情感自传回忆的神经关联的脑成像研究
Summary
我们提出了一个协议，允许调查回味的情感自传体记忆体，使用功能磁共振成像的神经关联。该协议可用于健康和临床参与者。
Abstract
情感自传式记忆体（AMS）的回忆，重要的是健康的认知和情感的运作1 -记住积极AMS是增加个人的福祉和自尊2，而可能会导致记忆和负面的 AM反刍3情感性精神障碍。虽然已取得重大进展，在了解底层AM一般的检索（4，5审查），少的是情感的主观上的AMS和相关的神经关联重新体验的影响已知的脑机制。这部分是由于这样的事实，不像实验室为基础的微观活动（6，7-9审查）内存情感效应的调查，很多时候，我的研究没有明确的重点在情感方面记住个人事件（见10）。在这里，我们提出了一个协议，允许调查回味的情感队使用功能性磁共振成像（fMRI）的神经关联。这些记忆的线索收集，扫描前问卷（AMQ）的自传体记忆的手段，因此，基于现象学的属性（即强度，生动性，个人的意义）选择适当的情感肺泡。该协议可用于健康和临床人群的一致好评。
Protocol
1。收集和选择回忆，成像任务，和实验协议收集情绪肺泡个人的回忆引起每个参与者在之前进行的fMRI会议接受记者采访时，类似的非情感的AMS（ 例如，11，12）所采用的程序。不像大多数以前的技术，我们的AMQ是专门建造目标评估个人情感的情节和他们recollective的属性。行为研究中常用的方法，利用脑成像研究适应涉及Crovitz和技术希夫曼13日至15日 ，?…
Discussion
这里介绍实验设计允许的记忆情感的自传体记忆的神经相关性的调查。这种设计有可能推进我们的大脑如何产生情感偏见（正或负），在记忆的个人记忆的知识，以及如何将这些偏差可能是由检索的重点调制（情绪或情感方面）。该协议有额外的好处，它也可用于临床的人群（如抑郁症和创伤后应激障碍患者），这使得调查上午检索的负面情感偏见的改变（例如，负面的经验反刍创伤性事件和不?…
Divulgaciones
The authors have nothing to disclose.
Acknowledgements
支持这项研究是由来自美国国家精神分裂症和抑郁症研究联盟和从加拿大精神病学研究基金会（FD）的俄共奖的青年研究者奖。海关支持由惠氏CIHR博士后奖学金。作者衷心感谢彼得赛里斯援助，协助数据分析fMRI数据收集和克里斯蒂娜孙明扬。
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Tags
Brain ImagingNeural CorrelatesEmotional Autobiographical RecollectionAM RetrievalPersonal Well-beingSelf-esteemAffective DisordersEmotion Effect On MemoryLaboratory-based MicroeventsNeural Correlates Of Emotional AMsFunctional Magnetic Resonance Imaging (fMRI)Autobiographical Memory Questionnaire (AMQ)Healthy PopulationsClinical Populations
Citar este artículo
Denkova, E., Chakrabarty, T., Dolcos, S., Dolcos, F. Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection. J. Vis. Exp. (54), e2396, doi:10.3791/2396 (2011).