Vicki Stone Institute of Biochemical Chemistry, Biophysics, and Bioengineering Heriot-Watt University Biography Publications Institution JoVE Articles Vicki Stone has not added a biography. If you are Vicki Stone and would like to personalize this page please email our Author Liaison for assistance. Publications Critical Aspects in Dissolution Testing of Nanomaterials in the Oro-gastrointestinal Tract: the Relevance of Juice Composition for Hazard Identification and Grouping Nanoscale Advances. Jan, 2024 | Pubmed ID: 38298600 How to Formulate Hypotheses and IATAs to Support Grouping and Read-across of Nanoforms ALTEX. 2023 | Pubmed ID: 35796348 Grouping of Orally Ingested Silica Nanomaterials Via Use of an Integrated Approach to Testing and Assessment to Streamline Risk Assessment Particle and Fibre Toxicology. Dec, 2022 | Pubmed ID: 36461106 Editorial to the Special Issue on "similarity Assessment of Nanoforms: Concepts, Tools and Case Studies of the GRACIOUS Project" NanoImpact. Oct, 2022 | Pubmed ID: 36427811 Comparison of In Vitro Approaches to Assess the Antibacterial Effects of Nanomaterials Journal of Functional Biomaterials. Nov, 2022 | Pubmed ID: 36412895 Assessing the Transferability and Reproducibility of 3D in Vitro Liver Models from Primary Human Multi-cellular Microtissues to Cell-line Based HepG2 Spheroids Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2022 | Pubmed ID: 36108805 Grouping MWCNTs Based on Their Similar Potential to Cause Pulmonary Hazard After Inhalation: a Case-study Particle and Fibre Toxicology. Jul, 2022 | Pubmed ID: 35854357 Transgenic Zebrafish Larvae As a Non-rodent Alternative Model to Assess Pro-inflammatory (neutrophil) Responses to Nanomaterials Nanotoxicology. Apr, 2022 | Pubmed ID: 35797989 Integrated Approaches to Testing and Assessment for Grouping Nanomaterials Following Dermal Exposure Nanotoxicology. Apr, 2022 | Pubmed ID: 35704509 Determining Nanoform Similarity Via Assessment of Surface Reactivity by Abiotic and in Vitro Assays NanoImpact. Apr, 2022 | Pubmed ID: 35560290 Bayesian Based Similarity Assessment of Nanomaterials to Inform Grouping NanoImpact. Jan, 2022 | Pubmed ID: 35559895 How Can We Justify Grouping of Nanoforms for Hazard Assessment? Concepts and Tools to Quantify Similarity NanoImpact. Jan, 2022 | Pubmed ID: 35559874 The Application of Existing Genotoxicity Methodologies for Grouping of Nanomaterials: Towards an Integrated Approach to Testing and Assessment Particle and Fibre Toxicology. May, 2022 | Pubmed ID: 35525968 An Investigation of the Hepatic Toxicity of PEGylated Polymeric Redox Responsive Nanoparticles RSC Advances. Apr, 2022 | Pubmed ID: 35496338 The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability-A PATROLS Perspective on New Approach Methodologies Small (Weinheim an Der Bergstrasse, Germany). Apr, 2022 | Pubmed ID: 35324067 Development of a Standard Operating Procedure for the DCFH-DA Acellular Assessment of Reactive Oxygen Species Produced by Nanomaterials Toxicology Mechanisms and Methods. Jul, 2022 | Pubmed ID: 35086424 An in Vitro Assessment of the Toxicity of Two-dimensional Synthetic and Natural Layered Silicates Toxicology in Vitro : an International Journal Published in Association with BIBRA. Feb, 2022 | Pubmed ID: 34801683 Particulate and Drug-induced Toxicity Assessed in Novel Quadruple Cell Human Primary Hepatic Disease Models of Steatosis and Pre-fibrotic NASH Archives of Toxicology. Jan, 2022 | Pubmed ID: 34668024 An Integrated Approach to Testing and Assessment of High Aspect Ratio Nanomaterials and Its Application for Grouping Based on a Common Mesothelioma Hazard NanoImpact. Apr, 2021 | Pubmed ID: 35559971 Pulmonary Toxicity and Gene Expression Changes After Short-term Inhalation Exposure to Surface-modified Copper Oxide Nanoparticles NanoImpact. Apr, 2021 | Pubmed ID: 35559970 Acute Waterborne and Chronic Sediment Toxicity of Silver and Titanium Dioxide Nanomaterials Towards the Oligochaete, Lumbriculus Variegatus NanoImpact. Jan, 2021 | Pubmed ID: 35559780 Acute Hazard Assessment of Silver Nanoparticles Following Intratracheal Instillation, Oral and Intravenous Injection Exposures Nanotoxicology. Dec, 2021 | Pubmed ID: 35015612 