Samuel D. Rabkin Molecular Neurosurgery Laboratory and the Brain Tumor Research Center, Department of Neurosurgery Massachusetts General Hospital and Harvard Medical School Biography Publications Institution JoVE Articles Samuel D. Rabkin has not added a biography. If you are Samuel D. Rabkin and would like to personalize this page please email our Author Liaison for assistance. Publications Characterization and Oncolytic Virus Targeting of FAP-expressing Tumor-associated Pericytes in Glioblastoma Acta Neuropathologica Communications. 12, 2020 | Pubmed ID: 33308315 Myc Targeted CDK18 Promotes ATR and Homologous Recombination to Mediate PARP Inhibitor Resistance in Glioblastoma Nature Communications. 07, 2019 | Pubmed ID: 31266951 Oncolytic Virus Immunotherapy Induces Immunogenic Cell Death and Overcomes STING Deficiency in Melanoma Oncoimmunology. 2019 | Pubmed ID: 31143509 Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells Molecular Therapy Oncolytics. Jun, 2019 | Pubmed ID: 31016228 Restriction of Replication of Oncolytic Herpes Simplex Virus with a Deletion of γ34.5 in Glioblastoma Stem-Like Cells Journal of Virology. 08, 2018 | Pubmed ID: 29793956 Curing Glioblastoma: Oncolytic HSV-IL12 and Checkpoint Blockade Oncoscience. Jul, 2017 | Pubmed ID: 28966936 Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade Cancer Cell. 08, 2017 | Pubmed ID: 28810147 Oncolytic Herpes Simplex Virus Interactions with the Host Immune System Current Opinion in Virology. 12, 2016 | Pubmed ID: 27497296 EXPLORING THE ANTITUMOR EFFECT OF VIRUS IN MALIGNANT GLIOMA Drugs of the Future. 2015 | Pubmed ID: 26855472 Designing Herpes Viruses As Oncolytics Molecular Therapy Oncolytics. 2015 | Pubmed ID: 26462293 Treatment of Human Hepatocellular Carcinoma by the Oncolytic Herpes Simplex Virus G47delta Cancer Cell International. 2014 | Pubmed ID: 25360068 Reconstructing and Reprogramming the Tumor-propagating Potential of Glioblastoma Stem-like Cells Cell. Apr, 2014 | Pubmed ID: 24726434 Treatment of Orthotopic Malignant Peripheral Nerve Sheath Tumors with Oncolytic Herpes Simplex Virus Neuro-oncology. Aug, 2014 | Pubmed ID: 24470552 Multifaceted Oncolytic Virus Therapy for Glioblastoma in an Immunocompetent Cancer Stem Cell Model Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23754388 An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma Cell Reports. May, 2013 | Pubmed ID: 23707066 Current Status of Gene Therapy for Brain Tumors Translational Research : the Journal of Laboratory and Clinical Medicine. Apr, 2013 | Pubmed ID: 23246627 Oncolytic Herpes Simplex Virus Counteracts the Hypoxia-induced Modulation of Glioblastoma Stem-like Cells Stem Cells Translational Medicine. Apr, 2012 | Pubmed ID: 23197811 Effect of γ34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors Journal of Virology. Apr, 2012 | Pubmed ID: 22345479 Oncolytic Virus-mediated Manipulation of DNA Damage Responses: Synergy with Chemotherapy in Killing Glioblastoma Stem Cells Journal of the National Cancer Institute. Jan, 2012 | Pubmed ID: 22173583 Enhanced Antitumor Efficacy of Low-dose Etoposide with Oncolytic Herpes Simplex Virus in Human Glioblastoma Stem Cell Xenografts Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2011 | Pubmed ID: 21976549 A Novel Oncolytic Herpes Simplex Virus That Synergizes with Phosphoinositide 3-kinase/Akt Pathway Inhibitors to Target Glioblastoma Stem Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2011 | Pubmed ID: 21505062 Identification of the ENT1 Antagonists Dipyridamole and Dilazep As Amplifiers of Oncolytic Herpes Simplex Virus-1 Replication Cancer Research. May, 2010 | Pubmed ID: 20424118 Trichostatin A and Oncolytic HSV Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2008 | Pubmed ID: 18388912 Herpes Simplex Virus Us3(-) Mutant As Oncolytic Strategy and Synergizes with Phosphatidylinositol 3-kinase-Akt Targeting Molecular Therapeutics Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2007 | Pubmed ID: 17908985 Dominant-negative Fibroblast Growth Factor Receptor Expression Enhances Antitumoral Potency of Oncolytic Herpes Simplex Virus in Neural Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2006 | Pubmed ID: 17121900 Oncolytic HSV Armed with Platelet Factor 4, an Antiangiogenic Agent, Shows Enhanced Efficacy Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2006 | Pubmed ID: 17045531 Oncolytic Herpes Simplex Virus Vector Therapy of Breast Cancer in C3(1)/SV40 T-antigen Transgenic Mice Cancer Research. Feb, 2005 | Pubmed ID: 15735042 Oncolytic Herpes Simplex Virus Vectors for Cancer Virotherapy Cancer Gene Therapy. Dec, 2002 | Pubmed ID: 12522436 Growth, Purification, and Titration of Oncolytic Herpes Simplex Virus Hong-My Nguyen*1, Naresh Sah*1, Melissa R. M. Humphrey2, Samuel D. Rabkin2, Dipongkor Saha1 1Department of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 2Molecular Neurosurgery Laboratory and the Brain Tumor Research Center, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School JoVE 62677 Immunologie und Infektion
Growth, Purification, and Titration of Oncolytic Herpes Simplex Virus Hong-My Nguyen*1, Naresh Sah*1, Melissa R. M. Humphrey2, Samuel D. Rabkin2, Dipongkor Saha1 1Department of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 2Molecular Neurosurgery Laboratory and the Brain Tumor Research Center, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School JoVE 62677 Immunologie und Infektion