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Development of a Click-Based Assay for Screening HAT1 Enzyme Activity
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An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
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Biochemie
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JoVE Journal Biochemie
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation

An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation

Development of a Click-Based Assay for Screening HAT1 Enzyme Activity

DOI:
10.3791/66054-v

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01:28 min

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January 26, 2024

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, , ,
1Departments of Internal Medicine and the Green Center for Reproductive Biology Sciences,University of Texas Southwestern Medical Center, 2Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences,Wayne State University

Tags

Acetyl-Click Chemistry AssayHistone Acetyltransferase 1 (HAT1)Acetyl Transferase ActivityHigh Throughput ScreeningSmall Molecule InhibitorsPeptide SubstrateEnzymatic AssayChromatin SynthesisTumor GrowthCancer Treatment

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An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
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Click Assay for the Measurement of Histone Acetyltransferase 1 Acetylation

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