An Integrated Approach to Testing and Assessment to Support Grouping and Read-Across of Nanomaterials After Inhalation Exposure Applied in Vitro Toxicology. Sep, 2021 | Pubmed ID: 34746334 Grouping Hypotheses and an Integrated Approach to Testing and Assessment of Nanomaterials Following Oral Ingestion Nanomaterials (Basel, Switzerland). Oct, 2021 | Pubmed ID: 34685072 Time Dependent Impact of Copper Oxide Nanomaterials on the Expression of Genes Associated with Oxidative Stress, Metal Binding, Inflammation and Mucus Secretion in Single and Co-culture Intestinal in Vitro Models Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2021 | Pubmed ID: 33839236 Neutrophil Activation by Nanomaterials : Comparing Strengths and Limitations of Primary Human Cells with Those of an Immortalized (HL-60) Cell Line Nanotoxicology. Feb, 2021 | Pubmed ID: 33272088 Risk Management Framework for Nano-Biomaterials Used in Medical Devices and Advanced Therapy Medicinal Products Materials (Basel, Switzerland). Oct, 2020 | Pubmed ID: 33066064 An In Vitro Lung System to Assess the Proinflammatory Hazard of Carbon Nanotube Aerosols International Journal of Molecular Sciences. Jul, 2020 | Pubmed ID: 32727099 Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study Nanomaterials (Basel, Switzerland). Jul, 2020 | Pubmed ID: 32707981 A Method to Assess the Relevance of Nanomaterial Dissolution During Reactivity Testing Materials (Basel, Switzerland). May, 2020 | Pubmed ID: 32414026 A Review of Hepatic Nanotoxicology - Summation of Recent Findings and Considerations for the Next Generation of Study Designs Journal of Toxicology and Environmental Health. Part B, Critical Reviews. May, 2020 | Pubmed ID: 32321383 Polylactic is a Sustainable, Low Absorption, Low Autofluorescence Alternative to Other Plastics for Microfluidic and Organ-on-Chip Applications Analytical Chemistry. May, 2020 | Pubmed ID: 32233401 Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes ACS Nano. Apr, 2020 | Pubmed ID: 32167743 Ongoing Inflammation Enhances the Toxicity of Engineered Nanomaterials: Application of an in Vitro Co-culture Model of the Healthy and Inflamed Intestine Toxicology in Vitro : an International Journal Published in Association with BIBRA. Mar, 2020 | Pubmed ID: 31760064 Assessment of Nanomaterial-induced Hepatotoxicity Using a 3D Human Primary Multi-cellular Microtissue Exposed Repeatedly over 21 days - the Suitability of the in Vitro System As an in Vivo Surrogate Particle and Fibre Toxicology. Nov, 2019 | Pubmed ID: 31739797 The Variances in Cytokine Production Profiles from Non- or Activated THP-1, Kupffer Cell and Human Blood Derived Primary Macrophages Following Exposure to Either Alcohol or a Panel of Engineered Nanomaterials PloS One. 2019 | Pubmed ID: 31393970 The Mechanism-based Toxicity Screening of Particles with Use in the Food and Nutrition Sector Via the ToxTracker Reporter System Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2019 | Pubmed ID: 31279906 Using 3D Gastrointestinal Tract in Vitro Models with Microfold Cells and Mucus Secreting Ability to Assess the Hazard of Copper Oxide Nanomaterials Journal of Nanobiotechnology. May, 2019 | Pubmed ID: 31113462 The Importance of Inter-individual Kupffer Cell Variability in the Governance of Hepatic Toxicity in a 3D Primary Human Liver Microtissue Model Scientific Reports. May, 2019 | Pubmed ID: 31086251 The Influence of Organic Modification on the Cytotoxicity of Clay Particles to Keratinocytes, Hepatocytes and Macrophages; an Investigation Towards the Safe Use of Polymer-clay Nanocomposite Packaging Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Apr, 2019 | Pubmed ID: 30797875 Toxicity of Copper Oxide and Basic Copper Carbonate Nanoparticles After Short-term Oral Exposure in Rats Nanotoxicology. Feb, 2019 | Pubmed ID: 30451559 Comparative, Collaborative, and Integrative Risk Governance for Emerging Technologies Environment Systems & Decisions. May, 2018 | Pubmed ID: 37829286 Nanodelivery Systems and Stabilized Solid-drug Nanoparticles for Orally Administered Medicine: Current Landscape International Journal of Nanomedicine. 2018 | Pubmed ID: 30510419 Assessing the Bioactivity of Crystalline Silica in Heated High-temperature Insulation Wools Inhalation Toxicology. 