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JoVE Journal Medicine
Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
 

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells

Article DOI: 10.3791/57637-v • 09:51 min • May 18th, 2018
May 18th, 2018 •
1, 2,3, 2,3
1Department of Biochemistry, School of Medicine, Case Western Reserve University, 2Department of Pediatrics, Division of Pediatric Hematology/Oncology, Case Western Reserve University, 3Angie Fowler Cancer Institute, Rainbow Babies & Children's Hospital, University Hospitals, Cleveland

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Summary
Automatic Translation

Here, we present a protocol to develop and characterize tolerogenic dendritic cells (TolDCs) and evaluate their immunotherapeutic utility.

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Murine Tolerogenic Dendritic Cells Functional Characterization Autoimmune Disorders Multiple Sclerosis Immunotherapeutic Utility Standardized Method Tolerogenic Dendritic Cell Therapy Tolerogenic Dendritic Cell Development Functional Efficacy Testing Cellular Immunotherapy Immune Response Hind Leg Bones C57BL/6 Mice Surgical Blades Forceps Tibias Femurs 70% Ethanol Marrow Collection
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