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Journal
/
Biochemie
/
Development of a Click-Based Assay for Screening HAT1 Enzyme Activity
/
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
JoVE Journal
Biochemie
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JoVE Journal
Biochemie
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
Development of a Click-Based Assay for Screening HAT1 Enzyme Activity
DOI:
10.3791/66054-v
•
01:28 min
•
January 26, 2024
•
Shreenidhi Rajkumar
,
Danielle Dixon
,
Andrew M. Lipchik
,
Joshua J. Gruber
1
Departments of Internal Medicine and the Green Center for Reproductive Biology Sciences
,
University of Texas Southwestern Medical Center
,
2
Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences
,
Wayne State University
Tags
Acetyl-Click Chemistry Assay
Histone Acetyltransferase 1 (HAT1)
Acetyl Transferase Activity
High Throughput Screening
Small Molecule Inhibitors
Peptide Substrate
Enzymatic Assay
Chromatin Synthesis
Tumor Growth
Cancer Treatment
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check_url/de/66054?article_type=v
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
check_url/de/66054?article_type=v
Click Assay for the Measurement of Histone Acetyltransferase 1 Acetylation
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