2018 | Pubmed ID: 30328741 Quantitative Human Health Risk Assessment Along the Lifecycle of Nano-scale Copper-based Wood Preservatives Nanotoxicology. Sep, 2018 | Pubmed ID: 29893192 Transformations of Nanoenabled Copper Formulations Govern Release, Antifungal Effectiveness, and Sustainability Throughout the Wood Protection Lifecycle Environmental Science & Technology. Feb, 2018 | Pubmed ID: 29373787 The Essential Elements of a Risk Governance Framework for Current and Future Nanotechnologies Risk Analysis : an Official Publication of the Society for Risk Analysis. Jul, 2018 | Pubmed ID: 29240986 Adoption of in Vitro Systems and Zebrafish Embryos As Alternative Models for Reducing Rodent Use in Assessments of Immunological and Oxidative Stress Responses to Nanomaterials Critical Reviews in Toxicology. Mar, 2018 | Pubmed ID: 29239234 Transcriptional Profiling Reveals Gene Expression Changes Associated with Inflammation and Cell Proliferation Following Short-term Inhalation Exposure to Copper Oxide Nanoparticles Journal of Applied Toxicology : JAT. Mar, 2018 | Pubmed ID: 29094763 Aligning Nanotoxicology with the 3Rs: What is Needed to Realise the Short, Medium and Long-term Opportunities? Regulatory Toxicology and Pharmacology : RTP. Dec, 2017 | Pubmed ID: 29069581 Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge Environmental Health Perspectives. 10, 2017 | Pubmed ID: 29017987 Impact of Copper Oxide Nanomaterials on Differentiated and Undifferentiated Caco-2 Intestinal Epithelial Cells; Assessment of Cytotoxicity, Barrier Integrity, Cytokine Production and Nanomaterial Penetration Particle and Fibre Toxicology. Aug, 2017 | Pubmed ID: 28835236 Development of an in Vitro Co-culture Model to Mimic the Human Intestine in Healthy and Diseased State Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2017 | Pubmed ID: 28807632 The Effect of Aluminium and Sodium Impurities on the in Vitro Toxicity and Pro-inflammatory Potential of Cristobalite Environmental Research. Nov, 2017 | Pubmed ID: 28802207 Silver Nanoparticles and Metallic Silver Interfere with the Griess Reaction: Reduction of Azo Dye Formation Via a Competing Sandmeyer-Like Reaction Chemical Research in Toxicology. Apr, 2017 | Pubmed ID: 28282135 Complete Transformation of ZnO and CuO Nanoparticles in Culture Medium and Lymphocyte Cells During Toxicity Testing Nanotoxicology. Mar, 2017 | Pubmed ID: 28165880 Impact of Serum As a Dispersion Agent for in Vitro and in Vivo Toxicological Assessments of TiO Nanoparticles Archives of Toxicology. Jan, 2017 | Pubmed ID: 26872950 A Tractable Method for Measuring Nanomaterial Risk Using Bayesian Networks Nanoscale Research Letters. Dec, 2016 | Pubmed ID: 27848238 Advancing Risk Analysis for Nanoscale Materials: Report from an International Workshop on the Role of Alternative Testing Strategies for Advancement Risk Analysis : an Official Publication of the Society for Risk Analysis. Aug, 2016 | Pubmed ID: 27510619 Synthesis, Characterization and Evaluation of in Vitro Toxicity in Hepatocytes of Linear Polyesters with Varied Aromatic and Aliphatic Co-monomers Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2016 | Pubmed ID: 27498019 Neurodegenerative and Neurological Disorders by Small Inhaled Particles Neurotoxicology. Sep, 2016 | Pubmed ID: 27448464 Approaches to Develop Alternative Testing Strategies to Inform Human Health Risk Assessment of Nanomaterials Risk Analysis : an Official Publication of the Society for Risk Analysis. Aug, 2016 | Pubmed ID: 27285586 Organ Burden and Pulmonary Toxicity of Nano-sized Copper (II) Oxide Particles After Short-term Inhalation Exposure Nanotoxicology. Oct, 2016 | Pubmed ID: 27132941 Expert Consensus on an in Vitro Approach to Assess Pulmonary Fibrogenic Potential of Aerosolized Nanomaterials Archives of Toxicology. Jul, 2016 | Pubmed ID: 27121469 A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 2016 | Pubmed ID: 27030582 A Rapid Screening Assay for Identifying Mycobacteria Targeted Nanoparticle Antibiotics Nanotoxicology. Aug, 2016 | Pubmed ID: 26618564 Exploring the Cellular and Tissue Uptake of Nanomaterials in a Range of