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Un<em> In Vitro</em> Dormienza Modello di estrogeno-sensibili cancro al seno nel midollo osseo: Uno strumento per gli studi molecolari del meccanismo e ipotesi Generation
JoVE Journal
Medizin
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JoVE Journal Medizin
An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation
DOI:

08:48 min

June 30, 2015

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Kapitel

  • 00:05Titel
  • 01:36Clonogenic Assay Plate Preparation
  • 04:13Clonogenic Assay
  • 06:34Results: Pi3 Kinase Inhibitors Activate the Doormant Phenotype in Estrogen Sensitive Cells
  • 07:59Conclusion

Summary

Automatische Übersetzung

We developed an in vitro model of dormancy in the bone marrow for estrogen-sensitive breast cancer cells. The goal of this protocol is to demonstrate use of the model for the study of the molecular and cellular biology of dormancy and for generation of hypotheses for subsequent testing in vivo.

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