Elisa Laurenti Wellcome and Medical Research Council Cambridge Stem Cell Institute, Department of Haematology University of Cambridge Biography Publications Institution JoVE Articles Elisa Laurenti has not added a biography. If you are Elisa Laurenti and would like to personalize this page please email our Author Liaison for assistance. Publications Convergent Somatic Evolution Commences in Utero in a Germline Ribosomopathy Nature Communications. Aug, 2023 | Pubmed ID: 37608017 Circulating IRF8-expressing CD123CD127 Lymphoid Progenitors: Key Players in Human Hematopoiesis Trends in Immunology. Sep, 2023 | Pubmed ID: 37591714 Yolk Sac Cell Atlas Reveals Multiorgan Functions During Human Early Development Science (New York, N.Y.). Aug, 2023 | Pubmed ID: 37590359 Primitive Haematopoiesis in the Human Placenta Gives Rise to Macrophages with Epigenetically Silenced HLA-DR Nature Communications. Mar, 2023 | Pubmed ID: 36997537 Diverse Mutational Landscapes in Human Lymphocytes Nature. Aug, 2022 | Pubmed ID: 35948631 STAT1 is Essential for HSC Function and Maintains MHCIIhi Stem Cells That Resist Myeloablation and Neoplastic Expansion Blood. Oct, 2022 | Pubmed ID: 35767701 Hyaluronic Acid-GPRC5C Signalling Promotes Dormancy in Haematopoietic Stem Cells Nature Cell Biology. Jul, 2022 | Pubmed ID: 35725769 Clonal Dynamics of Haematopoiesis Across the Human Lifespan Nature. Jun, 2022 | Pubmed ID: 35650442 Unique Molecular and Functional Features of Extramedullary Hematopoietic Stem and Progenitor Cell Reservoirs in Humans Blood. Jun, 2022 | Pubmed ID: 35073399 Simultaneous Analysis of Single-Cell Transcriptomes and Cell Surface Protein Expression of Human Hematopoietic Stem Cells and Progenitors Using the 10x Genomics Platform Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 34766273 Immature Acute Leukaemias: Lessons from the Haematopoietic Roadmap The FEBS Journal. Aug, 2022 | Pubmed ID: 34028982 Hematopoietic Stem and Progenitor Cells Outside the Bone Marrow: Where, When, and Why Experimental Hematology. Dec, 2021 | Pubmed ID: 34687807 Blood and Immune Development in Human Fetal Bone Marrow and Down Syndrome Nature. Oct, 2021 | Pubmed ID: 34588693 Hematopoietic Stem Cells Retain Functional Potential and Molecular Identity in Hibernation Cultures Stem Cell Reports. Jun, 2021 | Pubmed ID: 33961793 Somatic Mutation Landscapes at Single-molecule Resolution Nature. May, 2021 | Pubmed ID: 33911282 Single-cell Multi-omics Analysis of the Immune Response in COVID-19 Nature Medicine. May, 2021 | Pubmed ID: 33879890 Transcriptional Characterization of Human Megakaryocyte Polyploidization and Lineage Commitment Journal of Thrombosis and Haemostasis : JTH. May, 2021 | Pubmed ID: 33587817 Sphingosine-1-phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote Differentiation Blood Cancer Discovery. Jan, 2021 | Pubmed ID: 33458693 A Transcriptomic Continuum of Differentiation Arrest Identifies Myeloid Interface Acute Leukemias with Poor Prognosis Leukemia. Mar, 2021 | Pubmed ID: 32655144 Blood Stem Cells SELect Quiescence Blood. Dec, 2020 | Pubmed ID: 33367552 Chronic Lymphocytic Leukemia Increases the Pool of Peripheral Blood Hematopoietic Stem Cells and Skews Differentiation Blood Advances. Dec, 2020 | Pubmed ID: 33351125 Beyond "to Divide or Not to Divide": Kinetics Matters in Hematopoietic Stem Cells Experimental Hematology. Dec, 2020 | Pubmed ID: 33188890 Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal Cell Stem Cell. Nov, 2019 | Pubmed ID: 31631013 Decoding Human Fetal Liver Haematopoiesis Nature. Oct, 2019 | Pubmed ID: 31597962 A Track of the Clones: New Developments in Cellular Barcoding Experimental Hematology. Dec, 2018 | Pubmed ID: 30448259 Myelo-lymphoid Lineage Restriction Occurs in the Human Haematopoietic Stem Cell Compartment Before Lymphoid-primed Multipotent Progenitors Nature Communications. Oct, 2018 | Pubmed ID: 30291229 Population Dynamics of Normal Human Blood Inferred from Somatic Mutations Nature. Sep, 2018 | Pubmed ID: 30185910 From Haematopoietic Stem Cells to Complex Differentiation Landscapes Nature. Jan, 2018 | Pubmed ID: 29364285 Early Loss of Crebbp Confers Malignant Stem Cell Properties on Lymphoid Progenitors Nature Cell Biology. Sep, 2017 | Pubmed ID: 28825697 Human Megakaryocytes: Finding the Root Blood. Jun, 2017 | Pubmed ID: 28642357 DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation Cell Stem Cell. Dec, 2016 | Pubmed ID: 27867036 A Single-cell Resolution Map of Mouse Hematopoietic Stem and Progenitor Cell Differentiation Blood. Aug, 2016 | Pubmed ID: 27365425 Molecular Landscapes of Human Hematopoietic Stem Cells in Health and Leukemia Annals of the New York Academy of Sciences. Apr, 2016 | Pubmed ID: 26663266 Distinct Routes of Lineage Development Reshape the Human Blood Hierarchy Across Ontogeny Science (New York, N.Y.). Jan, 2016 | Pubmed ID: 26541609 CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells Cell Stem Cell. Mar, 2015 | Pubmed ID: 25704240 The Unfolded Protein Response Governs Integrity of the Haematopoietic Stem-cell Pool During Stress Nature. Jun, 2014 | Pubmed ID: 24776803 Estimating Dormant and Active Hematopoietic Stem Cell Kinetics Through Extensive Modeling of Bromodeoxyuridine Label-retaining Cell Dynamics PloS One. Sep, 2009 | Pubmed ID: 19771180 Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis Emily F. Calderbank1, Laura Magnani1, Elisa Laurenti1 1Wellcome and Medical Research Council Cambridge Stem Cell Institute, Department of Haematology, University of Cambridge JoVE 66315 Biologie
Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis Emily F. Calderbank1, Laura Magnani1, Elisa Laurenti1 1Wellcome and Medical Research Council Cambridge Stem Cell Institute, Department of Haematology, University of Cambridge JoVE 66315 Biologie