Biological Samples Using Multimodal Nonlinear Optical Microscopy Nanotechnology. Dec, 2015 | Pubmed ID: 26584818 Assessing the Acute Hazards of Zinc Oxide Nanomaterials to Lumbriculus Variegatus Ecotoxicology (London, England). Aug, 2015 | Pubmed ID: 26173674 Multi-walled Carbon Nanotube Induced Frustrated Phagocytosis, Cytotoxicity and Pro-inflammatory Conditions in Macrophages Are Length Dependent and Greater Than That of Asbestos Toxicology in Vitro : an International Journal Published in Association with BIBRA. Oct, 2015 | Pubmed ID: 26086123 Comparative Hazard Identification by a Single Dose Lung Exposure of Zinc Oxide and Silver Nanomaterials in Mice PloS One. 2015 | Pubmed ID: 25966284 Mechanism of Neutrophil Activation and Toxicity Elicited by Engineered Nanomaterials Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2015 | Pubmed ID: 25962642 Nanomaterial Categorization for Assessing Risk Potential to Facilitate Regulatory Decision-making ACS Nano. 2015 | Pubmed ID: 25791861 Accumulation Dynamics and Acute Toxicity of Silver Nanoparticles to Daphnia Magna and Lumbriculus Variegatus: Implications for Metal Modeling Approaches Environmental Science & Technology. Apr, 2015 | Pubmed ID: 25756614 Hepatic Toxicology Following Single and Multiple Exposure of Engineered Nanomaterials Utilising a Novel Primary Human 3D Liver Microtissue Model Particle and Fibre Toxicology. Oct, 2014 | Pubmed ID: 25326698 Serum Enhanced Cytokine Responses of Macrophages to Silica and Iron Oxide Particles and Nanomaterials: a Comparison of Serum to Lung Lining Fluid and Albumin Dispersions Journal of Applied Toxicology : JAT. Nov, 2014 | Pubmed ID: 24737200 ITS-NANO - Prioritising Nanosafety Research to Develop a Stakeholder Driven Intelligent Testing Strategy Particle and Fibre Toxicology. 2014 | Pubmed ID: 24521051 The Role of Kupffer Cells in the Hepatic Response to Silver Nanoparticles Nanotoxicology. Aug, 2014 | Pubmed ID: 24344730 An in Vitro Assessment of Panel of Engineered Nanomaterials Using a Human Renal Cell Line: Cytotoxicity, Pro-inflammatory Response, Oxidative Stress and Genotoxicity BMC Nephrology. Apr, 2013 | Pubmed ID: 23617532 Engineered Nanomaterial Risk. Lessons Learnt from Completed Nanotoxicology Studies: Potential Solutions to Current and Future Challenges Critical Reviews in Toxicology. Jan, 2013 | Pubmed ID: 23126553 Effects of Silver Nanoparticles on the Liver and Hepatocytes in Vitro Toxicological Sciences : an Official Journal of the Society of Toxicology. Feb, 2013 | Pubmed ID: 23086748 Primary Human Hepatocytes Versus Hepatic Cell Line: Assessing Their Suitability for in Vitro Nanotoxicology Nanotoxicology. Nov, 2013 | Pubmed ID: 23009365 In Vitro Assessment of Engineered Nanomaterials Using a Hepatocyte Cell Line: Cytotoxicity, Pro-inflammatory Cytokines and Functional Markers Nanotoxicology. May, 2013 | Pubmed ID: 22263564 Investigating the Relationship Between Nanomaterial Hazard and Physicochemical Properties: Informing the Exploitation of Nanomaterials Within Therapeutic and Diagnostic Applications Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2012 | Pubmed ID: 22940205 Quantum Dots: an Insight and Perspective of Their Biological Interaction and How This Relates to Their Relevance for Clinical Use Theranostics. 2012 | Pubmed ID: 22896769 An in Vitro Liver Model--assessing Oxidative Stress and Genotoxicity Following Exposure of Hepatocytes to a Panel of Engineered Nanomaterials Particle and Fibre Toxicology. Jul, 2012 | Pubmed ID: 22812506 Author Spotlight: Innovating Thiol Quantification and Biomarker Detection for Oxidative Stress Research Craig McBeth1, David Brown2, Pawel Pokorski2, Lydia Lei2, Vicki Stone2 1School of Health and Life Sciences, Teesside University, 2Institute of Biochemical Chemistry, Biophysics, and Bioengineering, Heriot-Watt University JoVE 66267 Biochimie
Author Spotlight: Innovating Thiol Quantification and Biomarker Detection for Oxidative Stress Research Craig McBeth1, David Brown2, Pawel Pokorski2, Lydia Lei2, Vicki Stone2 1School of Health and Life Sciences, Teesside University, 2Institute of Biochemical Chemistry, Biophysics, and Bioengineering, Heriot-Watt University JoVE 66267 Biochimie