardiomyocytes Molecular Therapy. Nucleic Acids. Jun, 2017 | Pubmed ID: 28624223 Mybpc3 Gene Therapy for Neonatal Cardiomyopathy Enables Long-term Disease Prevention in Mice Nature Communications. Dec, 2014 | Pubmed ID: 25463264 Paradoxical Effects on Force Generation After Efficient β1-adrenoceptor Knockdown in Reconstituted Heart Tissue The Journal of Pharmacology and Experimental Therapeutics. Apr, 2014 | Pubmed ID: 24431469 O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy Nesrin Schmiedel1, Anca Remes1, Mohsen Valadan2, Susanne Hille1, Andrea Matzen1, Derk Frank1, Norbert Frey2, Lorenz Lehmann2, Oliver J. Müller1 1Department of Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Kiel, Partner Site Hamburg/Kiel/Lübeck, 2Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Heidelberg, Partner Site Heidelberg/Mannheim JoVE 64455 Medizin
O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy Nesrin Schmiedel1, Anca Remes1, Mohsen Valadan2, Susanne Hille1, Andrea Matzen1, Derk Frank1, Norbert Frey2, Lorenz Lehmann2, Oliver J. Müller1 1Department of Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Kiel, Partner Site Hamburg/Kiel/Lübeck, 2Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Heidelberg, Partner Site Heidelberg/Mannheim JoVE 64455 Medizin