Waiting
Procesando inicio de sesión ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Behavior / Creating Dynamic Images of Short-lived Dopamine…
JoVE Journal
Behavior

Esto contenido es Open Access.

JoVE Journal Behavior
Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET
 

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking

Article DOI: 10.3791/50358-v • 14:21 min • August 6th, 2013
August 6th, 2013 •
1,2,3,4, 1,3, 1,3,4, 3,4, 5, 6, 1,2,3
1Diagnostic Radiology, Yale University, 2Psychiatry, Yale University, 3Yale PET Center, Yale University, 4Biomedical Engineering, Yale University, 5Nuclear Medicine, Massachusetts General Hospital, 6Radiological Sciences, University of California, Irvine

Capítulos

Resumen
Automatic Translation

We present a novel PET imaging approach for capturing dopamine fluctuations induced by cigarette smoking. Subjects smoke in the PET scanner. Dynamic PET images are modeled voxel-by-voxel in time by lp-ntPET, which includes a time-varying dopamine term. The results are 'movies' of dopamine fluctuations in the striatum during smoking.

Tags

Dynamic Images Lp-ntPET Dopamine Fluctuations Cigarette Smoking Dopamine Movies Brain Imaging PET Data Analysis Kinetic Models Time-varying Parameters Neurotransmitter Release Statistical Comparison Masking Visualization Preprocessing
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter