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Journal
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Krebsforschung
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Optimizing HCC Organoid Formation for Target Identification and Drug Development
/
Development and Optimization of A Human Hepatocellular Carcinoma Patient-Derived Organoid Model for Potential Target Identification and Drug Discovery
JoVE Journal
Krebsforschung
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JoVE Journal
Krebsforschung
Development and Optimization of A Human Hepatocellular Carcinoma Patient-Derived Organoid Model for Potential Target Identification and Drug Discovery
Development and Optimization of A Human Hepatocellular Carcinoma Patient-Derived Organoid Model for Potential Target Identification and Drug Discovery
Optimizing HCC Organoid Formation for Target Identification and Drug Development
DOI:
10.3791/65785-v
•
01:28 min
•
August 18, 2023
•
Cheng-Yang Zhang*
1,2
,
Xiao-Feng Zhang*
3
,
Jun Yuan*
1,2
,
Yuan-Feng Gong
,
Hui Tang
,
Wan-Yu Guo
2
,
Tong-Yan Li
2
,
Cai-Wen Li
2
,
Yun-Qiang Tang
,
Ning-Fang Ma
2
,
Ming Liu
2
1
Affiliated Cancer Hospital and Institute of Guangzhou Medical University
,
2
Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, Center for Cancer Research and Translational Medicine, School of Basic Medical Sciences
,
Guangzhou Medical University
,
3
Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center
,
Guangzhou Medical University
,
4
Department of Hepatobiliary Surgery, Affiliated Cancer Hospital
,
Guangzhou Medical University
Tags
Hepatocellular Carcinoma
Patient-derived Organoids
Cancer Pathogenesis
Drug Discovery
Therapeutic Targets
Organoid Culture
Cryopreservation
Genetic Similarity
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