1Department of Microbiology and Immunology, College of Medicine,National Cheng Kung University, 2Department of Dermatology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 3Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 4National Institute of Infectious Diseases and Vaccinology,National Health Research Institutes, 5Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 6Insititute of Basic Medical Sciences, College of Medicine,National Cheng Kung University, 7Department of Biochemistry and Molecular Biology, College of Medicine,National Cheng Kung University, 8Center of Applied Nanomedicine,National Cheng Kung University
Il significato delle piccole colonie nella resistenza ai farmaci di Candida spp. non è stato completamente esplorato. La terapia fotodinamica antimicrobica (aPDT) offre una strategia promettente contro le infezioni fungine resistenti ai farmaci. Questo studio dimostra che l’aPDT mediata dal bengala rosa disattiva efficacemente la Candida glabrata e induce piccole colonie, presentando una procedura unica.
