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Orthotopic Small Bowel Transplantation in Rats
 

Orthotopic Small Bowel Transplantation in Rats

Article DOI: 10.3791/4102-v • 09:16 min • November 6th, 2012
November 6th, 2012 •
*1,2, *1, 1, 1, 1, 1, 1, 2, 1, 1
1Department of Surgery, University of Bonn, Germany, 2Department of Surgery, Kyoto University Hospital
* These authors contributed equally

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Small bowel transplantation has become an accepted treatment option for patients with irreversible intestinal failure. Our experimental model of orthotopic small bowel transplantation in rats serves as a reliable tool to address underlying immunologic and inflammatory processes that complicate intestinal transplantation.

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Orthotopic Small Bowel Transplantation Rats Short Gut Syndrome Parenteral Nutrition Irreversible Intestinal Failure Graft Survival Quality Of Life Solid Organ Transplantation Graft Function Immunologic Alterations Acute Rejection Sepsis Chronic Graft Failure Long Term Outcome Passenger Leucocytes Gut Associated Lymphoid System (GALT) Immunogenity Intestinal Graft Commensals Pathogens Sepsis Episodes Mucosal Integrity Animal Models
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