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Implantation of Inferior Vena Cava Interposition Graft in Mouse Model
 

Implantation of Inferior Vena Cava Interposition Graft in Mouse Model

Article DOI: 10.3791/51632-v • 12:39 min • June 4th, 2014
June 4th, 2014 •
1, 1, 1, 1, 1, 2, 1,3
1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Department of Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital

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Resumen
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To improve our knowledge of cellular and molecular neotissue formation, a murine model of the TEVG was recently developed. The grafts were implanted as infrarenal vena cava interposition grafts in C57BL/6 mice. This model achieves similar results to those achieved in our clinical investigation, but over a far shortened time-course.

Tags

Inferior Vena Cava Interposition Graft Biodegradable Scaffolds Bone Marrow Mononuclear Cells (BMCs) Reconstructive Surgery Congenital Cardiac Anomalies Stenosis Vascular Neotissue Formation Tissue Engineered Vascular Grafts (TEVGs) Polyglycolic Acid Nonwoven Felt Mesh & 949;-caprolactone And L-lactide Copolymer Lyophilizer Vacuumed Desiccator Density Gradient Centrifugation Infrarenal Vena Cava Interposition Grafts C57BL/6 Mice Patency Thromboembolic Complications Aneurysmal Formation Murine Model
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