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Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina
 

Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina

Article DOI: 10.3791/50932-v • 08:28 min • February 22nd, 2014
February 22nd, 2014 •
*1, *1, 1, 1
1CRTD / DFG-Research Center for Regenerative Therapies Dresden, Technische Universität Dresden
* These authors contributed equally

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Resumen
Automatic Translation

Cell transplantation represents a strategy for the treatment of retinal degeneration characterized by photoreceptor loss. Here we describe a method for enrichment of transplantable photoreceptors and their subretinal grafting into adult mice.

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Subretinal Transplantation MACS Purification Photoreceptor Precursor Cells Adult Mouse Retina Vision Impairment Blindness Cell Transplantation Clinical Applications Degenerated Photoreceptors Preclinical Studies Neonatal Mouse Retina Subretinal Transplantation Mature Photoreceptor Morphology Synaptic Terminals Endogenous Bipolar Cells Donor Photoreceptors Integration Neural Circuitry Cell Replacement Approach Purified Cell Suspensions Correct Cell Placement Enrichment Of Photoreceptor Precursors Magnetic-associated Cell Sorting (MACS) Transplantable Rod Photoreceptor Precursors
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