Hays Innovations 1 article published in JoVE Medicine Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine Aaron M. Williams*1, Umar F. Bhatti*1, Isabel S. Dennahy1, Kiril Chtraklin1, Panpan Chang1, Nathan J. Graham1, Basil M. Baccouche1, Shalini Roy1, Mohammed Harajli1, Jing Zhou1, Vahagn C. Nikolian1, Qiufang Deng1, Yuzi Tian1, Baoling Liu1, Yongqing Li1, Gregory L. Hays1,2, Julia L. Hays1,2, Hasan B. Alam1 1Department of Surgery, University of Michigan, 2Hays Innovations Here, we present a protocol demonstrating a hemorrhagic shock model in swine that uses aortic occlusion as a bridge to definitive care in trauma. This model has application in testing a wide range of surgical and pharmacological therapeutic strategies.