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Analyzing Petite Colony Formation and Drug Resistance in Candida glabrata

March 29th, 2024
*1,2, *3, 4,5, 1,2, 6, 2, 3, 1,6, 2,7,8
1Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, 2Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 3Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 4National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, 5Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 6Insititute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 7Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 8Center of Applied Nanomedicine, National Cheng Kung University
* These authors contributed equally

Summary
Automatic Translation

Betydningen af petite kolonier i Candida spp. lægemiddelresistens er ikke blevet undersøgt fuldt ud. Antimikrobiel fotodynamisk terapi (aPDT) tilbyder en lovende strategi mod lægemiddelresistente svampeinfektioner. Denne undersøgelse viser, at rose bengal-medieret aPDT effektivt deaktiverer Candida glabrata og inducerer petite kolonier, hvilket præsenterer en unik procedure.

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