Rollins School of Public Health 1 article published in JoVE Medicine A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers Anna Ree1, Benjamin Rapsas2, Chanse Denmon1, Mark Vernon1, Sheila AM Rauch1,2, Ying Guo3, Xiangqin Cui1,3, Jennifer S Stevens1,2, Venkatagiri Krishnamurthy1,2, Vitaly Napadow4, Jessica A Turner5, Anna Woodbury1,2 1Atlanta Veterans Affairs Healthcare System, 2Emory University School of Medicine, 3Rollins School of Public Health, 4Spaulding Rehabilitation Hospital, Harvard Medical School, 5The Ohio State University Wexner Medical Center The current study is a randomized, placebo-controlled trial to determine the efficacy of cranial electrical stimulation (CES) for improving pain and function in fibromyalgia and further develop resting functional connectivity magnetic resonance imaging (rs-fcMRI) as a clinical tool to assess the neural correlates and mechanisms of chronic pain and analgesic response.